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    Cellular therapies

    Nowak-Imialek M, Wunderlich S, Herrmann D, Breitschuh-Leibling S, Gohring G, Petersen B, Klein S, Baulain U, Lucas-Hahn A, Martin U, Niemann H.,In Vitro and In Vivo Interspecies Chimera Assay Using Early Pig Embryos细胞重新编程。2020年6月,22(3):118 - 133。doi: 10。1089/cell.2019.0107. Epub 2020 May 19.

    COVID-19

    Finch Cl,Crozier I,Lee Jh,Byrum R,Cooper Tk,Liang J,Sharer K,Solomon J,Sayre PJ,Kocher G,Bartos C,AiOSA NM,Castro M,Larson Pa,Adams R,Beitzel B,Di Paolan,kugelman jr,kurtzjr,burdette t,纳森mc,feuerstein im,palacios g,圣克莱尔mc,缺乏史密斯·米格,约翰逊rf,braun km,ramuta md,wada j,schmaljohn cs,friedrich tc,o'connor dh,kuhn jh。,Characteristic and quantifiable COVID-19-like abnormalities in CT- and PET/CT-imaged lungs of SARS-CoV-2-infected crab-eating macaques (Macaca fascicularis),Biorxiv。2020 May 14:2020.05.14.096727. doi: 10.1101/2020.05.14.096727. Preprint.
    Baisa G, Rancour D, Mansfield K, Burns M, Martin L, Cunha D, Fischer J, Muecksch F, Hatziioannou T, Bieniasz P, Schomburg F, Luke K.,重组蛋白SARS-COV-2候选疫苗引发猕猴的高滴度中和抗体,Biorxiv。2020年12月21:2020.12.20.422693。DOI:10.1101 / 2020.12.20.422693。预印刷品。

    Diabetes

    Vahle, John L; Byrd, Richard A; Blackbourne, Jamie L; Martin, Jennifer A; Sorden, Steven D; Ryan, Thomas; Pienkowski, Thomas; Rosol, Thomas J; Snyder, Paul W; Klöppel, Günter;,Effects of the GLP-1 Receptor Agonist Dulaglutide on the Structure of the Exocrine Pancreas of Cynomolgus Monkeys.,毒理学病理Vol.43,2015
    Levy,至理名言E;Jodka,卡洛琳米;任,广州市史蒂夫n; Mamedova, Lala; Sharma, Abhinandini; Samant, Manoj; DSouza, Lawrence J; Soares, Christopher J; Yuskin, Diane R; Jin, Li Jenny; Parkes, David G; Tatarkiewicz, Krystyna; Ghosh, Soumitra S,具有肽白蛋白结合结构域的新型杂氮类似物:具有延长的作用持续时间的有效的抗糖尿病药。, PloS one Vol.9, 2014
    Kolumam,Ganesh;陈,马克Z;佟,雷蒙德;Zavala-Solorio,何塞;凯斯,兰斯;瓦尔巴拉斯梵蒂巴斯;罗斯,杰德;Wyatt,Shelby K;Gandham,Vineela D;Carano,Richard A D; Dunshee, Diana Ronai; Wu, Ai-Luen; Haley, Benjamin; Anderson, Keith; Warming, Søren; Rairdan, Xin Y; Lewin-Koh, Nicholas; Zhang, Yingnan; Gutierrez, Johnny; Baruch, Amos; Gelzleichter, Thomas R; Stevens, Dale; Rajan, Sharmila; Bainbridge, Travis W; Vernes, Jean-Michel; Meng, Y Gloria; Ziai, James; Soriano, Robert H; Brauer, Matthew J; Chen, Yongmei; Stawicki, Scott; Kim, Hok Seon; Comps-Agrar, Laëtitia; Luis, Elizabeth; Spiess, Christoph; Wu, Yan; Ernst, James A; McGuinness, Owen P; Peterson, Andrew S; Sonoda, Junichiro;,通过人源化双特异性抗体激动剂进行成纤维细胞生长因子受体1的持续棕色脂肪刺激和胰岛素敏化.Klotho复合物, EBioMedicine Vol.2, 2015

    一般性研究

    Le, Kha N; Gibiansky, Leonid; Good, Jeremy; Davancaze, Teresa; van Lookeren Campagne, Menno; Loyet, Kelly M; Morimoto, Alyssa; Jin, Jin; Damico-Beyer, Lisa A; Hanley, William D;,Lampalizumab治疗地理萎缩的CynoMolgus猴子因子D抑制因子D抑制的机械药效/药效模型。,药理学与实验治疗杂志Vol.355,2015
    Datta-Mannan,Amita;宽松,约翰尼e;菩提树菩提树;Torgerson,Stacy;Breyer,Matthew;Wrooblewski,Victor J;,Aberrant bispecific antibody pharmacokinetics linked to liver sinusoidal endothelium clearance mechanism in cynomolgus monkeys, mAbs Vol.8, 2016
    Heenen,Jonathan R;jennifer rojko;埃文斯,马克;棕色,汤姆p;Bobrowski,Walter F;Vitsky,Allison;达纳尔顿;Tripathi,Niraj;Bollini,Sangeetha Subbarao;约翰逊,西奥多; Lin, John C; Khan, Nasir; Han, Bora;,Characterization, biomarkers, and reversibility of a monoclonal antibody-induced immune complex disease in cynomolgus monkeys (Macaca fascicularis)., Toxicologic pathology Vol.42, 2014
    Cirimotich, Chris M; Vela, Eric M; Garver, Jennifer; Barnewall, Roy E; Miller, Brian D; Meister, Gabriel T; Rogers, James V;,皮卡隆ya病毒感染在内皮和气溶胶暴露之后的猕猴桃。, Virology journal Vol.14, 2017
    Grant-Klein, Rebecca J; Altamura, Louis A; Badger, Catherine V; Bounds, Callie E; Van Deusen, Nicole M; Kwilas, Steven A; Vu, Hong A; Warfield, Kelly L; Hooper, Jay W; Hannaman, Drew; Dupuy, Lesley C; Schmaljohn, Connie S;,Codon-optimized filovirus DNA vaccines delivered by intramuscular electroporation protect cynomolgus macaques from lethal Ebola and Marburg virus challenges., Human vaccines & immunotherapeutics Vol.11, 2015
    Bantseev, Vladimir; Miller, Paul E; Nork, T Michael; Rasmussen, Carol A; McKenzie, Aija; Christian, Brian J; Booler, Helen; Thackaberry, Evan A;,Determination of a No Observable Effect Level for Endotoxin Following a Single Intravitreal Administration to Cynomolgus Monkeys.,眼科医生和治疗学杂志:官方药理学与治疗型股份有限公司Vol.35,2019
    Phuah, Jiayao; Wong, Eileen A; Gideon, Hannah P; Maiello, Pauline; Coleman, M Teresa; Hendricks, Matthew R; Ruden, Rachel; Cirrincione, Lauren R; Chan, John; Lin, Philana Ling; Flynn, JoAnne L;,Effects of B Cell Depletion on Early Mycobacterium tuberculosis Infection in Cynomolgus Macaques., Infection and immunity Vol.84, 2016
    Malkevich, Nina V; Hopkins, Robert J; Bernton, Edward; Meister, Gabriel T; Vela, Eric M; Atiee, George; Johnson, Virginia; Nabors, Gary S; Aimes, Ronald T; Ionin, Boris; Skiadopoulos, Mario H;,AVP-21d9,炭疽单克隆抗体,动物模型和人类的疗效和安全性。, . Antimicrobial agents and chemotherapy Vol.58, 2014
    邓树,戴安娜罗奈;Bainbridge,Travis W;Kljavin, Noelyn M; Zavala-Solorio, Jose; Schroeder, Amy C; Chan, Ruby; Corpuz, Racquel; Wong, Manda; Zhou, Wei; Deshmukh, Gauri; Ly, Justin; Sutherlin, Daniel P; Ernst, James A; Sonoda, Junichiro;,Fibroblast Activation Protein Cleaves and Inactivates Fibroblast Growth Factor 21.,生物化学杂志Vol.291,2016
    厄丽莎白紫星;Solonets,Maria;奥拉夫库尔曼;希克,埃格内德;吹笛者 - Lepoutre,汉娜;歌手,托马斯;Tyagi,Gaurav;,对Cynomolgus猴子的超敏感性反应,与人类的相关性。, Toxicologic pathology Vol.45, 2017
    赫特,朱莉;洛夫齐克,朱莉;Drysdale,梅丽莎; Sherwood, Robert L; Brasel, Trevor; Lipscomb, Mary F; Lyons, C Rick;,Lethal factor, but not edema factor, is required to cause fatal anthrax in cynomolgus macaques after pulmonary spore challenge., The American journal of pathology Vol.184, 2014
    Quinet,Elaine M;贝索,迈克尔D;Halpern,Anita R;Yates,David W;Steffan,Robert J;职员,瓦莱丽;Resmini,Christine;基思,詹姆斯C;Berrodin,Thomas J;Feingold,Irene; Zhong, Wenyan; Hartman, Helen B; Evans, Mark J; Gardell, Stephen J; DiBlasio-Smith, Elizabeth; Mounts, William M; LaVallie, Edward R; Wrobel, Jay; Nambi, Ponnal; Vlasuk, George P,LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse., Journal of lipid research Vol.50, 2009
    Alfson, Kendra J; Avena, Laura E; Beadles, Michael W; Staples, Hilary; Nunneley, Jerritt W; Ticer, Anysha; Dick, Edward J; Owston, Michael A; Reed, Christopher; Patterson, Jean L; Carrion, Ricardo; Griffiths, Anthony;,Particle-to-PFU ratio of Ebola virus influences disease course and survival in cynomolgus macaques,病毒学杂志Vol.89,2015
    Mitchell, Andrea Z; McMahon, Carrie; Beck, Tom W; Sarazan, R Dustan,Sensitivity of two noninvasive blood pressure measurement techniques compared to telemetry in cynomolgus monkeys and beagle dogs, Journal of pharmacological and toxicological methods Vol.62,
    Buse, Eberhard; Häeger, Jan-Dirk; Svensson-Arvelund, Judit; Markert, Udo R; Faas, Marijke M; Ernerudh, Jan; Dixon, Darlene; Cline, J Mark; Pfarrer, Christiane;,The placenta in toxicology. Part I: Animal models in toxicology: placental morphology and tolerance molecules in the cynomolgus monkey (Macaca fascicularis)., Toxicologic pathology Vol.42, 2014
    Hoffmann, Peter; Bentley, Phil; Sahota, Pritam; Schoenfeld, Heidi; Martin, Lori; Longo, Linda; Spaet, Robert; Moulin, Pierre; Pantano, Serafino; Dubost, Valerie; Lapadula, Dan; Burkey, Bryan; Kaushik, Virendar; Zhou, Wei; Hayes, Michael; Flavahan, Nick; Chibout, Salah-Dine; Busch, Steve;,Vildagliptin诱导的Cynomolgus猴的血管血管诱导的皮肤效应:外周交感神经系统和神经肽的病理机制作用, Toxicologic pathology Vol.42, 2014

    免疫学

    Vitale LA, He LZ, Thomas LJ, Wasiuk A, O'Neill T, Widger J, Crocker A, Mills-Chen L, Forsberg E, Weidlick J, Patterson C, Hammond RA, Boyer J, Sisson C, Alvarado D, Goldstein J, Marsh HC Jr, Keler T.,CDX-527的开发:一种双特异性抗体,组合PD-1封闭和CD27癌症免疫疗法的共刺激, Cancer Immunol Immunother. 2020 Oct;69(10):2125-2137. doi: 10.1007/s00262-020-02610-y. Epub 2020 May 25.
    Sivko, G S; Stark, G V; Tordoff, K P; Taylor, K L; Glaze, E; VanRaden, M; Schiffer, J M; Hewitt, J A; Quinn, C P; Nuzum, E O;,Evaluation of early immune response-survival relationship in cynomolgus macaques after Anthrax Vaccine Adsorbed vaccination and Bacillus anthracis spore challenge, Vaccine Vol.34, 2016
    Latuszek A, Liu Y, Olsen O, Foster R, Cao M, Lovric I, Yuan M, Liu N, Chen H, Zhang Q, Xiao H, Springer C, Ehrlich G, Kamat V, Rafique A, Hu Y, Krueger P, Huang T, Poueymirou W, Babb R, Rosconi MP, Retter MW, Chen G, Morton L, Zambrowicz B, Cao J, Romano C, Olson WC.,Inhibition of complement pathway activation with Pozelimab, a fully human antibody to complement component C5,plos一个。2020 May 8;15(5):e0231892. doi: 10.1371/journal.pone.0231892. eCollection 2020.
    Gideon, Hannah P; Phuah, Jiayao; Junecko, Beth A; Mattila, Joshua T;,Neutrophils express pro- and anti-inflammatory cytokines in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques., Mucosal immunology Vol.12, 2019
    伊利伊利伊利;Moine,Valéry;培养器,露西洛;Salgado-Pires,Susana;约翰逊,Zoë;帕帕诺南诺,安妮;劳拉;Calloud,Sébastien;Majocchi,Stefano;纳尔逊,罗伯特; Rousseau, François; Ferlin, Walter; Kosco-Vilbois, Marie; Fischer, Nicolas; Masternak, Krzysztof;,Selective Blockade of the Ubiquitous Checkpoint Receptor CD47 Is Enabled by Dual-Targeting Bispecific Antibodies., Molecular therapy : the journal of the American Society of Gene Therapy Vol.25, 2017

    传染病

    Baisa G, Rancour D, Mansfield K, Burns M, Martin L, Cunha D, Fischer J, Muecksch F, Hatziioannou T, Bieniasz P, Schomburg F, Luke K.,重组蛋白SARS-COV-2候选疫苗引发猕猴的高滴度中和抗体,Biorxiv。2020年12月21:2020.12.20.422693。DOI:10.1101 / 2020.12.20.422693。预印刷品。
    Finch Cl,Crozier I,Lee Jh,Byrum R,Cooper Tk,Liang J,Sharer K,Solomon J,Sayre PJ,Kocher G,Bartos C,AiOSA NM,Castro M,Larson Pa,Adams R,Beitzel B,Di Paolan,kugelman jr,kurtzjr,burdette t,纳森mc,feuerstein im,palacios g,圣克莱尔mc,缺乏史密斯·米格,约翰逊rf,braun km,ramuta md,wada j,schmaljohn cs,friedrich tc,o'connor dh,kuhn jh。,Characteristic and quantifiable COVID-19-like abnormalities in CT- and PET/CT-imaged lungs of SARS-CoV-2-infected crab-eating macaques (Macaca fascicularis),Biorxiv。2020 May 14:2020.05.14.096727. doi: 10.1101/2020.05.14.096727. Preprint.

    神经科学

    Takemura H,Palomero-Gallagher N,Axer M,Gräßeld,Jorgensen MJ,Woods R,Zilles K.,远程猴子视觉系统中微米纤维捆绑的神经纤维束的解剖学,elife。2020 8月26日; 9:E55444。DOI:10.7554 / Elife.55444。
    Niu M, Impieri D, Rapan L, Funck T, Palomero-Gallagher N, Zilles K.,Receptor-driven, multimodal mapping of cortical areas in the macaque monkey intraparietal sulcus,elife。2020 Jul 2;9:e55979. doi: 10.7554/eLife.55979.

    Obesity

    Yang, Linda; Chang, Chih-Chuan; Sun, Zhe; Madsen, Dennis; Zhu, Haisun; Padkjær, Søren B; Wu, Xiaoai; Huang, Tao; Hultman, Karin; Paulsen, Sarah J; Wang, Jishu; Bugge, Anne; Frantzen, Jane Boesen; Nørgaard, Per; Jeppesen, Jacob Fuglsbjerg; Yang, Zhiru; Secher, Anna; Chen, Haibin; Li, Xun; John, Linu Mary; Shan, Bing; He, Zhenhua; Gao, Xiang; Su, Jing; Hansen, Kristian T; Yang, Wei; Jørgensen, Sebastian Beck;,Gfral是GDF15的受体,是配体的抗肥胖作用所必需的。, Nature medicine Vol.23, 2017

    药理

    St Andre, Michael; Johnson, Mark; Bansal, Prashant N; Wellen, Jeremy; Robertson, Andrew; Opsahl, Alan; Burch, Peter M; Bialek, Peter; Morris, Carl;,A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys,骨骼肌Vol.7,2017年
    Barfield Rm,Kim YC,Chuprakov S,Zhang F,Bauzon M,Ogunkoya AO,Yeo D,Hickle C,PEGram MD,Rabuka D,Drake Pm。,A Novel HER2-targeted Antibody-drug Conjugate Offers the Possibility of Clinical Dosing at Trastuzumab-equivalent Exposure Levels,莫癌。2020年9月19日(9):1866-1874。DOI:10.1158 / 1535-7163.mct-20-0190。EPUB 2020 JUL 10。
    史密斯,Eric J。奥尔森,卡拉;哈伯,月桂J;Varghese, Bindu; Duramad, Paurene; Tustian, Andrew D; Oyejide, Adelekan; Kirshner, Jessica R; Canova, Lauren; Menon, Jayanthi; Principio, Jennifer; MacDonald, Douglas; Kantrowitz, Joel; Papadopoulos, Nicholas; Stahl, Neil; Yancopoulos, George D; Thurston, Gavin; Davis, Samuel;,在小鼠肿瘤模型和鱼糜猴中,触发T细胞杀伤B细胞的T细胞杀伤B细胞的新的抗特异性抗体。, Scientific reports Vol.5, 2015
    Elliott AG, Huang JX, Neve S, Zuegg J, Edwards IA, Cain AK, Boinett CJ, Barquist L, Lundberg CV, Steen J, Butler MS, Mobli M, Porter KM, Blaskovich MAT, Lociuro S, Strandh M, Cooper MA.,An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria, Nat Commun. 2020 Jun 23;11(1):3184. doi: 10.1038/s41467-020-16950-x.
    Sainson RCA,Thotakura Ak,Kosmac M,Borhis G,Parveen N,Kimber R,Carvalho J,Henderson SJ,Pryke KL,Okell T,O'Leary S,Ball S,Van Krinks C,Gamand L,Taggart E,Pring EJ,Ali H,Craig H,Wong Vwy,Liang Q,Roclands RJ,LecoIntre M,Campbell J,Kirby I,Melvin D,Germaschewski V,Oelmann E,Qualatino S,McCourt M.,An Antibody Targeting ICOS Increases Intratumoral Cytotoxic to Regulatory T-cell Ratio and Induces Tumor Regression, Cancer Immunol Res. 2020 Dec;8(12):1568-1582. doi: 10.1158/2326-6066.CIR-20-0034. Epub 2020 Sep 30.
    Nagy CF,Mondick J,Serbina N,Casey LS,Carpenter Se,法国J,Guttendorf R.,对美国FDA动物规则治疗吸入性炭疽病的动物对人体剂量翻译。, Clin Transl Sci. 2017 Jan;10(1):12-19.
    卡特QL,Siegel Rw,Qian Y,Konrad RJ。,Application of a novel drug-tolerant target assay for measuring target engagement when only one epitope remains after therapeutic antibodies bind their targets, J Immunol Methods. 2021 Feb;489:112916. doi: 10.1016/j.jim.2020.112916. Epub 2020 Nov 23.
    Lin, Cheng-Wen; Sherman, Bryan; Moore, Lori A; Laethem, Carmen L; Lu, Da-Wen; Pattabiraman, Padmanabhan P; Rao, Ponugoti Vasantha; deLong, Mitchell A; Kopczynski, Casey C;,Discovery and Preclinical Development of Netarsudil, a Novel Ocular Hypotensive Agent for the Treatment of Glaucoma.,眼科医生和治疗学杂志:官方药理学与治疗型股份有序杂志Vol.34,
    Shen J, Moats RA, Pollack HA, Robinson MR, Attar M.,单一内胞胎施用后(14)C-拉扎斯托的分布与重复的局部给药, Ophthalmol Ther. 2020 Dec;9(4):929-940. doi: 10.1007/s40123-020-00285-3. Epub 2020 Aug 1.
    Vahle, John L; Byrd, Richard A; Blackbourne, Jamie L; Martin, Jennifer A; Sorden, Steven D; Ryan, Thomas; Pienkowski, Thomas; Wijsman, John A; Smith, Holly W; Rosol, Thomas J;,杜拉格兰蛋白质对雄性猴子甲状腺C细胞和血清降钙素的影响, Endocrinology Vol.156, 2015
    Russo,Andrew T;甘格拉斯,道格拉斯·瓦;野蛮人,trevor l;贝克,罗伯特o;Cawthon,Andrew G;雷诺兹,艾琳;贝利,塔拉;Kuehl,Philip J;苏格塔,维多利亚;agans,克里斯特勒; Hruby, Dennis E;,治疗延迟对致致致致致致致致致死猕猴Keakques致病症症术后致致致死的疗效。,传染病杂志Vol.218,2018年
    Shearer JD,Henning L,Sanford DC,Li N,Skiadopoulos MH,Reece JJ,Ionin B,Savransky V.,Efficacy of the AV7909 anthrax vaccine candidate in guinea pigs and nonhuman primates following two immunizations two weeks apart, Vaccine. 2021 Jan 3;39(1):1-5. doi: 10.1016/j.vaccine.2020.10.095. Epub 2020 Nov 13.
    Yamamoto BJ,Shadiacon Am,Carpenter S,Sanford D,Henning Ln,O'Connor E,冈州尼,Mondick J,法国J,Stark GV,Fisher AC,Casey LS,Serbina NV。,Efficacy Projection of Obiltoxaximab for Treatment of Inhalational Anthrax across a Range of Disease Severity. Antimicrob Agents Chemother., 2016 Sep 23;60(10):5787-95.
    Frederick A,Sullivan J,Liu L,Adamowicz M,Lukason M,Raymer J,Luo Z,Jin X,Rao Kn,O'riordan C.,Engineered Capsids for Efficient Gene Delivery to the Retina and Cornea,嗡嗡声基因。2020 Jul;31(13-14):756-774. doi: 10.1089/hum.2020.070.
    Almholt K, Wang J, Pass J, Røder G, Padkjær SB, Hebsgaard JB, Xia W, Yang L, Forsell J, Breinholt VM, Thygesen P, Agersø H, Loftager M, Usher PA.,Identification and preclinical development of an anti-proteolytic uPA antibody for rheumatoid arthritis, J Mol Med (Berl). 2020 Apr;98(4):585-593. doi: 10.1007/s00109-020-01889-9. Epub 2020 Feb 27.
    Laffan SB, Thomson AS, Mai S, Fishman C, Kambara T, Nistala K, Raymond JT, Chen S, Ramani T, Pageon L, Polsky R, Watkins M, Ottolangui G, White JR, Maier C, Herdman M, Bouma G.,Immune complex disease in a chronic monkey study with a humanised, therapeutic antibody against CCL20 is associated with complement-containing drug aggregates,plos一个。2020年4月23日; 15(4):E0231655。DOI:10.1371 / journal.pone.0231655。ecollection 2020。
    Damann N, Bahrenberg G, Stockhausen H, Habermann CJ, Lesch B, Frank-Foltyn R, Lee J, Ann J, Christoph T.,热源瞬态受体潜水过敏 - 1(TRPV1)抑制剂GRTE16523的体外表征, Eur J Pharmacol. 2020 Mar 15;871:172934. doi: 10.1016/j.ejphar.2020.172934. Epub 2020 Jan 16.
    劳伦斯SA,Blankenship R,Brown R,Estwick S,Ellis B,Thangaraju A,Datta-Mannan A.,FCRN结合特性对Fc分子胃肠道吸收和曝光谱的影响,Bioorg Med Chem。2020年12月21日; 32:115942。DOI:10.1016 / J.BMC.2020.115942。在线之前在线。
    Datta-Mannan A, Estwick S, Zhou C, Choi H, Douglass NE, Witcher DR, Lu J, Beidler C, Millican R.,Influence of physiochemical properties on the subcutaneous absorption and bioavailability of monoclonal antibodies, MAbs. 2020 Jan 1;12(1):1770028. doi: 10.1080/19420862.2020.1770028.
    Bennett G, Brown A, Mudd G, Huxley P, Van Rietschoten K, Pavan S, Chen L, Watcham S, Lahdenranta J, Keen N.,MMAE Delivery Using the Bicycle Toxin Conjugate BT5528,莫癌。2020 Jul;19(7):1385-1394. doi: 10.1158/1535-7163.MCT-19-1092. Epub 2020 May 12.
    Del Balzo U, Signore PE, Walkinshaw G, Seeley TW, Brenner MC, Wang Q, Guo G, Arend MP, Flippin LA, Chow FA, Gervasi DC, Kjaergaard CH, Langsetmo I, Guenzler V, Liu DY, Klaus SJ, Lin A, Neff TB.,缺氧诱导因子脯氨酰羟化酶抑制剂Roxadustat的非旋转性表征,一种新型慢性肾病贫血的治疗, J Pharmacol Exp Ther. 2020 Aug;374(2):342-353. doi: 10.1124/jpet.120.265181. Epub 2020 Jun 2.
    Yamamoto BJ, Shadiack AM, Carpenter S, Sanford D, Henning LN, Gonzales N, O'Connor E, Casey LS, Serbina NV,Obiltoxaximab Prevents Disseminated Bacillus anthracis Infection and Improves Survival during Pre- and Postexposure Prophylaxis in Animal Models of Inhalational Anthrax., Antimicrob Agents Chemother. 2016 Sep 23;60(10):5796-805.
    TESS DA,ENG H,Kalgutkar As,Litchfield J,Edmonds DJ,Griffith Da,Varma MVS。,预测酸性和两性离子药物的人类肝脏清除, J Med Chem. 2020 Oct 22;63(20):11831-11844. doi: 10.1021/acs.jmedchem.0c01033. Epub 2020 Oct 9.
    Randolph Jt,voight ea,greszler sn,uno,牛顿jn,gleason公里,Stolarik d,Van Handel C,Bow Daj,Degoey Da。,Prodrug Strategies to Improve the Solubility of the HCV NS5A Inhibitor Pibrentasvir (ABT-530), J Med Chem. 2020 Oct 8;63(19):11034-11044. doi: 10.1021/acs.jmedchem.0c00956. Epub 2020 Sep 17.
    Liu J, Xavy S, Mihardja S, Chen S, Sompalli K, Feng D, Choi T, Agoram B, Majeti R, Weissman IL, Volkmer JP.,Targeting macrophage checkpoint inhibitor SIRPα for anticancer therapy, JCI Insight. 2020 Jun 18;5(12):e134728. doi: 10.1172/jci.insight.134728.
    Kovalova N,Boalles J,Wen Y,Witcher Dr,Brown-Augsburger PL,Wrooblewski VJ,Chlewicki LK。,Validation of a de-immunization strategy for monoclonal antibodies using cynomolgus macaque as a surrogate for human, Biopharm Drug Dispos. 2020 Mar;41(3):111-125. doi: 10.1002/bdd.2222. Epub 2020 Mar 10.
    瓦格伦,珍妮L;Carfagna,标记a;Koger,Deanna;斯科罗,马里奥;Kallman,Mary Jeanne;,在Cynomolgus MAKQUES中次级口服氯胺酮施用后的戒断评估。, Drug development research Vol.75, 2014

    Toxicology

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