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    ADMET

    Fuchs, Holger; Kishimoto, Wataru; Gansser, Dietmar; Tanswell, Paul; Ishiguro, Naoki;,Brain penetration of WEB 2086 (Apafant) and dantrolene in Mdr1a (P-glycoprotein) and Bcrp knockout rats., Drug metabolism and disposition: the biological fate of chemicals Vol.42, 2014
    Suzuki, Motoya; Komura, Hiroshi; Yoshikawa, Tomonori; Enya, Seiji; Nagao, Akemi; Takubo, Hiroaki; Kogayu, Motohiro;,Characterization of gastrointestinal absorption of digoxin involving influx and efflux transporter in rats: application of mdr1a knockout (-/-) rats into absorption study of multiple transporter substrate., Xenobiotica; the fate of foreign compounds in biological systems Vol.44, 2014
    Zamek-Gliszczynski, Maciej J; Bedwell, David W; Bao, Jing Q; Higgins, J William;,Characterization of SAGE Mdr1a (P-gp), Bcrp, and Mrp2 knockout rats using loperamide, paclitaxel, sulfasalazine, and carboxydichlorofluorescein pharmacokinetics., Drug metabolism and disposition: the biological fate of chemicals Vol.40, 2012
    Huang, Liyue; Li, Xingwen; Roberts, Jonathan; Janosky, Brett; Lin, Min-Hwa Jasmine;,微分22和乳房的作用cer resistance protein in drug distribution into brain, CSF and peripheral nerve tissues in rats., Xenobiotica; the fate of foreign compounds in biological systems Vol.45, 2015
    Miyake, Taiji;,Estimating Efflux Transporter-Mediated Disposition of Molecules beyond the Rule of Five (bRo5) Using Transporter Gene Knockout Rats., Biological & pharmaceutical bulletin Vol.43, 2020
    Fujii, Shinobu; Setoguchi, Chikako; Kawazu, Kouichi; Hosoya, Ken-ichi;,Functional Characterization of Carrier-Mediated Transport of Pravastatin across the Blood-Retinal Barrier in Rats., Drug metabolism and disposition: the biological fate of chemicals Vol.43, 2015
    Fujii, Shinobu; Setoguchi, Chikako; Kawazu, Kouichi; Hosoya, Ken-ichi;,Impact of P-glycoprotein on blood-retinal barrier permeability: comparison of blood-aqueous humor and blood-brain barrier using mdr1a knockout rats., Investigative ophthalmology & visual science Vol.55, 2014
    Dumas, Noé; Moulin-Sallanon, Marcelle; Fender, Pascal; Tournier, Benjamin B; Ginovart, Nathalie; Charnay, Yves; Millet, Philippe;,In Vivo Quantification of 5-HT2A Brain Receptors in Mdr1a KO Rats with 123I-R91150 Single-Photon Emission Computed Tomography., Molecular imaging Vol.14, 2015
    Sato, Sho; Tohyama, Kimio; Kosugi, Yohei;,Investigation of MDR1-overexpressing cell lines to derive a quantitative prediction approach for brain disposition using in vitro efflux activities., European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Vol.142, 2020
    Nagaya, Yoko; Nozaki, Yoshitane; Takenaka, Osamu; Watari, Ryuji; Kusano, Kazutomi; Yoshimura, Tsutomu; Kusuhara, Hiroyuki;,Investigation of utility of cerebrospinal fluid drug concentration as a surrogate for interstitial fluid concentration using microdialysis coupled with cisternal cerebrospinal fluid sampling in wild-type and Mdr1a(-/-) rats., Drug metabolism and pharmacokinetics Vol.31, 2016
    Ganguly, Samit; Panetta, John C; Roberts, Jessica K; Schuetz, Erin G;,Ketamine Pharmacokinetics and Pharmacodynamics Are Altered by P-Glycoprotein and Breast Cancer Resistance Protein Efflux Transporters in Mice., Drug metabolism and disposition: the biological fate of chemicals Vol.46, 2018
    Zamek-Gliszczynski, Maciej J; Goldstein, Keith M; Paulman, April; Baker, Thomas K; Ryan, Timothy P;,Minor compensatory changes in SAGE Mdr1a (P-gp), Bcrp, and Mrp2 knockout rats do not detract from their utility in the study of transporter-mediated pharmacokinetics., Drug metabolism and disposition: the biological fate of chemicals Vol.41, 2013
    Al-Ali, Ahmed A Abdulhussein; Quach, Jeffrey Rong Chao; Bundgaard, Christoffer; Steffansen, Bente; Holm, René; Nielsen, Carsten Uhd;,Polysorbate 20 alters the oral bioavailability of etoposide in wild type and mdr1a deficient Sprague-Dawley rats., International journal of pharmaceutics Vol.543, 2018
    Nielsen, Carsten Uhd; Abdulhussein, Ahmed A; Colak, Dilan; Holm, René;,Polysorbate 20 increases oral absorption of digoxin in wild-type Sprague Dawley rats, but not in mdr1a(-/-) Sprague Dawley rats., International journal of pharmaceutics Vol.513, 2016
    Nicolas, Jean-Marie; Chanteux, Hugues; Nicolaï, Johan; Brouta, Frédéric; Viot, Delphine; Rosseels, Marie-Luce; Gillent, Eric; Bonnaillie, Pierre; Mathy, François-Xavier; Long, Jeff; Helmer, Eric;,Role of P-glycoprotein in the brain disposition of seletalisib: Evaluation of the potential for drug-drug interactions., European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Vol.142, 2020
    Dulin, Jennifer N; Moore, Meredith L; Grill, Raymond J;,The dual cyclooxygenase/5-lipoxygenase inhibitor licofelone attenuates p-glycoprotein-mediated drug resistance in the injured spinal cord., Journal of neurotrauma Vol.30, 2013
    Liu, Xingrong; Cheong, Jonathan; Ding, Xiao; Deshmukh, Gauri;,Use of cassette dosing approach to examine the effects of P-glycoprotein on the brain and cerebrospinal fluid concentrations in wild-type and P-glycoprotein knockout rats., Drug metabolism and disposition: the biological fate of chemicals Vol.42, 2014
    Chiang M, Back HM, Lee JB, Oh S, Guo T, Girgis S, Park C, Haroutounian S, Kagan L.,Pharmacokinetic Modeling of the Impact of P-glycoprotein on Ondansetron Disposition in the Central Nervous System, Pharm Res. 2020 Sep 28;37(10):205. doi: 10.1007/s11095-020-02929-2.
    Tsartsalis S, Tournier BB, Millet P.,In vivo absolute quantification of striatal and extrastriatal D(2/3) receptors with [(123)I]epidepride SPECT, EJNMMI Res. 2020 Jun 16;10(1):66. doi: 10.1186/s13550-020-00650-0.