St Andre, Michael; Johnson, Mark; Bansal, Prashant N; Wellen, Jeremy; Robertson, Andrew; Opsahl, Alan; Burch, Peter M; Bialek, Peter; Morris, Carl;,
A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys，骨骼肌Vol.7，2017年
Barfield RM, Kim YC, Chuprakov S, Zhang F, Bauzon M, Ogunkoya AO, Yeo D, Hickle C, Pegram MD, Rabuka D, Drake PM.,
A Novel HER2-targeted Antibody-drug Conjugate Offers the Possibility of Clinical Dosing at Trastuzumab-equivalent Exposure Levels, Mol Cancer Ther. 2020 Sep;19(9):1866-1874. doi: 10.1158/1535-7163.MCT-20-0190. Epub 2020 Jul 10.
史密斯，埃里克j;奥尔森，卡拉;Haber，Lauric J;varghese，bindu;Duramad，Paurene;Tustian，Andrew D;伊伊妮德，阿德莱坎;吉斯卡·克莱斯卡;Canova，Lauren;Menon，Jayanthi; Principio, Jennifer; MacDonald, Douglas; Kantrowitz, Joel; Papadopoulos, Nicholas; Stahl, Neil; Yancopoulos, George D; Thurston, Gavin; Davis, Samuel;,
一部小说,本机-format bispecific antibody triggering T-cell killing of B-cells is robustly active in mouse tumor models and cynomolgus monkeys., Scientific reports Vol.5, 2015
Elliott AG, Huang JX, Neve S, Zuegg J, Edwards IA, Cain AK, Boinett CJ, Barquist L, Lundberg CV, Steen J, Butler MS, Mobli M, Porter KM, Blaskovich MAT, Lociuro S, Strandh M, Cooper MA.,
具有抗生素活性对多药抗革兰氏阴性细菌的两性疗法，Nat Communce。2020年6月23日; 11（1）：3184。DOI：10.1038 / s41467-020-16950-x。
Sainson RCA, Thotakura AK, Kosmac M, Borhis G, Parveen N, Kimber R, Carvalho J, Henderson SJ, Pryke KL, Okell T, O'Leary S, Ball S, Van Krinks C, Gamand L, Taggart E, Pring EJ, Ali H, Craig H, Wong VWY, Liang Q, Rowlands RJ, Lecointre M, Campbell J, Kirby I, Melvin D, Germaschewski V, Oelmann E, Quaratino S, McCourt M.,
An Antibody Targeting ICOS Increases Intratumoral Cytotoxic to Regulatory T-cell Ratio and Induces Tumor Regression，癌症免疫res。2020年12月8日（12）：1568-1582。DOI：10.1158 / 2326-6066.CIR-20-0034。EPUB 2020 SEP 30。
Vahle, John L; Byrd, Richard A; Blackbourne, Jamie L; Martin, Jennifer A; Sorden, Steven D; Ryan, Thomas; Pienkowski, Thomas; Wijsman, John A; Smith, Holly W; Rosol, Thomas J;,
杜拉格兰蛋白质对雄性猴子甲状腺C细胞和血清降钙素的影响, Endocrinology Vol.156, 2015
Frederick A, Sullivan J, Liu L, Adamowicz M, Lukason M, Raymer J, Luo Z, Jin X, Rao KN, O'Riordan C.,
工程化衣壳用于高效的基因递送至视网膜和角膜，嗡嗡声基因。2020 Jul;31(13-14):756-774. doi: 10.1089/hum.2020.070.
Almholt K, Wang J, Pass J, Røder G, Padkjær SB, Hebsgaard JB, Xia W, Yang L, Forsell J, Breinholt VM, Thygesen P, Agersø H, Loftager M, Usher PA.,
Identification and preclinical development of an anti-proteolytic uPA antibody for rheumatoid arthritis, J Mol Med (Berl). 2020 Apr;98(4):585-593. doi: 10.1007/s00109-020-01889-9. Epub 2020 Feb 27.
Laffan SB, Thomson AS, Mai S, Fishman C, Kambara T, Nistala K, Raymond JT, Chen S, Ramani T, Pageon L, Polsky R, Watkins M, Ottolangui G, White JR, Maier C, Herdman M, Bouma G.,
Immune complex disease in a chronic monkey study with a humanised, therapeutic antibody against CCL20 is associated with complement-containing drug aggregates, PLoS One. 2020 Apr 23;15(4):e0231655. doi: 10.1371/journal.pone.0231655. eCollection 2020.
Damann N, Bahrenberg G, Stockhausen H, Habermann CJ, Lesch B, Frank-Foltyn R, Lee J, Ann J, Christoph T.,
体外表征热中性的交易nsient receptor potential vanilloid-1 (TRPV1) inhibitor GRTE16523, Eur J Pharmacol. 2020 Mar 15;871:172934. doi: 10.1016/j.ejphar.2020.172934. Epub 2020 Jan 16.
Datta-Mannan A, Estwick S, Zhou C, Choi H, Douglass NE, Witcher DR, Lu J, Beidler C, Millican R.,
生理化学性质对单克隆抗体皮下吸收和生物利用度的影响，mabs。2020年1月1日; 12（1）：1770028。DOI：10.1080 / 19420862.2020.1770028。
Bennett G, Brown A, Mudd G, Huxley P, Van Rietschoten K, Pavan S, Chen L, Watcham S, Lahdenranta J, Keen N.,
MMAE Delivery Using the Bicycle Toxin Conjugate BT5528, Mol Cancer Ther. 2020 Jul;19(7):1385-1394. doi: 10.1158/1535-7163.MCT-19-1092. Epub 2020 May 12.
Del Balzo U, Signore PE, Walkinshaw G, Seeley TW, Brenner MC, Wang Q, Guo G, Arend MP, Flippin LA, Chow FA, Gervasi DC, Kjaergaard CH, Langsetmo I, Guenzler V, Liu DY, Klaus SJ, Lin A, Neff TB.,
Nonclinical Characterization of the Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat, a Novel Treatment of Anemia of Chronic Kidney Disease，J pharmacol exp ther。2020 8月; 374（2）：342-353。DOI：10.1124 / jpet.120.265181。EPUB 2020 6月2日。
Yamamoto BJ, Shadiack AM, Carpenter S, Sanford D, Henning LN, Gonzales N, O'Connor E, Casey LS, Serbina NV,
Obiltoxaximab Prevents Disseminated Bacillus anthracis Infection and Improves Survival during Pre- and Postexposure Prophylaxis in Animal Models of Inhalational Anthrax., Antimicrob Agents Chemother. 2016 Sep 23;60(10):5796-805.
Liu J, Xavy S, Mihardja S, Chen S, Sompalli K, Feng D, Choi T, Agoram B, Majeti R, Weissman IL, Volkmer JP.,
Targeting macrophage checkpoint inhibitor SIRPα for anticancer therapy, JCI Insight. 2020 Jun 18;5(12):e134728. doi: 10.1172/jci.insight.134728.
