• This model possesses a 17 base pair deletion in exon 8 of MET
• This model is provided as a heterozygous knockout; homozygous knockout of MET is not viable
• Background Strain: Sprague-Dawley

Availability: Cryopreserved as heterozygous embryos
Zygosity: Heterozygous

Generated in partnership with Autism Speaks, this model possesses a deletion in exon 8 of MET receptor tyrosine kinase (MET). Mutations in MET have been associated with the autism spectrum disorders in human patients, and this model is useful for the study of autism.

Homozygous knockout of MET is embryonic lethal.