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    Diabetes

    Al-Romaiyan, A., King, A. J., Persaud, S. J., & Jones, P. M. (2013).,一种新型的体育术提取物改善体内葡萄糖耐量,并刺激体外胰岛素分泌和合成。, Phytotherapy Research : PTR, 27(7), 1006-1011. doi:10.1002/ptr.4815 [doi]
    Irwin, N., Frizelle, P., Montgomery, I. A., Moffett, R. C., O'Harte, F. P., & Flatt, P. R. (2012).,Beneficial effects of the novel cholecystokinin agonist (pGlu-gln)-CCK-8 in mouse models of obesity/diabetes., Diabetologia, 55(10), 2747-2758. doi:10.1007/s00125-012-2654-6 [doi]
    Zuellig,R. A.,Hornemann,T.,Othman,A.,Hehl,A. B.,Bode,H.,Guntert,T.,。。。Sonda,S。(2014)。,Deoxysphingolipids, novel biomarkers for type 2 diabetes, are cytotoxic for insulin-producing cells.,糖尿病,63(4),1326-1339。DOI:10.2337 / dB13-1042 [DOI]
    Hauge-Evans, A. C., Reers, C., Kerby, A., Franklin, Z., Amisten, S., King, A. J., . . . Jones, P. M. (2014).,Effect of hyperglycaemia on muscarinic M3 receptor expression and secretory sensitivity to cholinergic receptor activation in islets.,糖尿病,肥胖和新陈代谢,16(10),947-956。DOI:10.1111 / DOM.12301 [DOI]
    Irles, E., Neco, P., Lluesma, M., Villar-Pazos, S., Santos-Silva, J. C., Vettorazzi, J. F., . . . Quesada, I. (2015).,增强的葡萄糖诱导的细胞内信号传导促进胰岛素高度分泌:胰腺β细胞功能适应遗传肥胖和前脂脂的模型。, Molecular and Cellular Endocrinology, 404, 46-55. doi:10.1016/j.mce.2015.01.033 [doi]
    Giannulis, I., Mondini, E., Cinti, F., Frontini, A., Murano, I., Barazzoni, R., . . . Cinti, S. (2014).,Increased density of inhibitory noradrenergic parenchymal nerve fibers in hypertrophic islets of langerhans of obese mice.,营养,新陈代谢和心血管疾病:NMCD,24(4),384-392。DOI:10.1016 / J.Numecd.2013.09.006 [DOI]
    Tubbs,E.,Theurey,P.,小瓶,G.,Bendridi,N.,Bravard,A.,Chauvin,M。A.,。。。rieusset,J.(2014)。,Mitochondria-associated endoplasmic reticulum membrane (MAM) integrity is required for insulin signaling and is implicated in hepatic insulin resistance., Diabetes, 63(10), 3279-3294. doi:10.2337/db13-1751 [doi]
    Amit Mechlovich, D, T, Bar-Am, O,发现,O。& Youdim, M. B. (2014).,Molecular targets of the multifunctional iron-chelating drug, M30, in the brains of mouse models of type 2 diabetes mellitus., British Journal of Pharmacology, 171(24), 5636-5649. doi:10.1111/bph.12862 [doi]
    Patterson, S., de Kort, M., Irwin, N., Moffett, R. C., Dokter, W. H., Bos, E. S., . . . Flatt, P. R. (2015).,与抗凝血酶III结合戊二糖缀合的长效胰高血糖素样肽-1类似物的药理表征及抗糖尿病活性。, Diabetes, Obesity & Metabolism, 17(8), 760-770. doi:10.1111/dom.12483 [doi]
    Rieyset,J.,Chauvin,M. A.,Durand,A.,Bravard,A.,Laugerette,F.,Michalski,M. C.,&Vidal,H.(2012)。,Reduction of endoplasmic reticulum stress using chemical chaperones or Grp78 overexpression does not protect muscle cells from palmitate-induced insulin resistance.,生物化学和生物物理研究通信,417(1),439-445。DOI:10.1016 / J.BBRC.2011.11.135 [DOI]
    Ngala, R. A., Zaibi, M. S., Langlands, K., Stocker, C. J., Arch, J. R., & Cawthorne, M. A. (2014).,刺激尿嘧啶肌肌和脂肪细胞的葡萄糖摄取5-(4-苯氧基丁氧基)脂肪醛(PAP-1)可以通过KV1.5而不是KV1.3介导。, Peerj, 2, e614. doi:10.7717/peerj.614 [doi]
    Martagon,A. J.,Lin,J.Z.,Cimini,S. L.,韦伯,P.,&Phillips,K. J.(2015)。,The amelioration of hepatic steatosis by thyroid hormone receptor agonists is insufficient to restore insulin sensitivity in ob/ob mice.,plos一个,10(4),e0122987。DOI:10.1371 / journal.pone.0122987 [DOI]
    Wargent, E. T., Zaibi, M. S., Silvestri, C., Hislop, D. C., Stocker, C. J., Stott, C. G., . . . Cawthorne, M. A. (2013).,The cannabinoid delta(9)-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity.,营养和糖尿病,3,E68。DOI:10.1038 / nutd.2013.9 [DOI]

    General studies

    Kim, S. C., Kim, C. K., Axe, D., Cook, A., Lee, M., Li, T., . . . Lee, Y. K. (2014).,All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade., Hepatology (Baltimore, Md.), 59(5), 1750-1760. doi:10.1002/hep.26699 [doi]
    Rezzani, R., Rodella, L. F., Favero, G., Damiani, G., Paganelli, C., & Reiter, R. J. (2014).,用褪黑素衰减NiH3T3皮肤成纤维细胞中的紫外A诱导的改变。,英国皮肤科杂志,170(2),382-391。DOI:10.1111 / BJD.12622 [DOI]
    Wang, X., West, J. A., Murray, A. J., & Griffin, J. L. (2015).,Comprehensive metabolic profiling of age-related mitochondrial dysfunction in the high-fat-fed ob/ob mouse heart., Journal of Proteome Research, 14(7), 2849-2862. doi:10.1021/acs.jproteome.5b00128 [doi]
    Tang, Y., & Chen, A. (2014).,姜黄素消除了先进的糖化末端产物(年龄)对通过中断瘦素信号传导来发散对年龄受体基因表达的发散调控的影响。, Laboratory Investigation; a Journal of Technical Methods and Pathology, 94(5), 503-516. doi:10.1038/labinvest.2014.42 [doi]
    Church, S. J., Begley, P., Kureishy, N., McHarg, S., Bishop, P. N., Bechtold, D. A., . . . Cooper, G. J. (2015).,Deficient copper concentrations in dried-defatted hepatic tissue from ob/ob mice: A potential model for study of defective copper regulation in metabolic liver disease., Biochemical and Biophysical Research Communications, 460(3), 549-554. doi:10.1016/j.bbrc.2015.03.067 [doi]
    Feingold,K. R.,Grunfeld,C.,Heuer,J.G。,Gupta,A.,Cramer,M.,张,T.,。。。Kharitonenkov,A.(2012)。,FGF21通过炎性刺激增加,并保护含有盲素缺陷的OB / OB小鼠免受败血症的毒性。, Endocrinology, 153(6), 2689-2700. doi:10.1210/en.2011-1496 [doi]
    Shabat, Y., Lichtenstein, Y., Zolotarov, L., Ben Ya'acov, A., & Ilan, Y. (2013).,DT56a的肝脏保护作用与天然杀伤T细胞和调节性T细胞的变化有关。,消化系统杂志,14(2),84-92。DOI:10.1111 / 1751-2980.12003 [DOI]
    Procaccini,C.,De Rosa,V.,Galgani,M.,Carbone,F.,Cassano,S.,Greco,D.,。。。Matarese,G。(2012)。,瘦素诱导的MTOR活化定义了控制CD4 +效应T细胞应答的特定分子和转录签名。, Journal of Immunology (Baltimore, Md.: 1950), 189(6), 2941-2953. doi:10.4049/jimmunol.1200935 [doi]
    Raptis, D. A., Fischer, M. A., Graf, R., Nanz, D., Weber, A., Moritz, W., . . . Clavien, P. A. (2012).,MRI: The new reference standard in quantifying hepatic steatosis?,肠,61(1),117-127。DOI:10.1136 / GUTJNL-2011-300155 [DOI]
    Favero, G., Lonati, C., Giugno, L., Castrezzati, S., Rodella, L. F., & Rezzani, R. (2013).,OB / OB小鼠中褪黑素处理的主动脉和预防肥胖相关功能障碍。, Acta Histochemica, 115(8), 783-788. doi:10.1016/j.acthis.2013.02.014 [doi]
    Adar, T., Ben Ya'acov, A., Lalazar, G., Lichtenstein, Y., Nahman, D., Mizrahi, M., . . . Ilan, Y. (2012).,免疫球蛋白G-增强初乳的口服施用减轻了胰岛素抵抗和肝损伤,并且与天然杀伤T细胞的改变有关。, Clinical and Experimental Immunology, 167(2), 252-260. doi:10.1111/j.1365-2249.2011.04511.x [doi]
    Bastianini, S., Berteotti, C., Gabrielli, A., Del Vecchio, F., Amici, R., Alexandre, C., . . . Zoccoli, G. (2014).,SCOPRISM: A new algorithm for automatic sleep scoring in mice.,中国神经科学方法,235,277-284。DOI:10.1016 / J.Jneumeth.2014.07.018 [DOI]
    Chung, H. K., Kim, Y. K., Park, J. H., Ryu, M. J., Chang, J. Y., Hwang, J. H., . . . Shong, M. (2015).,吲哚衍生物Necrox-7通过抑制线粒体ROS / RNS和炎症来改善OB / OB小鼠的非酒精性脂肪肝炎。, Liver International : Official Journal of the International Association for the Study of the Liver, 35(4), 1341-1353. doi:10.1111/liv.12741 [doi]

    营养

    Reynolds,C. M.,Toomey,S.,McBride,R.,麦克林,J.,Morine,M.J.,Belton,O.,。。。Roche,H. M.(2013)。,Divergent effects of a CLA-enriched beef diet on metabolic health in ApoE-/- and ob/ob mice.,营养生物化学杂志,24(2),401-411。DOI:10.1016 / J.JNUTBIO.2011.12.006 [DOI]

    肥胖

    Agabiti-Rosei, C., De Ciuceis, C., Rossini, C., Porteri, E., Rodella, L. F., Withers, S. B., . . . Rezzani, R. (2014).,Anticontractile activity of perivascular fat in obese mice and the effect of long-term treatment with melatonin.,《超tension, 32(6), 1264-1274. doi:10.1097/HJH.0000000000000178 [doi]
    Rodriguez, A., Becerril, S., Mendez-Gimenez, L., Ramirez, B., Sainz, N., Catalan, V., . . . Fruhbeck, G. (2015).,瘦素给药通过一氧化氮依赖性机制激活Irisin诱导的肌内生成,但降低了对小鼠皮下脂肪褐变的影响。, International Journal of Obesity (2005), 39(3), 397-407. doi:10.1038/ijo.2014.166 [doi]
    Gabriel, T. L., Tol, M. J., Ottenhof, R., van Roomen, C., Aten, J., Claessen, N., . . . van Eijk, M. (2014).,肥胖脂肪组织巨噬细胞的溶酶体应激有助于MITF依赖性GPNMB诱导。, Diabetes, 63(10), 3310-3323. doi:10.2337/db13-1720 [doi]
    Lustig, Y., Barhod, E., Ashwal-Fluss, R., Gordin, R., Shomron, N., Baruch-Umansky, K., . . . Kanety, H. (2014).,RNA结合蛋白PTB和MicroRNA-221 Coregulate Adipor1平移和脂联素信号传导。,糖尿病,63(2),433-445。DOI:10.2337 / dB13-1032 [DOI]