Chrna7 knockout rats: HsdSage:SD-Chrna7tm1Sage GEM rats - raybetAPP,雷电竞下载苹果app,雷竞技reybat下载

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Chrna7 knockout rats

HsdSage:SD-Chrna7^tm1Sage

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Cryopreserved as heterozygous embryos

Availability: Cryopreserved as heterozygous embryos
Zygosity: Heterozygous

This model is a biallelic deletion of the Chrna7 gene, part a family of ligand-gated ion channels that mediate fast signal transmission at synapses. Disruptions of this gene have been shown to be involved in juvenile myoclonic epilepsy and schizophrenia.

Origin:

The Chrna7 Knockout Rat model was originally created at SAGE Labs, Inc. in St. Louis, MO and distributed out of the Boyertown, PA facility. The line continues to be maintained through the original SAGE Labs animal inventory acquired by Envigo.

Available regions:

Asia-Pacific Austria Baltic states Belgium East Europe France Germany Ireland Italy Portugal Scandinavia Spain Switzerland The Netherlands United States United Kingdom Other regions

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Model information sheet

Research use and related publications

Epilepsy
Neuronal growth and transport studies
Schizophrenia

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