Discover critical factors to consider when selecting your animal model and why
Download e-bookThe R2G2 brings a new option to oncology and immunology researchers
Download white paperTackle your biggest rederivation hurdles with help from our experienced project managers
年代tream the webinarLearn how antibodies may be used to support the development of therapeutic products
Download white paperWhat comes out of your research depends in large part on what goes into your research models. Ensuring your study animals have the most appropriate diet is critical to maintaining consistent, reliable research data.
Reaching your goals in diabetes and obesity studies can be a challenge or a success depending on the reliability of your research models. TheLeprdbmutation was discovered in 1966 in the inbred BKS mouse strain. This model has since been well characterized as a model of Type 2 diabetes mellitus, exhibiting commonly published metabolic symptoms including hyperglycemia and hyperinsulinemia.
From Dunn Nutritional Laboratory, Cambridge, United Kingdom; to Olac, United Kingdom, in 1979; to Harlan, United States in 2000. Harlan became Envigo in 2015.
Our breeding scheme maintainsDock7mandLeprdbin repulsion. These genes are closely linked; however, recombination could occur. Our mice are most likely nonrecombinants, but they have not been tested.
描述 | Price | Currency |
---|---|---|
3-4 weeks | 133.95 | USD |
4-5 weeks | 133.95 | USD |
5-6 weeks | 136.90 | USD |
6-7 weeks | 140.45 | USD |
7-8 weeks | 143.60 | USD |
Over 8 weeks, add per week | 5.15 | USD |
Retired breeder | 114.25 | USD |
Envigo uses well-established techniques to successfully produce time mated rats, mice, hamsters, and rabbits. We use an Impedence Meter for determining the stage of estrus in rats prior to breeding. Time mated rats and mice are determined by observation of a vaginal plug. Plug date is considered to be day zero (0) of gestation.
Due to the natural variation in the length of gestation, the exact day of parturition cannot be guaranteed. In addition, Envigo cannot guarantee the minimum number of offspring per litter.
Please be aware that late-term pregnant animals may deliver their litter prematurely while in transit, and depending on the circumstances involved, requests for credit or replacement of these animals may be declined at our sole discretion.
如果问题关于孕龄或怀孕are encountered, customers should immediately contact Envigo’s Customer Service Department and provide detailed information regarding the animals involved.
Expected Pregnancy Rate | |||
---|---|---|---|
年代tock or Strain | Timed mated <13 days gestation (at shipping) | Timed mated ≥ 13 days gestation and over (at shipping) | Untimed pregnant ≥ 13 days gestation (at shipping) |
Outbred | * | 90% | 90% ** |
Inbred | * | 90% | 90% ** |
* Plug guarantee only; no guaranteed pregnancy. Plug date = Day 0.
** Untimed pregnant rodents will be selected from our breeding colonies on the basis of palpation or visual confirmation. A variation of three to four days gestation can be expected. Therefore Envigo cannot be held responsible for actual gestation and/or exact day of littering.
To avoid charges, cancellations for timed mated animals must be receivedone week prior to mating date.
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