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    老化

    Bolles, M., Deming, D., Long, K., Agnihothram, S., Whitmore, A., Ferris, M., . . . Baric, R. S. (2011).,双重失活的严重急性呼吸综合征冠状病毒疫苗在小鼠中提供不完全保护,并在挑战时诱导嗜酸性嗜酸性促血液炎症肺反应增加, Journal of Virology, 85(23), 12201-12215. doi:10.1128/JVI.06048-11 [doi]
    Corsetti,G.,Pasini,E.,Romano,C.,Calvani,R.,Picca,A.,Marzetti,E.。。。Dioguardi,F. S.(2018)。,Body weight loss and tissue wasting in late middle-aged mice on slightly imbalanced Essential/Non-essential amino acids diet.,5,136. Doi:10.3389 / Fmed.2018.00136 [Doi]中的医学前沿。
    罗克克斯,B.,巴亚斯,T.,佐尔尼泽,G。A、 ,哈格曼,B,谢汉,T,弗里曼,M。凯泽,M。G(2009年,急性呼吸窘迫综合征相关细胞因子的早期上调促进了严重急性呼吸综合征冠状病毒感染年龄 - 小鼠模型中的致死病,病毒学杂志,83(14),7062-7074。DOI:10.1128 / JVI.00127-09 [DOI]
    Barone, R., Macaluso, F., Catanese, P., Marino Gammazza, A., Rizzuto, L., Marozzi, P., . . . Di Felice, V. (2013).,耐力运动和共轭亚油酸(CLA)补充上调CYP17A1并刺激睾酮生物合成,Plos一个,8(11),E79686。DOI:10.1371 / journal.pone.0079686 [DOI]
    Clayton,E. H.,Garbow,J. R.,兼译团,P.V。(2011)。,磁共振弹性成像估计小鼠脑组织频率相关粘弹性参数,医学与生物学物理学,56(8),2391-2406。doi:10.1088/0031-9155/56/8/005 [内政部]
    Cayatte,C.,Snell Bennett,A.,Rajani,G. M.,Hostetler,L.,Maynard,S. K.,Lazzaro,M.,。。。Schneider-Ohrum,K。(2017)。,呼吸合胞病毒融合蛋白的次基疫苗候选较差和疗效与幼小小鼠的较差免疫原性和疗效。,Plos一,12(11),E0188708。DOI:10.1371 / journal.pone.0188708 [DOI]
    Grizenkova,J.,Akhtar,S.,Brandner,S.,Collance,J.,&Lloyd,S. E.(2014),Microglial Cx3cr1 knockout reduces prion disease incubation time in mice.BMC神经科学,15,44-2202-15-44。doi:10.1186/1471-2202-15-44 [内政部]

    抗体产生

    Rijal P, Wang BB, Tan TK, Schimanski L, Janesch P, Dong T, McCauley JW, Daniels RS, Townsend AR, Huang KA.,Broadly Inhibiting Antineuraminidase Monoclonal Antibodies Induced by Trivalent Influenza Vaccine and H7N9 Infection in Humans,j病毒。2020 Jan 31;94(4):e01182-19. doi: 10.1128/JVI.01182-19. Print 2020 Jan 31.
    McKitrick TR,Goth CK,Rosenberg CS,Nakahara H,Heimburg-Molinaro J,McQuillan Am,Falco R,Rivers NJ,Herrin Br,Cooper MD,Cummings Rd。,使用免疫射击液体的智能抗聚糖试剂的研制,公共生物。2020 Feb 28;3(1):91. doi: 10.1038/s42003-020-0819-2.
    Boyoglu-Barnum S, Hutchinson GB, Boyington JC, Moin SM, Gillespie RA, Tsybovsky Y, Stephens T, Vaile JR, Lederhofer J, Corbett KS, Fisher BE, Yassine HM, Andrews SF, Crank MC, McDermott AB, Mascola JR, Graham BS, Kanekiyo M.,Glycan repositioning of influenza hemagglutinin stem facilitates the elicitation of protective cross-group antibody responses,Nat Communce。2020 2月7日; 11(1):791。DOI:10.1038 / S41467-020-14579-4。

    Cardiovascular

    布鲁斯,A.C.,&Peirce,S. M.(2012)。,Exogenous thrombin delivery promotes collateral capillary arterialization and tissue reperfusion in the murine spinotrapezius muscle ischemia model.,微循环(纽约,N.Y.:1994),19(2),143-154。DOI:10.1111 / J.1549-8719.2011.00138.X [DOI]
    Schiviz, A., Magirr, D., Leidenmuhler, P., Schuster, M., Muchitsch, E. M., Hollriegl, W., & Subcommittee on Animal Models. (2014).,遗传背景对尾尖出血模型中出血表型的影响及标准化建议:距离SSC的沟通。《血栓与止血杂志》:JTH,12(11),1940-1942。doi:10.1111/jth.12700 [内政部]
    Kolosowska N, Gotkiewicz M, Dhungana H, Giudice L, Giugno R, Box D, Huuskonen MT, Korhonen P, Scoyni F, Kanninen KM, Ylä-Herttuala S, Turunen TA, Turunen MP, Koistinaho J, Malm T.,miR-669c的脑过度表达通过靶向MyD88并诱导替代的小胶质组/巨噬细胞激活来保护小鼠缺血性卒中模型, J Neuroinflammation. 2020 Jun 19;17(1):194. doi: 10.1186/s12974-020-01870-w.
    Stohr,R.,Mavilio,M.,Marino,A.,Casagrande,V.,Kappel,B.,Mollmann,J.。。。Federici,M。(2015),瘙痒调节SIRT6和SREBP2,以影响Apoe零小鼠中的脂质代谢和动脉粥样硬化。,科学报告,5,9023.Doi:10.1038 / srep09023 [Doi]
    De Hoog,V.C.,Timmers,L.,Van duijvenvoorde,A.,De Jager,S. C.,Van Middelaar,B. J.,Smeets,M. B.,。。。De Kleijn,D. P.(2014),Leucocyte expression of complement C5a receptors exacerbates infarct size after myocardial reperfusion injury心血管研究,103(4),521 - 529。doi: 10。1093/cvr/cvu153 [doi]
    Turner, J. K., McAllister, M. M., Xu, J. L., & Tapping, R. I. (2008).,The resistance of BALB/cJ mice to yersinia pestis maps to the major histocompatibility complex of chromosome 17., Infection and Immunity, 76(9), 4092-4099. doi:10.1128/IAI.00488-08 [doi]
    Antonioni A,Dimauro I,Fantini C,Barone R,Macaluso F,Di Felice V,Caporossi D.,αB结晶对小鼠心脏细胞中促氧化非细胞毒性环境的反应:“体外”和“体内”研究,自由基生物。2020年5月20日;152:301-312.doi:10.1016/j.freeradbomed.2020.03.013。Epub 2020年3月26日。

    新冠肺炎

    Tan T K, Rijal P, Rahikainen R, Keeble A H, Schimanski L, Hussain S, Harvey R, et al.,A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses,Biorxiv 2020.08.31.275701;DOI:https://doi.org/10.1101/2020.08.31.275701
    Dinnon Kh第3,Leist SR,SchäferA,爱德华州Ce,Martinez Dr,Montgomery Sa,West A,Yount Bl Jr,Hou Yj,Adams Le,Gully Kl,Brown Aj,Huang E,Bryant Md,Choong Ic,Glenn JS,格罗斯基·勒,切山TP,律师卢比。A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures, 自然。2020年10月; 586(7830):560-566。DOI:10.1038 / S41586-020-2708-8。EPUB 2020 8月27日。
    Leist SR, Dinnon KH 3rd, Schäfer A, Tse LV, Okuda K, Hou YJ, West A, Edwards CE, Sanders W, Fritch EJ, Gully KL, Scobey T, Brown AJ, Sheahan TP, Moorman NJ, Boucher RC, Gralinski LE, Montgomery SA, Baric RS.,A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice, 细胞。2020 Nov 12;183(4):1070-1085.e12. doi: 10.1016/j.cell.2020.09.050. Epub 2020 Sep 23.
    Schäfera,muecksch f,Lorenzi Jcc,Leist SR,Cipha M,Bournazos S,Schmidt F,Maison Rm,Gazumyan A,Martinez Dr,律师Rs,Robbiani DF,Hatziioannou T,Ravetch JV,Bieniasz PD,Bowen Ra,NussenzWeig MC,切汉TP。,体内SARS-COV-2感染保护和治疗的抗体效力,效应功能和组合,J Exp Med。2021年3月1日;218(3):E202011993。doi:10.1084/jem.20201993。
    van Doremalen N, Lambe T, Spencer A, Belij-Rammerstorfer S, Purushotham JN, Port JR, Avanzato V, Bushmaker T, Flaxman A, Ulaszewska M, Feldmann F, Allen ER, Sharpe H, Schulz J, Holbrook M, Okumura A, Meade-White K, Pérez-Pérez L, Bissett C, Gilbride C, Williamson BN, Rosenke R, Long D, Ishwarbhai A, Kailath R, Rose L, Morris S, Powers C, Lovaglio J, Hanley PW, Scott D, Saturday G, de Wit E, Gilbert SC, Munster VJ.,Chadox1 Ncov-19疫苗接种可防止在恒河猴中的SARS-COV-2肺炎, bioRxiv. 2020 May 13:2020.05.13.093195. doi: 10.1101/2020.05.13.093195. Preprint.
    van Doremalen N, Lambe T, Spencer A, Belij-Rammerstorfer S, Purushotham JN, Port JR, Avanzato VA, Bushmaker T, Flaxman A, Ulaszewska M, Feldmann F, Allen ER, Sharpe H, Schulz J, Holbrook M, Okumura A, Meade-White K, Pérez-Pérez L, Edwards NJ, Wright D, Bissett C, Gilbride C, Williamson BN, Rosenke R, Long D, Ishwarbhai A, Kailath R, Rose L, Morris S, Powers C, Lovaglio J, Hanley PW, Scott D, Saturday G, de Wit E, Gilbert SC, Munster VJ.,Chadox1 Ncov-19疫苗可防止SARS-COV-2在恒河猕猴中的肺炎, 自然。2020年10月; 586(7830):578-582。DOI:10.1038 / s41586-020-2608-y。EPUB 2020 7月30日。
    Menachery VD, Gralinski LE, Mitchell HD, Dinnon KH 3rd, Leist SR, Yount BL Jr, McAnarney ET, Graham RL, Waters KM, Baric RS.,联合衰减为减毒活冠状病毒疫苗提供了策略,j病毒。2018年8月16日; 92(17):E00710-18。DOI:10.1128 / JVI.00710-18。印刷2018年9月1日。
    格雷厄姆SP,MCLEAN RK,Spencer AJ,Belij-Rammerstorfer S,Wright D,Ulaszewska M,Edwards Jc,Hayes JWP,Martini V,Thakur N,Conceicao C,Dietrich I,Shelton H,Waters R,Ludi A,Wilsden G,Ludi A,Wilsden G,Ludi A,Wilsden G,Browning C,Bialy D,Bhat S,Stevenson-Leggett P,Hollinghurst P,Gilebride C,Pulido D,Moffat K,Sharpe H,Allen E,Mioulet V,Chiu C,Newman J,Asfor As,Burman A,Crossley S,Huo J,Owens RJ,Carroll M,Hammond Ja,Tchilian E,Bailey D,Charleston B,Gilbert SC,Tuthill TJ,Lambe T.,Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19,NPJ疫苗。2020年7月27日; 5:69。DOI:10.1038 / S41541-020-00221-3。ecollection 2020。
    李W,Schäfera,kulkarni ss,liu x,martinez博士,陈c,sun z,leiss sr,德利奇a,张l,ura ml,berezuk a,chittori s,Leopold k,mannar d,srivastava ss,zhu x,彼得森欧共体,曾康,梅勒斯JW,Falzarano D,Subramaniam S,律师Rs,Dimitrov DS。,High Potency of a Bivalent Human V(H) Domain in SARS-CoV-2 Animal Models, 细胞。2020年10月15日; 183(2):429-441.E16。DOI:10.1016 / J.Cell.2020.09.007。EPUB 2020 SEP 4。
    李W,Schäfera,kulkarni ss,liu x,martinez博士,陈c,sun z,leiss sr,德利奇a,张l,ura ml,berezuk a,chittori s,Leopold k,mannar d,srivastava ss,zhu x,彼得森欧共体,曾康,梅勒斯JW,Falzarano D,Subramaniam S,律师Rs,Dimitrov DS。,High Potency of a Bivalent Human V(H) Domain in SARS-CoV-2 Animal Models, 细胞。2020年10月15日; 183(2):429-441.E16。DOI:10.1016 / J.Cell.2020.09.007。EPUB 2020 SEP 4。
    Lainš?ek D, Fink T, Forstneri?, et al.,基于不同类型的SARS-COV-2穗蛋白的不同类型的纳米形型RBD结构域对疫苗候选的免疫反应,bioRxiv 2020.08.28.244269;内政部:https://doi.org/10.1101/2020.08.28.244269
    Capone S, Raggioli A, Gentile M, et al.,Covid-19的新大猩猩腺病毒疫苗候选者的免疫原性,Biorxiv 2020.10.22.349951;DOI:https://doi.org/10.1101/2020.10.22.349951
    Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Nkolola JP, Schäfer A, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Martinez DR, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Shrihari S, Mueller BK, Meiler J, Chandrashekar A, Mercado NB, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, McCune BT, Keeler SP, Holtzman MJ, Barouch DH, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE Jr.,Potently neutralizing and protective human antibodies against SARS-CoV-2, 自然。2020 Aug;584(7821):443-449. doi: 10.1038/s41586-020-2548-6. Epub 2020 Jul 15.
    李W,陈C,德利奇A,马丁内斯博士,格拉林斯基·勒,孙Z,SchäferA,Kulkarni SS,刘X,leistSr,zhelev dv,zhang l,金yj,Peterson ec,Conard A,Mellors JW,Tseng CK,falzarano d,arric rs,dimitrov ds。,Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection, Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29832-29838. doi: 10.1073/pnas.2010197117. Epub 2020 Nov 2.

    一般性研究

    Kropp, K. A., Hsieh, W. Y., Isern, E., Forster, T., Krause, E., Brune, W., . . . Ghazal, P. (2015).,A temporal gate for viral enhancers to co-opt toll-like-receptor transcriptional activation pathways upon acute infection.,Plos病原体,11(4),E1004737。DOI:10.1371 / journal.ppat.1004737 [DOI]
    Barone, R., Rappa, F., Macaluso, F., Caruso Bavisotto, C., Sangiorgi, C., Di Paola, G., . . . Marino Gammazza, A. (2016),Alcoholic liver disease: A mouse model reveals protection by lactobacillus fermentum.临床和转化胃肠病,7,e138。doi:10.1038/ctg.2015.66 [内政部]
    Pérez, Patricia; Marín, María Q; Lázaro-Frías, Adrián; Sorzano, Carlos Óscar S; Di Pilato, Mauro; Gómez, Carmen E; Esteban, Mariano; García-Arriaza, Juan; O,An MVA Vector Expressing HIV-1 Envelope under the Control of a Potent Vaccinia Virus Promoter as a Promising Strategy in HIV/AIDS Vaccine Design,疫苗Vol.7,2019
    Rubio-Solsona,E.,Marti,S.,Vilchez,J.J.,Palau,F.,&Hoenicka,J.(2018)。,在肌菌预体和肌肉纤维亚型中发现ANKK1与糖酵解代谢,PloS One,13(5),e0197254。doi:10.1371/journal.pone.0197254 [内政部]
    桦树,加布里埃尔;斯奈德,切尔西;罗伯特约旦;Kobayashi,Tetsuya;迪克,瑞安;PUSCAU,VLAD;李,李;Ramirez,Ricardo;Willkom,Madeleine;莫里克,吉田; Delaney Iv, William E; Schmitz, Uli,Anti-HBV activity of retinoid drugs in vitro versus in vivo, Antiviral research Vol.169, 2019
    Jansen Van Vuren,P.,Tiemessen,C.T.,&Paweska,J.T.(2011)。,Anti-nucleocapsid protein immune responses counteract pathogenic effects of rift valley fever virus infection in mice., PloS One, 6(9), e25027. doi:10.1371/journal.pone.0025027 [doi]
    Heinla,I.,Ahlgren,J.,Vasar,E.,&Voikar,V.(2018),C57BL / 6N和BALB / C雌性小鼠在社会家居笼中的行为特征 - 复杂环境中混合壳体的影响。, Physiology & Behavior, 188, 32-41. doi:S0031-9384(18)30032-5 [pii]
    Calabrese, G., Giuffrida, R., Forte, S., Salvatorelli, L., Fabbi, C., Figallo, E., . . . Gulino, R. (2016).,Bone augmentation after ectopic implantation of a cell-free collagen-hydroxyapatite scaffold in the mouse., Scientific Reports, 6, 36399. doi:10.1038/srep36399 [doi]
    苏维海米赫基;Hankaniemi,Minna M;Sioofy-Khojine,Amir-Babak;Laitinen, Olli H; Hyöty, Heikki; Hytönen, Vesa P; Vesikari, Timo; Blazevic, Vesna,Combination of three virus-derived nanoparticles as a vaccine against enteric pathogens; enterovirus, norovirus and rotavirus.,疫苗Vol.37,2019
    Rancilio, N. J., Dahl, S., Athanasiadi, I., & Perez-Torres, C. J. (2017).,使用临床线性加速器和强度调制放射疗法设计,构造和体内可行性,用于使用临床线性加速器和强度调制放射治疗小鼠大脑辐射。, International Journal of Radiation Biology, 93(12), 1321-1326. doi:10.1080/09553002.2017.1387305 [doi]
    Haste, L., Hulland, K., Bolton, S., Yesilkaya, H., McKechnie, K., & Andrew, P. W. (2014).,较低气道的链球菌肺炎链球菌感染长期鼠模型的发展与鉴定。, Infection and Immunity, 82(8), 3289-3298. doi:10.1128/IAI.01623-14 [doi]
    Desroches-Castan, Agnès; Tillet, Emmanuelle; Ricard, Nicolas; Ouarné, Marie; Mallet, Christine; Feige, Jean-Jacques; Bailly, Sabine,BMP9缺失对129 / OLA和C57BL / 6小鼠中肝内皮细胞分化和肝纤维化的差异后果。,细胞第8卷,2019年
    Brickman,T. J.,Hanawa,T.,Anderson,M.T.,Suhadolc,R. J.,&Armstrong,K。(2008)。,百日咳博德特氏菌ir的微分表达式on transport system genes during infection.,分子微生物学,70(1),3-14。DOI:10.1111 / J.1365-2958.2008.06333.x [DOI]
    Azcarate, I. G., Marin-Garcia, P., Kamali, A. N., Perez-Benavente, S., Puyet, A., Diez, A., & Bautista, J. M. (2014).,在小鼠中疟原虫感染疟原虫疟疾后的外周血中可检测到疟疾结果相关的差异免疫应答。, PloS One, 9(1), e85664. doi:10.1371/journal.pone.0085664 [doi]
    Browne, C. A., O'Brien, F. E., Connor, T. J., Dinan, T. G., & Cryan, J. F. (2012).,两种小鼠菌株海马的差异脂多糖诱导的免疫改变:应力的影响。, Neuroscience, 225, 237-248. doi:10.1016/j.neuroscience.2012.08.031 [doi]
    Stock, M., Kirchner, B., Waibler, D., Cowley, D. E., Pfaffl, M. W., & Kuehn, R. (2012),磁刺激对体外培养神经细胞基因表达谱的影响。, Neuroscience Letters, 526(2), 122-127. doi:10.1016/j.neulet.2012.08.024 [doi]
    Christie, R. D., Marcus, E. C., Wagner, A. M., & Besselsen, D. G. (2010).,仓鼠Parvovirus的小鼠实验感染:鼠标剖视图的误差的证据3。,比较医学,60(2),123-129。
    Romero, A., Gomez, O., Terrado, J., & Mesonero, J. E. (2009).,Glut8在小鼠肠中的表达:识别替代拼接变种, Journal of Cellular Biochemistry, 106(6), 1068-1078. doi:10.1002/jcb.22090 [doi]
    Plöhn,Svenja;水管,马蒂亚斯;Schlüter,anke;Michel,Lars;Diaz-Cano,Salvador;Hendgen-Cotta,Ulrike B;Banga,Jasvinder Paul;Bechrakis,Nikolaos E;汉森,威伯克;Eckstein,Anja; Berchner-Pfannschmidt, Utta;,Fingolimod Improves the Outcome of Experimental Graves Disease and Associated Orbitopathy by Modulating the Autoimmune Response to the Thyroid-Stimulating Hormone Receptor, Thyroid : official journal of the American Thyroid Association Vol.29, 2019
    Hankaniemi,Minna M;石头,弗吉尼亚州;安德谢夫,塔尼;苏维海米赫基;Sioofy-Khojine,Amir-Babak;马杰斯,瓦普;Hyöty,Heikki;Blazevic,Vesna;Flodström-tullberg,Malin;Hytönen,Vesa P; Laitinen, Olli H;,Formalin treatment increases the stability and immunogenicity of coxsackievirus B1 VLP vaccine., Antiviral research Vol.171, 2019
    Levison, S. E., Fisher, P., Hankinson, J., Zeef, L., Eyre, S., Ollier, W. E., . . . Pennock, J. L. (2013).,Trichuris Muris诱导的结肠炎模型的遗传分析显示QTL重叠和用于建立结肠炎症的新型基因簇。。BMC基因组学,14,127-2164-14-127。DOI:10.1186 / 1471-2164-14-127 [DOI]
    Jonczyk, M. S., Simon, M., Kumar, S., Fernandes, V. E., Sylvius, N., Mallon, A. M., . . . Andrew, P. W. (2014),Genetic factors regulating lung vasculature and immune cell functions associate with resistance to pneumococcal infection,PloS One,9(3),e89831。doi:10.1371/journal.pone.0089831 [内政部]
    Masetti, G., Moshkelgosha, S., Kohling, H. L., Covelli, D., Banga, J. P., Berchner-Pfannschmidt, U., . . . INDIGO consortium. (2018).,在不同环境中建立的坟墓的实验小鼠模型中的肠道微生物可以调节疾病的临床介绍。, Microbiome, 6(1), 97-018-0478-4. doi:10.1186/s40168-018-0478-4 [doi]
    Fercoq,Frédéric;留下,Estelle;Frohberger,Stefan J;瓦里拉诺 - 莱姆塔特,土地利地区;HOERAUF,APIM;约翰·鲁西尼;Landmann,Frédéric;Hübner,Marc P;Carlin,Leo M;马丁,科拉里,IL-4 receptor dependent expansion of lung CD169+ macrophages in microfilaria-driven inflammation,Plos忽略了热带疾病Vol.13,2019
    de Heusch M, Steenwinckel V, Cochez PM, Louahed J, Warnier G, Lemaire MM, Renauld JC, Dumoutier L.,IL-9施加生物学功能对抗原经验丰富的鼠T细胞,并加剧了通过养老转移引起的结肠炎, Eur J Immunol. 2020 Jul;50(7):1034-1043. doi: 10.1002/eji.201948430. Epub 2020 Mar 18.
    Ruiz-Manzano, Rocío Alejandra; Hernández-Cervantes, Rosalía; Del Río-Araiza, Víctor Hugo; Palacios-Arreola, Margarita Isabel; Nava-Castro, Karen Elizabeth; Morales-Montor, Jorge,Immune response to chronic Toxocara canis infection in a mice model., Parasite immunology Vol.41, 2019
    Tamminen,Kirsi;玛丽亚麦尔姆;维斯卡里,蒂莫;Blazevic,Vesna;,祖先的免疫交叉反应性和最近的大流行性诺罗病毒GII.4变体。,病毒Vol.11,2019
    Korhonen, P., Kanninen, K. M., Lehtonen, S., Lemarchant, S., Puttonen, K. A., Oksanen, M., . . . Malm, T. (2015),Immunomodulation by interleukin-33 is protective in stroke through modulation of inflammation,脑,行为和免疫,DOI:S0889-1591(15)00166-x [PII]
    Calabrese, G., Gulino, R., Giuffrida, R., Forte, S., Figallo, E., Fabbi, C., . . . Parenti, R. (2017).,体内评价细胞无胶原基支架的生物相容性和软骨潜力。,生理的前沿,8,984.Doi:10.3389 / fphes.2017.00984 [DOI]
    Brickman, T. J., Suhadolc, R. J., & Armstrong, S. K. (2015).,博尔德氏菌儿茶酚胺受体基因调控和功能的种间变异。,感染和免疫,83(12),4639-4652。DOI:10.1128 / IAI.00787-15 [DOI]
    Spacova, I; Petrova, M I; Fremau, A; Pollaris, L; Vanoirbeek, J; Ceuppens, J L; Seys, S; Lebeer, S;,鼻内施用益生菌乳酸乳杆菌GG防止桦树花粉诱导的鼠模型中的过敏性哮喘。过敏, Allergy Vol.74, 2019
    Kraan, H., Soema, P., Amorij, J. P., & Kersten, G. (2017).,鼻内和舌下递送灭活脊髓灰质炎疫苗。, Vaccine, 35(20), 2647-2653. doi:S0264-410X(17)30442-5 [pii]
    Spacova I, Van Beeck W, Seys S, Devos F, Vanoirbeek J, Vanderleyden J, Ceuppens J, Petrova M, Lebeer S.,Lactobacillus rhamnosus probiotic prevents airway function deterioration and promotes gut microbiome resilience in a murine asthma model,肠道微生物。2020年11月1日; 11(6):1729-1744。DOI:10.1080 / 19490976.2020.1766345。EPUB 2020 6月10日。
    Kraus, P., Xing, X., Lim, S. L., Fun, M. E., Sivakamasundari, V., Yap, S. P., . . . Lufkin, T. (2012),Lufkin,T.(2012)。小鼠菌株特异性基因表达胚胎中的illumina微阵列表达剖析差异,BMC研究说明,5,232-0500-5-232。DOI:10.1186 / 1756-0500-5-232 [DOI]
    Vono, Maria; Eberhardt, Christiane Sigrid; Auderset, Floriane; Mastelic-Gavillet, Beatris; Lemeille, Sylvain; Christensen, Dennis; Andersen, Peter; Lambert, Paul-Henri; Siegrist, Claire-Anne;,母体抗体抑制新生儿和婴儿反应通过塑造生发中心内的早期B细胞曲目来疫苗接种, Cell reports Vol.28, 2019
    Samaniego,R.,Estecha,A.,Relloso,M.,Longo,N.,Escat,J.L.,Longo-Imedio,I.,。。。Sanchez-Mateos,P。(2013),在人黑色素瘤组织中招生,渗透和定位白细胞的间充质贡献。, The Journal of Investigative Dermatology, 133(9), 2255-2264. doi:10.1038/jid.2013.88 [doi]
    Matusiak, N., van Waarde, A., Rozeveld, D., van Oosterhout, A. J., Heijink, I. H., Castelli, R., . . . Elsinga, P. H. (2015).,MicroPET evaluation of a hydroxamate-based MMP inhibitor, [F]FB-ML5, in a mouse model of cigarette smoke-induced acute airway inflammation., Molecular Imaging and Biology : MIB : The Official Publication of the Academy of Molecular Imaging, doi:10.1007/s11307-015-0847-3 [doi]
    Molera,L.,Meade-White,K。,星期六,G.,Scott,D.,&Bloom,M. E.(2017)。,培养Powassan病毒感染在Peromyscus Leucopus,自然宿主。, PLoS Neglected Tropical Diseases, 11(1), e0005346. doi:10.1371/journal.pntd.0005346 [doi]
    Gouveia, K., & Hurst, J. L. (2017).,Optimising reliability of mouse performance in behavioural testing: The major role of non-aversive handling., Scientific Reports, 7, 44999. doi:10.1038/srep44999 [doi]
    Kolosowska,Natalia;Keuters,Meike H;Wojciechowski,Sara;Keksa-goldsteine,velta;Laine,Mika;麦芽,塔拉;Goldsteins,Gundars;Koistinaho,贾里;德文达,弘南,Peripheral Administration of IL-13 Induces Anti-inflammatory Microglial/Macrophage Responses and Provides Neuroprotection in Ischemic Stroke.,神经治疗方法:美国实验神经治疗股份有关会杂志Vol.37,2019
    Draijer, C., Boorsma, C. E., Reker-Smit, C., Post, E., Poelstra, K., & Melgert, B. N. (2016),PGE2-treated macrophages inhibit development of allergic lung inflammation in mice., Journal of Leukocyte Biology, 100(1), 95-102. doi:10.1189/jlb.3MAB1115-505R [doi]
    Santio, N. M., Eerola, S. K., Paatero, I., Yli-Kauhaluoma, J., Anizon, F., Moreau, P., . . . Koskinen, P. J. (2015),PIM激酶促进前列腺癌异种移植物的迁移和转移性生长, PloS One, 10(6), e0130340. doi:10.1371/journal.pone.0130340 [doi]
    Kirchner,J.,Hackbarth,H.,Stelzer,H. D. D.,&Tsai,P. P.(2012)。,Preferences of group-housed female mice regarding structure of softwood bedding.,实验动物,46(2),95-100。DOI:10.1258 / LA.2011.010173 [DOI]
    Grosso-Becerra,M. V.,Santos-Medellin,C.,Gonzalez-Valdez,A.,Mendez,J.L.,Delgado,G.,Morales-Espinosa,R.,。。。Soberon-Chavez,G.(2014),假单胞菌铜绿假单胞菌临床和环境分离株构成了一种高表型多样性的人口。,BMC基因组学,15,318-2164-15-318。DOI:10.1186 / 1471-2164-15-318 [DOI]
    Rolot, Marion; M Dougall, Annette; Javaux, Justine; Lallemand, François; Machiels, Bénédicte; Martinive, Philippe; Dewals, Benjamin G;,单核细胞的肝巨噬细胞的募集是独立于IL-4R ??但与血吸虫病中的常规巨噬细胞消融有关。, European journal of immunology Vol.49, 2019
    Hofmann, S., Hilbe, M., Fajardo, R. J., Hagenmuller, H., Nuss, K., Arras, M., . . . Meinel, L. (2013).,Remodeling of tissue-engineered bone structures in vivo.。欧洲药学医学与生物食品学杂志:官方arbeitsgemeinschaft fur Pharmazeutische verfahrenstechnik E.v,85(1),119-129。DOI:10.1016 / J.EJPB.2013.02.011 [DOI]
    Percie du Sert N, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Hurst V, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T, Würbel H.,Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0, PLoS Biol. 2020 Jul 14;18(7):e3000411. doi: 10.1371/journal.pbio.3000411. eCollection 2020 Jul.
    Wiz,A.,Mandillo,S.,D'Amato,F. R.,Giuliani,A.,&Riviello,M. C.(2015),在C57BL / 6J和BALB / C小鼠中对小鼠房屋的响应,使用和习惯。, Experimental Animals / Japanese Association for Laboratory Animal Science, 64(3), 281-293. doi:10.1538/expanim.14-0104 [doi]
    玛丽亚麦尔姆;Diessner,André;Tamminen,Kirsi;Liebscher,Markus;维斯卡里,蒂莫;Blazevic,Vesna;,Rotavirus vp6作为在尼累累的诺育尼亚人生成的二价诺病毒疫苗的佐剂。,Pharmaceutics Vol.11,2019年
    OhiaNwoko,O.,Haile,C。N、 ,&Kosten,T。答(2017).,Sex differences in the acute locomotor response to methamphetamine in BALB/c mice.《行为大脑研究》,327,94-97。doi:S0166-4328(16) 31259-1[pii]
    纳瓦卡斯特罗,凯伦伊丽莎白;Solleiro-Villavicencio,海伦娜;Río-araiza,Víctorhugo del;塞戈维亚 - 门多萨,玛丽安娜;Pérez-Torres,Armando;Morales-Montor,Jorge,Sex-associated protective effect of early bisphenol-A exposure during enteric infection with Trichinella spiralis in mice, PloS one Vol.14, 2019
    van den Berg, W. E., Lamballais, S., & Kushner, S. A. (2015).,老鼠中社会等级的性别特定机制。, Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 40(6), 1364-1372. doi:10.1038/npp.2014.319 [doi]
    Hogenkamp, A., Thijssen, S., van Vlies, N., & Garssen, J. (2015).,Supplementing pregnant mice with a specific mixture of nondigestible oligosaccharides reduces symptoms of allergic asthma in male offspring.,营养杂志,145(3),640-646。DOI:10.3945 / JN.114.197707 [DOI]
    克莱纳,G.,西西,F.,特里科,P。M、 ,Zacchigna,S.,Crovella,S.,&Marzuzzi,A(2013).,Systemic and neuronal inflammatory markers in a mouse model of mevalonate kinase deficiency: A strain-comparative study.,体内(雅典,希腊),27(6),715-722。DOI:27/6/715 [PII]
    Milani C, Farina F, Botto L, Massimino L, Lonati E, Donzelli E, Ballarini E, Crippa L, Marmiroli P, Bulbarelli A, Palestini P.,Systemic Exposure to Air Pollution Induces Oxidative Stress and Inflammation in Mouse Brain, Contributing to Neurodegeneration Onset,int j mol sci。2020年5月24日; 21(10):3699。DOI:10.3390 / IJMS21103699
    Neill,D. R.,Fernandes,V. E.,Wisby,L.,Haynes,A. R.,Ferreira,D. M.,Laher,A.,。。。安德鲁,P. W.(2012)。,T调节细胞控制小鼠中侵入性肺炎球菌的敏感性。,Plos病原体,8(4),E1002660。DOI:10.1371 / journal.ppat.1002660 [DOI]
    Kemper, K., Rodermond, H., Colak, S., Grandela, C., & Medema, J. P. (2012).,Targeting colorectal cancer stem cells with inducible caspase-9, Apoptosis : An International Journal on Programmed Cell Death, 17(5), 528-537. doi:10.1007/s10495-011-0692-z [doi]
    Gustems Isern, E, M, Messerle, M, Borst, E, Ghazal, P., & Angulo, A. (2011).,活化剂蛋白1在人巨细胞病毒主要直接 - 早期增强剂内的结合基序在功能上是冗余的,并且在急性感染期间以NF-{kappa} B源以合作方式作用。, Journal of Virology, 85(4), 1732-1746. doi:10.1128/JVI.01713-10 [doi]
    Neill, D. R., Saint, G. L., Bricio-Moreno, L., Fothergill, J. L., Southern, K. W., Winstanley, C., . . . Flanagan, B. F. (2014).,The B lymphocyte differentiation factor (BAFF) is expressed in the airways of children with CF and in lungs of mice infected with pseudomonas aeruginosa,plos一个,9(5),E95892。DOI:10.1371 / journal.pone.0095892 [DOI]
    Fernandes VE, Ercoli G, Bénard A, Brandl C, Fahnenstiel H, Müller-Winkler J, Weber GF, Denny P, Nitschke L, Andrew PW.,B细胞抑制受体CD22是脑膜炎肺炎链球菌感染的主要因素,PLoS病理。2020年4月23日;16(4):e1008464。doi:10.1371/journal.ppat.1008464。eCollection 2020年4月。
    Spencer, A. J., Longley, R. J., Gola, A., Ulaszewska, M., Lambe, T., & Hill, A. V. (2017).,The threshold of protection from liver-stage malaria relies on a fine balance between the number of infected hepatocytes and effector CD8(+) T cells present in the liver, Journal of Immunology (Baltimore, Md.: 1950), 198(5), 2006-2016. doi:10.4049/jimmunol.1601209 [doi]
    Wong,S. H.,Walker,J.A.,Jolin,H. E.,Drynan,L. F.,火腿,E.,Camelo,A.,。。。McKenzie,A. N.(2012)。,Transcription factor RORalpha is critical for nuocyte development.,自然免疫学,13(3),229-236。DOI:10.1038 / NI.2208 [DOI]
    Craig,M.,Sadik,A. Y.,Golubeva,Y。,Tidhar,A.,&Slauch,J. M.(2013),由于包络缺陷,沙门氏菌的双精氨酸易位系统(TAT)突变体衰减,而不是呼吸缺陷。, Molecular Microbiology, 89(5), 887-902. doi:10.1111/mmi.12318 [doi]
    Tsai,P.P.,Nagelschmidt,N.,Kirchner,J.,Stelzer,H. D.,&Hackbarth,H.(2012)。,Validation of an automatic system (DoubleCage) for detecting the location of animals during preference tests.,实验动物,46(1),81-84。DOI:10.1258 / LA.2011.011072 [DOI]
    Yu, I. T., Park, J. Y., Kim, S. H., Lee, J. S., Kim, Y. S., & Son, H. (2009),Valproic acid promotes neuronal differentiation by induction of proneural factors in association with H4 acetylation, Neuropharmacology, 56(2), 473-480. doi:10.1016/j.neuropharm.2008.09.019 [doi]

    Infectious disease

    Tan T K, Rijal P, Rahikainen R, Keeble A H, Schimanski L, Hussain S, Harvey R, et al.,A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses,Biorxiv 2020.08.31.275701;DOI:https://doi.org/10.1101/2020.08.31.275701
    Dinnon Kh第3,Leist SR,SchäferA,爱德华州Ce,Martinez Dr,Montgomery Sa,West A,Yount Bl Jr,Hou Yj,Adams Le,Gully Kl,Brown Aj,Huang E,Bryant Md,Choong Ic,Glenn JS,格罗斯基·勒,切山TP,律师卢比。A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures, 自然。2020年10月; 586(7830):560-566。DOI:10.1038 / S41586-020-2708-8。EPUB 2020 8月27日。
    Leist SR, Dinnon KH 3rd, Schäfer A, Tse LV, Okuda K, Hou YJ, West A, Edwards CE, Sanders W, Fritch EJ, Gully KL, Scobey T, Brown AJ, Sheahan TP, Moorman NJ, Boucher RC, Gralinski LE, Montgomery SA, Baric RS.,A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice, 细胞。2020 Nov 12;183(4):1070-1085.e12. doi: 10.1016/j.cell.2020.09.050. Epub 2020 Sep 23.
    Schäfera,muecksch f,Lorenzi Jcc,Leist SR,Cipha M,Bournazos S,Schmidt F,Maison Rm,Gazumyan A,Martinez Dr,律师Rs,Robbiani DF,Hatziioannou T,Ravetch JV,Bieniasz PD,Bowen Ra,NussenzWeig MC,切汉TP。,体内SARS-COV-2感染保护和治疗的抗体效力,效应功能和组合,J Exp Med。2021年3月1日;218(3):E202011993。doi:10.1084/jem.20201993。
    van Doremalen N, Lambe T, Spencer A, Belij-Rammerstorfer S, Purushotham JN, Port JR, Avanzato VA, Bushmaker T, Flaxman A, Ulaszewska M, Feldmann F, Allen ER, Sharpe H, Schulz J, Holbrook M, Okumura A, Meade-White K, Pérez-Pérez L, Edwards NJ, Wright D, Bissett C, Gilbride C, Williamson BN, Rosenke R, Long D, Ishwarbhai A, Kailath R, Rose L, Morris S, Powers C, Lovaglio J, Hanley PW, Scott D, Saturday G, de Wit E, Gilbert SC, Munster VJ.,Chadox1 Ncov-19疫苗可防止SARS-COV-2在恒河猕猴中的肺炎, 自然。2020年10月; 586(7830):578-582。DOI:10.1038 / s41586-020-2608-y。EPUB 2020 7月30日。
    Menachery VD, Gralinski LE, Mitchell HD, Dinnon KH 3rd, Leist SR, Yount BL Jr, McAnarney ET, Graham RL, Waters KM, Baric RS.,联合衰减为减毒活冠状病毒疫苗提供了策略,j病毒。2018年8月16日; 92(17):E00710-18。DOI:10.1128 / JVI.00710-18。印刷2018年9月1日。
    Peniche AG,Osorio Ey,Melby PC,Travi BL。,组胺H1受体拮抗剂偶氮物和FexofeNAine对皮肤Leishmania的功效疗效, PLoS Negl Trop Dis. 2020 Aug 10;14(8):e0008482. doi: 10.1371/journal.pntd.0008482. eCollection 2020 Aug.
    李W,Schäfera,kulkarni ss,liu x,martinez博士,陈c,sun z,leiss sr,德利奇a,张l,ura ml,berezuk a,chittori s,Leopold k,mannar d,srivastava ss,zhu x,彼得森欧共体,曾康,梅勒斯JW,Falzarano D,Subramaniam S,律师Rs,Dimitrov DS。,High Potency of a Bivalent Human V(H) Domain in SARS-CoV-2 Animal Models, 细胞。2020年10月15日; 183(2):429-441.E16。DOI:10.1016 / J.Cell.2020.09.007。EPUB 2020 SEP 4。
    Lainš?ek D, Fink T, Forstneri?, et al.,基于不同类型的SARS-COV-2穗蛋白的不同类型的纳米形型RBD结构域对疫苗候选的免疫反应,bioRxiv 2020.08.28.244269;内政部:https://doi.org/10.1101/2020.08.28.244269
    Capone S, Raggioli A, Gentile M, et al.,Covid-19的新大猩猩腺病毒疫苗候选者的免疫原性,Biorxiv 2020.10.22.349951;DOI:https://doi.org/10.1101/2020.10.22.349951
    Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Nkolola JP, Schäfer A, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Martinez DR, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Shrihari S, Mueller BK, Meiler J, Chandrashekar A, Mercado NB, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, McCune BT, Keeler SP, Holtzman MJ, Barouch DH, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE Jr.,Potently neutralizing and protective human antibodies against SARS-CoV-2, 自然。2020 Aug;584(7821):443-449. doi: 10.1038/s41586-020-2548-6. Epub 2020 Jul 15.
    李W,陈C,德利奇A,马丁内斯博士,格拉林斯基·勒,孙Z,SchäferA,Kulkarni SS,刘X,leistSr,zhelev dv,zhang l,金yj,Peterson ec,Conard A,Mellors JW,Tseng CK,falzarano d,arric rs,dimitrov ds。,Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection, Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29832-29838. doi: 10.1073/pnas.2010197117. Epub 2020 Nov 2.
    Peterson NC, Berlin AA.,Risk Assessment for Use of a Porcine Circovirus-Contaminated Reagent in a Barrier Maintained Rodent Colony, J Am Assoc Lab Anim Sci. 2020 Sep 1;59(5):575-579. doi: 10.30802/AALAS-JAALAS-20-000012. Epub 2020 Jun 30.
    Solana JC,RamírezL,Cook Ec,Hernández-garcíae,Sacristáns,Martínem,ManuelGonzálezv,reguera rm,balaña-fouce r,fresno m,Requena JM,Iborra S,Soto M.,利什曼原虫HSP70-II突变株皮下免疫可降低BALB/c小鼠内脏利什曼病的严重性,疫苗(巴塞尔)。2020 3月23日; 8(1):141。DOI:10.3390 /疫苗80141。

    单克隆抗体

    Coutant,F.,Sanchez David,R. Y.,Felix,T.,Boulay,A.,Calechurn,L.,Souque,P.,。。。Charneau,P。(2012)。,一个nonintegrative慢病毒疫苗基于矢量provides long-term sterile protection against malaria., PloS One, 7(11), e48644. doi:10.1371/journal.pone.0048644 [doi]
    Reggiani, F., Labanca, V., Mancuso, P., Rabascio, C., Talarico, G., Orecchioni, S., . . . Bertolini, F. (2017).,Adipose progenitor cell secretion of GM-CSF and MMP9 promotes a stromal and immunological microenvironment that supports breast cancer progression,癌症研究,77(18),5169-5182。DOI:10.1158 / 0008-5472.CAN-17-0914 [DOI]
    Borges,O.,Silva,M.,De Sousa,A.,Borchard,G.,Junginger,H. E.,&Cordeiro-Da-Silva,A.(2008)。,Alginate coated chitosan nanoparticles are an effective subcutaneous adjuvant for hepatitis B surface antigen., International Immunopharmacology, 8(13-14), 1773-1780. doi:10.1016/j.intimp.2008.08.013 [doi]
    Aranda,J.,Garrido,M. E.,Cortes,P.,Llagostera,M.,&Barbe,J.(2008)。,Analysis of the protective capacity of three streptococcus suis proteins induced under divalent-cation-limited conditions., Infection and Immunity, 76(4), 1590-1598. doi:10.1128/IAI.00987-07 [doi]
    罗伯茨,A.,拉米兰德,E。W、 ,Vogel,L.,Jackson,J。P、 ,围场,C。D、 ,Guardner,J。子带,K(2008).,用于SARS-COV感染的动物模型和疫苗。,病毒研究,133(1),20-32。DOI:S0168-1702(07)00113-X [PII]
    Dobbs, N. A., Zhou, X., Pulse, M., Hodge, L. M., Schoeb, T. R., & Simecka, J. W. (2014),抗原脉冲骨髓衍生和肺枝状细胞在鼠支原体肺炎的发病机制过程中促进肺部的Th2细胞应答和免疫病理学。,免疫学杂志(巴尔的摩,MD:1950),193(3),1353-1363。DOI:10.4049 / Jimmunol.1301772 [Doi]
    Di尼罗、R。齐勒尔称,F。,御马,F。,Crovella S。, Stebel, M., Bestagno, M., . . . Sblattero, D. (2007),Construction of miniantibodies for the in vivo study of human autoimmune diseases in animal models,BMC生物技术,7,46。doi:1472-6750-7-46 [pii]项目
    Aranda,J.,Cortes,P.,Garrido,M. E.,Fittipaldi,N.,Llagostera,M.,Gottschalk,M.,&Barbe,J.(2009)。,Feob Transporter对链球菌毒力的贡献。国际微生物学, The Official Journal of the Spanish Society for Microbiology, 12(2), 137-143. doi:im2306131 [pii]
    Kapur, R., Heitink-Polle, K. M., Porcelijn, L., Bentlage, A. E., Bruin, M. C., Visser, R., . . . Vidarsson, G. (2015).,C-reactive protein enhances IgG-mediated phagocyte responses and thrombocytopenia., Blood, 125(11), 1793-1802. doi:10.1182/blood-2014-05-579110 [doi]
    Hastey, C. J., Elsner, R. A., Barthold, S. W., & Baumgarth, N. (2012).,延迟和转移标志着B细胞对勃艮第鲍力士感染的反应发展。, Journal of Immunology (Baltimore, Md.: 1950), 188(11), 5612-5622. doi:10.4049/jimmunol.1103735 [doi]
    Pence, B. D., Hester, S. N., Donovan, S. M., & Woods, J. A. (2012),Dietary whole glucan particles do not affect antibody or cell-mediated immune responses to influenza virus vaccination in mice., Immunological Investigations, 41(3), 275-289. doi:10.3109/08820139.2011.628732 [doi]
    Erova, T. E., Rosenzweig, J. A., Sha, J., Suarez, G., Sierra, J. C., Kirtley, M. L., . . . Chopra, A. K. (2013).,鉴赏外膜蛋白抗原作为新一代重组瘟疫疫苗的候选者的保护潜力评价。,临床和疫苗免疫学:CVI,20(2),227-238。DOI:10.1128 / CVI.00597-12 [DOI]
    Veceric-Haler, Z., Erman, A., Cerar, A., Motaln, H., Kolosa, K., Lah Turnsek, T., . . . Perse, M. (2016).,提高脐带干细胞移植对抗静电细胞球蛋白预处理的小鼠顺铂诱导肾损伤的改善,干细胞国际,2016,3585362.Doi:10.1155 / 2016/3585362 [Doi]
    Cabrera, M., Pewe, L. L., Harty, J. T., & Frevert, U. (2013),In vivo CD8+ T cell dynamics in the liver of plasmodium yoelii immunized and infected mice, PloS One, 8(8), e70842. doi:10.1371/journal.pone.0070842 [doi]
    Aranda,J.,Teixido,L.,Fittipaldi,N.,Cortes,P.,Llagostera,M.,Gottschalk,M.,&Barbe,J.(2012)。,编码锌结合脂蛋白103的基因的失活损害了链球菌的感染性。,加拿大兽医研究杂志= Revue Canadienne de Recherche Veterinaire,76(1),72-76。
    De Witte,C.,Taminiau,B.,Flahou,B.,Hautekiet,V.,Daube,G.,Ducatelle,R.,&Haesbrouck,F。(2018),饲料琥珀霉素用药诱导抗炎作用,并防止椎管细胞损失,而不会影响小鼠胃中的肠道肠道殖民化。,兽医研究,49(1),35-018-0530-1。DOI:10.1186 / s13567-018-0530-1 [DOI]
    Terwisscha van Scheltinga, A. G., van Dam, G. M., Nagengast, W. B., Ntziachristos, V., Hollema, H., Herek, J. L., . . . de Vries, E. G. (2011).,术中近红外荧光肿瘤成像与血管内皮生长因子和人表皮生长因子受体2靶向抗体。,核医学杂志:官方出版物,核医学会,52(11),1778-1785。DOI:10.2967 / JNUMED.111.092833 [DOI]
    Mastelic Gavillet, B., Eberhardt, C. S., Auderset, F., Castellino, F., Seubert, A., Tregoning, J. S., . . . Siegrist, C. A. (2015),MF59 mediates its B cell adjuvanticity by promoting T follicular helper cells and thus germinal center responses in adult and early life., Journal of Immunology (Baltimore, Md.: 1950), 194(10), 4836-4845. doi:10.4049/jimmunol.1402071 [doi]
    Kemper, K., Prasetyanti, P. R., De Lau, W., Rodermond, H., Clevers, H., & Medema, J. P. (2012).,单克隆抗体against Lgr5 identify human colorectal cancer stem cells, Stem Cells (Dayton, Ohio), 30(11), 2378-2386. doi:10.1002/stem.1233 [doi]
    Bubeck Wardenburg,J.,Palazzolo-Ballance,A. M.,Otto,M.,Schneewind,O.,&Deleo,F. R.(2008)。,Panton-valentine leukocidin is not a virulence determinant in murine models of community-associated methicillin-resistant staphylococcus aureus disease.,传染病杂志,198(8),1166-1170。DOI:10.1086 / 592053 [DOI]
    Cray, C., Besselsen, D. G., Hart, J. L., Yoon, D., Rodriguez, M., Zaias, J., & Altman, N. H. (2010).,急性期蛋白和蛋白质电泳在实验和天然感染小鼠中监测急性炎症过程的定量,比较医学,60(4),263-271。
    Odeh, A. N., & Simecka, J. W. (2016).,Regulatory CD4+CD25+ T cells dampen inflammatory disease in murine mycoplasma pneumonia and promote IL-17 and IFN-gamma responses., PloS One, 11(5), e0155648. doi:10.1371/journal.pone.0155648 [doi]
    Jahagirar,R.,attwell,S.,Marusic,S.,Bendele,A.,Shenoy,N.,Mclure,K。G.,。。。Kulikowski,E。(2017)。,RVX-297, a BET bromodomain inhibitor, has therapeutic effects in preclinical models of acute inflammation and autoimmune disease., Molecular Pharmacology, 92(6), 694-706. doi:10.1124/mol.117.110379 [doi]
    Elhaik Goldman, S., Dotan, S., Talias, A., Lilo, A., Azriel, S., Malka, I., . . . Mizrachi Nebenzahl, Y. (2016).,蛋白疫苗候选菌株肺炎链球菌果糖-1,6-二磷酸醛缩酶(streptoccuseuccuseuccuseumonicus,果糖-1,6-二磷酸醛缩酶)诱导Th1/Th2/Th17型细胞因子反应。,国际分子医学杂志,37(4),1127-1138。DOI:10.3892 / IJMM.2016.2512 [DOI]
    Rockx, B., Corti, D., Donaldson, E., Sheahan, T., Stadler, K., Lanzavecchia, A., & Baric, R. (2008),有效交叉中和人单克隆抗体保护对抗致命性致命性和人畜共患急性呼吸综合征冠状病毒攻击的结构基础,病毒学杂志,82(7),3220-3235。DOI:10.1128 / JVI.02377-07 [DOI]
    Hernandez, J. L., Padilla, L., Dakhel, S., Coll, T., Hervas, R., Adan, J., . . . Messeguer, R. (2013).,Therapeutic targeting of tumor growth and angiogenesis with a novel anti-S100A4 monoclonal antibody.,Plos一个,8(9),E72480。DOI:10.1371 / journal.pone.0072480 [DOI]
    Kuck,L. R.,Byrne-Nash,R.,Gillis,J.,Bueter,K。,Couzens,L.K.,Eichelberger,M. C. C.,&Rowlen,K. L.(2018)。,VaxArray for hemagglutinin and neuraminidase potency testing of influenza vaccines.,疫苗,36(21),2937-2945。DOI:S0264-410x(18)30545-0 [PII]

    肿瘤学

    Karp NA, Wilson Z, Stalker E, Mooney L, Lazic SE, Zhang B, Hardaker E.,多批次设计,提供有效性的稳健估计并减少动物使用——一个同源肿瘤案例研究, Sci Rep. 2020 Apr 10;10(1):6178. doi: 10.1038/s41598-020-62509-7.
    Forte,B. L.,Slosky,L. M.,张,H.,Arnold,M.R.,Staatz,W. D.,Hay,M.,。。。Vanderah,T. W.(2016)。,血管紧张素 - (1-7)/ MAS受体作为癌症诱导的骨疼痛的抗闭合症剂。,疼痛,157(12),2709-2721。DOI:10.1097 / J.PAIN.0000000000000690 [DOI]
    Bonavita E, Bromley CP, Jonsson G, Pelly VS, Sahoo S, Walwyn-Brown K, Mensurado S, Moeini A, Flanagan E, Bell CR, Chiang SC, Chikkanna-Gowda CP, Rogers N, Silva-Santos B, Jaillon S, Mantovani A, Reis E Sousa C, Guerra N, Davis DM, Zelenay S.,拮抗性炎症表型规定肿瘤命运并对免疫检查点封闭的反应, Immunity. 2020 Dec 15;53(6):1215-1229.e8. doi: 10.1016/j.immuni.2020.10.020. Epub 2020 Nov 20.
    怒族ñez Rivera A,Fournier PGJ,Arelano DL,RodriguezHernandez AG,Vazquez Duhalt R,Cadena Nava路。,用于生物医学目的的Brome马赛克病毒样颗粒作为siRNA纳米载体,贝尔斯坦j纳米医院。2020 2月20日; 11:372-382。DOI:10.3762 / BJNANO.11.28。ecollection 2020。
    Arroyo-Crespo, Juan J; Armiñán, Ana; Charbonnier, David; Deladriere, Coralie; Palomino-Schätzlein, Martina; Lamas-Domingo, Rubén; Forteza, Jerónimo; Pineda-Lucena, Antonio; Vicent, María J,三重阴性乳腺癌临床前模型的表征提供了转移性进展的功能证据。, International journal of cancer Vol.145, 2019
    Teijeira Á, Garasa S, Gato M, Alfaro C, Migueliz I, Cirella A, de Andrea C, Ochoa MC, Otano I, Etxeberria I, Andueza MP, Nieto CP, Resano L, Azpilikueta A, Allegretti M, de Pizzol M, Ponz-Sarvisé M, Rouzaut A, Sanmamed MF, Schalper K, Carleton M, Mellado M, Rodriguez-Ruiz ME, Berraondo P, Perez-Gracia JL, Melero I.,CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity, Immunity. 2020 May 19;52(5):856-871.e8. doi: 10.1016/j.immuni.2020.03.001. Epub 2020 Apr 13.
    法尔沃P、OreChioni S、Hillje R、Ravane A、Mancuso P、Camisaschi C、Luzi L、Pelicci P、Bertolini F。,Cyclophosphamide and vinorelbine activate stem-like CD8+ T cells and improve anti-PD-1 efficacy in triple-negative breast cancer, Cancer Res. 2020 Dec 2:canres.1818.2020. doi: 10.1158/0008-5472.CAN-20-1818. Online ahead of print.
    Shamni, Ofer; Grievink, Hilbert; Itamar, Batel; Mishani, Eyal; Abourbeh, Galith;,EAGFR突变阳性NSCLC宠物成像的ERLOTINIB氟化类似物的研制, Molecular imaging and biology Vol.21, 2019
    Subs Fv,邱Sq,yim Jj,Schrödercp,Timmer-Bosscha H,Bensen Es,Santini JT JR,De Vries Ege,Bogyo M,Van Dam Gm。,Fluorescent image-guided surgery in breast cancer by intravenous application of a quenched fluorescence activity-based probe for cysteine cathepsins in a syngeneic mouse model,ejnmmi res。2020年9月29日; 10(1):111。DOI:10.1186 / s13550-020-00688-0
    Rivera-Huerta, M., Lizarraga-Grimes, V. L., Castro-Torres, I. G., Tinoco-Mendez, M., Macias-Rosales, L., Sanchez-Bartez, F., . . . Gracia-Mora, M. I. (2017).,动物模型中益生元果实蛋白质癌的功能效应和动物模型中的钙代谢。, BioMed Research International, 2017, 9758982. doi:10.1155/2017/9758982 [doi]
    Sanchez-Gonzalez, B., Garcia-Vazquez, F. J., Farfan-Morales, J. E., & Jimenez-Zamudio, L. A. (2015).,Increased NHC cells in the peritoneal cavity of plasmacytoma susceptible BALB/c mouse.,炎症的介质,2015,313140. DOI:10.1155 / 2015/313140 [DOI]
    Kranjc Brezar S, Mrak V, Bosnjak M, Savarin M, Sersa G, Cemazar M.,Intratumoral Gene Electrotransfer of Plasmid DNA Encoding shRNA against Melanoma Cell Adhesion Molecule Radiosensitizes Tumors by Antivascular Effects and Activation of an Immune Response,疫苗(巴塞尔)。2020 Mar 19;8(1):135. doi: 10.3390/vaccines8010135.
    Alessandri,Giulio;Coccè,瓦伦蒂娜;牧师,法比奥;Paroni,丽塔;Dei Cas,米歇尔;弗朗切斯科·埃特雷利;Pollo,Bianca;Gatti,Laura;颤音,卡洛;Berenzi,angiola; Parati, Eugenio; Brini, Anna Teresa; Bondiolotti, Gianpietro; Ponzoni, Mirco; Pessina, Augusto,微碎片的人脂肪组织是一种用于药物递送的天然支架:癌症化疗的潜在应用。, Journal of controlled release : official journal of the Controlled Release Society Vol.302, 2019
    Bach-Griera M,Campo-PérezV,Barbosa S,Traserra S,Guallar-Garrido S,Moya-Andrico L,Herrero-AbadíaP,Luquin M,Rabanal RM,Torrent E,JuliánE.,Mycolicibacterium brumae Is a Safe and Non-Toxic Immunomodulatory Agent for Cancer Treatment,疫苗(巴塞尔)。2020 Apr 25;8(2):198. doi: 10.3390/vaccines8020198.
    Raineri D,Dianzani C,Cappellano G,Maione F,Baldanzi G,Iacobucci I,Clemente N,Baldone G,Boggio E,Gigliotti Cl,Boldorini R,Rojo JM,Monti M,Birolo L,Dianzani U,Chiocchetti A.,Osteopontin binds ICOSL promoting tumor metastasis,公共生物。2020年10月26日; 3(1):615。DOI:10.1038 / S42003-020-01333-1。
    Di Tano M,Raucci F,Vernieri C,Caffa I,Buono R,Fanti M,Brandhorst S,Curigliano G,Necioni A,De Brud F,Longo VD。,Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers,Nat Communce。2020年5月11日; 11(1):2332。DOI:10.1038 / S41467-020-16243-3。
    Pfitzer,丽莎;克里斯蒂娜•莫泽;Gegenfurtner,弗洛rian; Arner, Anja; Foerster, Florian; Atzberger, Carina; Zisis, Themistoklis; Kubisch-Dohmen, Rebekka; Busse, Johanna; Smith, Rebecca,Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy., Cell death & disease Vol.10, 2019
    Drescher F, Juárez P, Arellano DL, Serafín-Higuera N, Olvera-Rodriguez F, Jiménez S, Licea-Navarro AF, Fournier PG.,Tie2诱导乳腺癌细胞休眠,抑制骨转移的发展,癌症(巴塞尔)。2020年4月3日; 12(4):868。DOI:10.3390 / cance12040868。
    阮,o . N。格林,C,施耐德,l·S。曹,Y. K., Atzberger, C., Bartel, K., . . . Vollmar, A. M. (2017),Two-pore channel function is crucial for the migration of invasive cancer cells., Cancer Research, 77(6), 1427-1438. doi:10.1158/0008-5472.CAN-16-0852 [doi]
    Allen KL, Cann J, Zhao W, Peterson N, Lazzaro M, Zhong H, Wu H, Dall'Acqua WF, Borrok MJ, Damschroder MM, Tsui P, Li Q.,人非小细胞肺癌和啮齿动物肿瘤模型肿瘤内脉管系统中膜蛋白A1蛋白表达的上调, PLoS One. 2020 Jun 4;15(6):e0234268. doi: 10.1371/journal.pone.0234268. eCollection 2020.

    药理

    Narra,H.P.,Shubitz,L. F.,Mandel,M. A.,Trinh,H.T.,H.T.,Griffin,K。,Buntzman,A.,。。。orbach,m。j。(2016),A coccidioides posadasii CPS1 deletion mutant is avirulent and protects mice from lethal infection., Infection and Immunity, 84(10), 3007-3016. doi:10.1128/IAI.00633-16 [doi]
    Hirschberg, H., van Kuijk, S., Loch, J., Jiskoot, W., Bouwstra, J., Kersten, G., & Amorij, J. P. (2012).,A combined approach of vesicle formulations and microneedle arrays for transcutaneous immunization against hepatitis B virus.,欧洲医药科学杂志:欧洲医药科学联合会官方杂志,46(1-2),1-7。DOI:10.1016 / J.EJPS.2012.01.013 [DOI]
    Bolles, M., Deming, D., Long, K., Agnihothram, S., Whitmore, A., Ferris, M., . . . Baric, R. S. (2011).,双重失活的严重急性呼吸综合征冠状病毒疫苗在小鼠中提供不完全保护,并在挑战时诱导嗜酸性嗜酸性促血液炎症肺反应增加。, Journal of Virology, 85(23), 12201-12215. doi:10.1128/JVI.06048-11 [doi]
    Cestari,I.,Kalidas,S.,Monnerat,S.,Anupama,A.,Phillips,M. A.,&Stuart,K。(2013)。,一种多氨基酰基tRNA合成酶复合物,可增强非洲锥虫tRNA氨基酰化。,分子和细胞生物学,33(24),4872-4888。DOI:10.1128 / MCB.00711-13 [DOI]
    Sweeney,F.F.F.,O'Leary,O. F.,&Cryan,J. F.(2014)。,在早期的早期期间,活化而不是阻断Gabab受体会在Adulthood在Balb / C小鼠中改变焦虑。, Neuropharmacology, 81, 303-310. doi:10.1016/j.neuropharm.2013.08.039 [doi]
    Ferrini E, Mecozzi L, Corsi L, Ragionieri L, Donofrio G, Stellari FF.,阿尔法松和德Xmedetomidine作为气体麻醉用于博来霉素诱导的肺纤维化鼠模型的微型CT肺成像的替代品, Front Vet Sci. 2020 Oct 8;7:588592. doi: 10.3389/fvets.2020.588592. eCollection 2020.
    Movellan, J., Urban, P., Moles, E., de la Fuente, J. M., Sierra, T., Serrano, J. L., & Fernandez-Busquets, X. (2014).,Amphiphilic树突衍生物作为纳米载体的靶向促进抗疟药剂。, Biomaterials, 35(27), 7940-7950. doi:10.1016/j.biomaterials.2014.05.061 [doi]
    Novoa, E. M., Camacho, N., Tor, A., Wilkinson, B., Moss, S., Marin-Garcia, P., . . . Ribas de Pouplana, L. (2014).,天然氨基酰基-TRNA合成酶抑制剂在体内清除疟疾的类似物。《美利坚合众国国家科学院学报》,111(51),E508-17。doi:10.1073/pnas.1405994111 [内政部]
    Savignac,H. M.,Kiely,B.,Dinan,T.G.,&Cryan,J.F。(2014)。,双歧杆菌对BALB / C小鼠的应力相关行为和生理学产生应变特异性效果。, Neurogastroenterology and Motility : The Official Journal of the European Gastrointestinal Motility Society, 26(11), 1615-1627. doi:10.1111/nmo.12427 [doi]
    Savignac, H. M., Tramullas, M., Kiely, B., Dinan, T. G., & Cryan, J. F. (2015).,Bifidobacteria modulate cognitive processes in an anxious mouse strain,行为脑研究,287,59-72。DOI:10.1016 / J.BBR.2015.02.044 [DOI]
    Schnaider L, Toprakcioglu Z, Ezra A, Liu X, Bychenko D, Levin A, Gazit E, Knowles TPJ.,Biocompatible Hybrid Organic/Inorganic Microhydrogels Promote Bacterial Adherence and Eradication in Vitro and in Vivo, Nano Lett. 2020 Mar 11;20(3):1590-1597. doi: 10.1021/acs.nanolett.9b04290. Epub 2020 Feb 17.
    Felice, D., O'Leary, O. F., Pizzo, R. C., & Cryan, J. F. (2012).,Blockade of the GABA(B) receptor increases neurogenesis in the ventral but not dorsal adult hippocampus: Relevance to antidepressant action., Neuropharmacology, 63(8), 1380-1388. doi:10.1016/j.neuropharm.2012.06.066 [doi]
    Roux,C. M.,Rolan,H.G.G.G.G.,Santos,R.L.,Beremand,P. D.,Thomas,T.L.,Adams,L.G。,&Tsolis,R. M.(2007),布鲁氏菌需要功能型IV型分泌系统,以引发小鼠的天生免疫应答。,细胞微生物学,9(7),1851-1869。DOI:CMI922 [PII]
    Zogaj, X., Chakraborty, S., Liu, J., Thanassi, D. G., & Klose, K. E. (2008).,标题吐兰法兰西菌亚种的特征。novicidaⅣ型菌毛,微生物学(英国阅读),154(Pt 7),2139-2150。doi:10.1099/mic.0.2008/018077-0 [内政部]
    Liu, Y., Muir, B. W., Waddington, L. J., Hinton, T. M., Moffat, B. A., Hao, X., . . . Hughes, T. C. (2015).,胶体稳定的磁性碳纳米管在小鼠肝肿瘤中提供MRI对比度。, Biomacromolecules, 16(3), 790-797. doi:10.1021/bm501706x [doi]
    Oh, D. H., Lee, I. Y., Choi, M., Kim, S. H., & Son, H. (2012).,Comparison of neurite outgrowth induced by erythropoietin (EPO) and carbamylated erythropoietin (CEPO) in hippocampal neural progenitor cells., The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology, 16(4), 281-285. doi:10.4196/kjpp.2012.16.4.281 [doi]
    PérezP,MarínMQ,Lázaro-FriíasA,SorzanoCós,GómezCE,Esteban M,García-Arriaza J.,疫苗A40R基因缺失提高HIV-1疫苗候选MVA-B的免疫原性,疫苗(巴塞尔)。2020 2月6; 8(1):70。DOI:10.3390 /疫苗8010070。
    van der veen el,Subs Fv,Cleeren F,博姆斯G,Elsinga Ph,Hospers Gap,Lub-de Hooge Mn,De Vries Ege,De Vries EFJ,Antunes If.,白细胞介素-2-衍生的放射性机构对小鼠T细胞宠物成像的开发和评价,J Nucl Med。2020 SEP; 61(9):1355-1360。DOI:10.2967 / JNUMED.119.238782。EPUB 2020 2月28日。
    Azcarate,I. G.,Marin-Garcia,P.,Perez-Benavente,S.,Diez,A.,Puyet,A.,&Bautista,J. M.(2015),早期和后期的致死和自我固化的啮齿动物疟疾的免疫反应。,免疫学,220(5),684-691。DOI:10.1016 / J.IMBIO.2014.11.010 [DOI]
    Bjorn,C.,Noppa,L.,Naslund Salomonsson,E.,Johansson,A. L.,Nilsson,E.,Mahlapuu,M.,&Hakansson,J.(2015)。,Efficacy and safety profile of the novel antimicrobial peptide PXL150 in a mouse model of infected burn wounds., International Journal of Antimicrobial Agents, 45(5), 519-524. doi:10.1016/j.ijantimicag.2014.12.015 [doi]
    Kamali, A. N., Marin-Garcia, P., Azcarate, I. G., Puyet, A., Diez, A., & Bautista, J. M. (2015).,基于疟原虫抗实验性免疫gens isolated by antibody affinity.《免疫学研究杂志》,2015,723946。doi:10.1155/2015/723946 [内政部]
    Sweeney,F.F.F.,O'Leary,O. F.,&Cryan,J.F。(2013)。,Gabab受体配体在Balb / c小鼠中没有修饰条件恐惧反应。, Behavioural Brain Research, 256, 151-156. doi:10.1016/j.bbr.2013.07.035 [doi]
    Delviks-Frankenberry, K., Paprotka, T., Cingoz, O., Wildt, S., Hu, W. S., Coffin, J. M., & Pathak, V. K. (2013).,Generation of multiple replication-competent retroviruses through recombination between PreXMRV-1 and PreXMRV-2., Journal of Virology, 87(21), 11525-11537. doi:10.1128/JVI.01787-13 [doi]
    Burket JA, Pickle JC, Rusk AM, Haynes BA, Sharp JA, Deutsch SI.,Glycine transporter type 1 (GlyT1) inhibition improves conspecific-provoked immobility in BALB/c mice: Analysis of corticosterone response and glucocorticoid gene expression in cortex and hippocampus, Prog Neuropsychopharmacol Biol Psychiatry. 2020 Apr 20;99:109869. doi: 10.1016/j.pnpbp.2020.109869. Epub 2020 Jan 18.
    O'Connor, R. M., Pusceddu, M. M., O'Leary, O. F., Savignac, H. M., Bravo, J. A., El Yacoubi, M., . . . Cryan, J. F. (2013).,海马组III MGLU受体mRNA水平在应激,抑郁和抗抑郁作用的特定小鼠模型中没有改变。, Pharmacology, Biochemistry, and Behavior, 103(3), 561-567. doi:10.1016/j.pbb.2012.09.017 [doi]
    Borges,O.,Cordeiro-da-Silva,A.,Tavares,J.,Santarem,N.,De Sousa,A.,Borchard,G.,&Junginger,H. E.(2008),Immune response by nasal delivery of hepatitis B surface antigen and codelivery of a CpG ODN in alginate coated chitosan nanoparticles., European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 405-416. doi:10.1016/j.ejpb.2008.01.019 [doi]
    Brickman, T. J., & Armstrong, S. K. (2007).,Impact of alcaligin siderophore utilization on in vivo growth of bordetella pertussis.,感染和免疫,75(11),5305-5312。DOI:IAI.00849-07 [PII]
    Salomons,A. R.,Arndt,S.,&Ohl,F。(2012)。,焦虑谱对BALB / C和129P2小鼠认知性能的影响。, Cognitive, Affective & Behavioral Neuroscience, 12(4), 794-803. doi:10.3758/s13415-012-0109-7 [doi]
    Terwisscha van Scheltinga,A.G。,Lub-de Hooge,M. N.,Hinner,M.J.,Verheijen,R. B.,Allersdorfer,A.,Hulsmeyer,M。。。。Olwill,S. A.(2014),体内可视化Met肿瘤表达和抗氨基生物分布与梅特特异性抗氨基酸89ZR-PRS-110 PET示踪剂。, Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 55(4), 665-671. doi:10.2967/jnumed.113.124941 [doi]
    Savignac, H. M., Finger, B. C., Pizzo, R. C., O'Leary, O. F., Dinan, T. G., & Cryan, J. F. (2011),增加对慢性社会失败压力在天然焦急的鼠标菌株中的敏感性增加。, Neuroscience, 192, 524-536. doi:10.1016/j.neuroscience.2011.04.054 [doi]
    Gomez-Gallego,C.,Contado,M. C.,ILO,T.,Jaakkola,U. M.,Bernal,M.J.,Periago,M.J.,。。。Frias,R.(2012)。,Infant formula supplemented with polyamines alters the intestinal microbiota in neonatal BALB/cOlaHsd mice., The Journal of Nutritional Biochemistry, 23(11), 1508-1513. doi:10.1016/j.jnutbio.2011.10.003 [doi]
    Cestari, I., & Stuart, K. (2013,Inhibition of isoleucyl-tRNA synthetase as a potential treatment for human african trypanosomiasis., The Journal of Biological Chemistry, 288(20), 14256-14263. doi:10.1074/jbc.M112.447441 [doi]
    艾兹卡拉,我。G、 MarinGarcia,P.,Camacho,N.,PerezBenavente,S.,Pu尚未,A.,Diez,A。鲍蒂斯塔,J。M(2013).,Insights into the preclinical treatment of blood-stage malaria by the antibiotic borrelidin., British Journal of Pharmacology, 169(3), 645-658. doi:10.1111/bph.12156 [doi]
    Marriott, H. M., Gascoyne, K. A., Gowda, R., Geary, I., Nicklin, M. J., Iannelli, F., . . . Dockrell, D. H. (2012).,Interleukin-1beta regulates CXCL8 release and influences disease outcome in response to streptococcus pneumoniae, defining intercellular cooperation between pulmonary epithelial cells and macrophages, Infection and Immunity, 80(3), 1140-1149. doi:10.1128/IAI.05697-11 [doi]
    Blockus S, Sake SM, Wetzke M, Grethe C, Graalmann T, Pils M, Le Goffic R, Galloux M, Prochnow H, Rox K, Hüttel S, Rupcic Z, Wiegmann B, Dijkman R, Rameix-Welti MA, Eléouët JF, Duprex WP, Thiel V, Hansen G, Brönstrup M, Haid S, Pietschmann T.,Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry,抗病毒res。2020年5月; 177:104774。DOI:10.1016 / J.ANTIVIRAL.202020.104774。EPUB 2020 3月18日。
    Oude Munnink,T.H.,De Vries,E.G.,Vedelaar,S. R.,Timmer-Bosscha,H.,Schroder,C.P.,Brouwers,A. H.,&Lub-de Hooge,M. N.(2012)。,Lapatinib和17AAG减少89zr-Trastuzumab-F(AB')2在Skbr3肿瘤异种移植物中的摄取。,分子药剂,9(11),2995-3002。DOI:10.1021 / mp3002182 [DOI]
    O'Leary,O. F.,Zandy,S.,Dinan,T. G.,&Cryan,J. F.(2013)。,锂增强脱脂在治疗抑郁症小鼠模型中的影响:海马细胞增殖的作用。, Neuroscience, 228, 36-46. doi:10.1016/j.neuroscience.2012.09.072 [doi]
    O'Leary,O. F.,O'Connor,R. M.,&Cryan,J.F。(2012),锂诱导对成年海马神经发生的效果沿着应力小鼠的背腹轴线进行地拓扑。, Neuropharmacology, 62(1), 247-255. doi:10.1016/j.neuropharm.2011.07.015 [doi]
    范德比尔特,A。R、 ,Terwisscha van Scheltinga,A。G、 Timmer Bosscha,H.,Schroder,C。P、 ,Pot,L.,Kosterink,J。G。雷纳,A。K(2012).,测量肿瘤VEGF-A水平,具有89 ZR-BEVACIZUMAB宠物作为早期生物标志物,用于卵巢癌异种移植模型中everolimus治疗的抗血管生成效果。,临床癌症研究:官方癌症研究协会官方杂志,18(22),6306-6314。DOI:10.1158 / 1078-0432.ccr-12-0406 [DOI]
    Gottfries, J., Melgar, S., & Michaelsson, E. (2012).,全球物业屏幕模拟小鼠实验性结肠炎的建模:一种炎症肠疾病评估药物作用的整体方法。, PloS One, 7(1), e30005. doi:10.1371/journal.pone.0030005 [doi]
    Bragonzi,A.(2010),穗纤维化病原体急性和慢性肺部感染的鼠模型, International Journal of Medical Microbiology : IJMM, 300(8), 584-593. doi:10.1016/j.ijmm.2010.08.012 [doi]
    Muchnik, L., Adawi, A., Ohayon, A., Dotan, S., Malka, I., Azriel, S., . . . Nebenzahl, Y. M. (2013).,NADH氧化酶作为肺炎链球菌肺炎链球菌的粘附素,并引发小鼠的保护性免疫应答。,Plos一个,8(4),E61128。DOI:10.1371 / journal.pone.0061128 [DOI]
    Halbroth BR, Sebastian S, Salman AM, Ulaszewska M, Gola A, Longley RJ, Janse CJ, Khan SM, Hill AVS, Spencer AJ.,Preclinical Development and Assessment of Viral Vectors Expressing a Fusion Antigen of Plasmodium falciparum LSA1 and LSAP2 for Efficacy against Liver-Stage Malaria,感染免疫。2020年1月22日;88(2):e00573-19.doi:10.1128/IAI.00573-19.打印2020年1月22日。
    Flores-Villasenor, H., Canizalez-Roman, A., Velazquez-Roman, J., Nazmi, K., Bolscher, J. G., & Leon-Sicairos, N. (2012).,Protective effects of lactoferrin chimera and bovine lactoferrin in a mouse model of enterohaemorrhagic escherichia coli O157:H7 infection., Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire, 90(3), 405-411. doi:10.1139/o11-089 [doi]
    Gomez-Gallego, C., Collado, M. C., Perez, G., Ilo, T., Jaakkola, U. M., Bernal, M. J., . . . Salminen, S. (2014).,Resembling breast milk: Influence of polyamine-supplemented formula on neonatal BALB/cOlaHsd mouse microbiota., The British Journal of Nutrition, 111(6), 1050-1058. doi:10.1017/S0007114513003565 [doi]
    Savignac, H. M., Dinan, T. G., & Cryan, J. F. (2011).,小鼠对早期生活应激的抗性:遗传背景和应激持续时间的影响。,行为神经科学的前沿,5,13. Doi:10.3389 / Fnbeh.2011.00013 [DOI]
    England RM, Moss JI, Gunnarsson A, Parker JS, Ashford MB.,Synthesis and Characterization of Dendrimer-Based Polysarcosine Star Polymers: Well-Defined, Versatile Platforms Designed for Drug-Delivery Applications,生物大分子。2020年8月10日;21(8):3332-3341.doi:10.1021/acs.biomic.0c00768。Epub 2020年7月28日。
    莫拉莱斯,P.,Vara,D.,GomezCanas,M.,Zuniga,M。C、 ,OleaAzar,C.,Goya,P。杰格洛维奇,N(2013).,合成大麻喹啉:制备,体外抗增殖效应和体内前列腺抗肿瘤活性。,欧洲医药化学杂志,70,111-119。DOI:10.1016 / J.EJMECH.2013.09.043 [DOI]
    Gonzalez, R., Ferrin, G., Aguilar-Melero, P., Ranchal, I., Linares, C. I., Bello, R. I., . . . Muntane, J. (2013).,用一氧化氮供体策略靶向肝癌。, Antioxidants & Redox Signaling, 18(5), 491-506. doi:10.1089/ars.2011.4476 [doi]
    Suurs FV, Lorenczewski G, Stienen S, Friedrich M, de Vries EGE, de Groot DJA, Lub-de Hooge MN.,The Biodistribution of a CD3 and EpCAM Bispecific T-Cell Engager Is Driven by the CD3 Arm,J Nucl Med。2020年11月;61(11):1594-1601.doi:10.2967/jnumed.120.241877。Epub 2020年4月13日。
    Aranda,J.,Garrido,M. E.,Fittipaldi,N.,Cortes,P.,Llagostera,M.,Gottschalk,M.,&Barbe,J.(2010)。,The cation-uptake regulators AdcR and fur are necessary for full virulence of streptococcus suis., Veterinary Microbiology, 144(1-2), 246-249. doi:10.1016/j.vetmic.2009.12.037 [doi]
    Huuskonen,M.T.,Tuo,Q.Z.,Loppi,S.,Dhungana,H.,Korhonen,P.,Mcinnes,L. E.,。。。Kanninen,K. M.(2017)。,通过调节炎性Milieu,铜BIS(硫代硫代噻吩)复合Cu(II)(ATSM)是对脑缺血的保护性。《神经治疗学:美国实验神经治疗学会杂志》,14(2),519-532。doi:10.1007/s13311-016-0504-9 [内政部]
    Savignac,H. M.,Hyland,N.P.,Dinan,T. G.,&Cryan,J.F。(2011),重复社会交互应激对应激敏感小鼠行为和生理参数的影响。《行为大脑研究》,216(2),576-584。doi:10.1016/j.bbr.2010.08.049 [内政部]
    巴拉多斯,A. M.,Yuan,H.,Van der Stok,J.,Le Quang,B.,Fernandes,H.,Chaterjea,A.,。。。De Boer,J.(2012)。,遗传因素对小鼠磷酸钙陶瓷骨诱导电位的影响。,生物材料,33(23),5696-5705。DOI:10.1016 / J.Biomaterials.2012.04.021 [DOI]
    Roper, J., O'Carroll, A. M., Young, W.,3rd, & Lolait, S. (2011).,The vasopressin Avpr1b receptor: Molecular and pharmacological studies, Stress (Amsterdam, Netherlands), 14(1), 98-115. doi:10.3109/10253890.2010.512376 [doi]
    Makdasi E, Amsili S, Aronin A, Prigozhina TB, Tzdaka K, Gozlan YM, Ben Gigi-Tamir L, Sagiv JY, Shkedy F, Shani N, Tykocinski ML, Dranitzki Elhalel M.,毒理学and Pharmacokinetic Studies in Mice and Nonhuman Primates of the Nontoxic, Efficient, Targeted Hexameric FasL: CTLA4-FasL, Mol Cancer Ther. 2020 Feb;19(2):513-524. doi: 10.1158/1535-7163.MCT-19-0558. Epub 2019 Dec 23.
    城市,P.,Valle-Delgado,J. J.,Mauro,N.,Marques,J.,Manfredi,A.,Rottmann,M.,。。。Fernandez-Busquets,X.(2014)。,Use of poly(amidoamine) drug conjugates for the delivery of antimalarials to plasmodium,中国控释杂志:第177,84-95号控释会官方刊。DOI:10.1016 / J.JCONREL.2013.12.032 [DOI]
    Terwisscha Van Scheltinga,A.G.,Berghuis,P.,Nienhuis,H. H.,Timmer-Bosscha,H.,Pot,L.,Gaykema,S. B.,。。。Schroder,C. P.(2014)。,Visualising dual downregulation of insulin-like growth factor receptor-1 and vascular endothelial growth factor-A by heat shock protein 90 inhibition effect in triple negative breast cancer.,欧洲癌症杂志(牛津,英国:1990),50(14),2508-2516。DOI:10.1016 / J.EJCA.2014.06.008 [DOI]
    刘,Y.,Hughes,T.C.,Muir,B.W.,Waddington,L.J.,Gengenbach,T. R.,Easton,C. D.,。。。邱,J.(2014)。,Water-dispersible magnetic carbon nanotubes as T2-weighted MRI contrast agents, Biomaterials, 35(1), 378-386. doi:10.1016/j.biomaterials.2013.09.079 [doi]

    Teratology

    克雷格,M.,&Slauch,J. M.(2009),吞噬超氧化物特异性损害了抑制或杀死沙门氏菌的绝经靶标。, PloS One, 4(3), e4975. doi:10.1371/journal.pone.0004975 [doi]
    Montalban-Soler, L., Alarcon-Martinez, L., Jimenez-Lopez, M., Salinas-Navarro, M., Galindo-Romero, C., Bezerra de Sa, F., . . . Villegas-Perez, M. P. (2012).,Retinal compensatory changes after light damage in albino mice., Molecular Vision, 18, 675-693.
    Kawedia, J. D., Janke, L., Funk, A. J., Ramsey, L. B., Liu, C., Jenkins, D., . . . Relling, M. V. (2012).,小鼠模型中存活和骨瘦如柴的特异性差异。,比较医学,62(6),466-471。
    Williams,L.K.,Csaki,L. S.,Cantor,R. M.,Reue,K.,&Lawson,G. W.(2012)。,Ulcerative dermatitis in C57BL/6 mice exhibits an oxidative stress response consistent with normal wound healing, Comparative Medicine, 62(3), 166-171.

    毒理学

    Kienhuis, A. S., Slob, W., Gremmer, E. R., Vermeulen, J. P., & Ezendam, J. (2015).,A dose-response modeling approach shows that effects from mixture exposure to the skin sensitizers isoeugenol and cinnamal are in line with dose addition and not with synergism, Toxicological Sciences : An Official Journal of the Society of Toxicology, 147(1), 68-74. doi:10.1093/toxsci/kfv109 [doi]
    Ezendam,J.,vermeulen,J.P.P.,De Klerk,A.,De Jong,W.H.,沃尔·莱戈伦,H.(2012)。,定量评估皮肤敏化剂在诱导期的效能的方法。, Toxicology, 299(1), 20-24. doi:10.1016/j.tox.2012.05.002 [doi]
    Kavanagh,H.,&Mahon,B. P.(2011)。,异基因间充质干细胞通过诱导小鼠调节性T细胞,预防过敏性气道炎症。,过敏,66(4),523-531。DOI:10.1111 / J.1398-9995.2010.02509.x [DOI]
    Liu, C., Janke, L. J., Kawedia, J. D., Ramsey, L. B., Cai, X., Mattano, L. A.,Jr, . . . Relling, M. V. (2016).,Asparaginase potentiates glucocorticoid-induced osteonecrosis in a mouse model., PloS One, 11(3), e0151433. doi:10.1371/journal.pone.0151433 [doi]
    Rosáriof,duarte,如果,pinto rjb,santos c,hoet phm,oliveira h.,Biodistribution and pulmonary metabolic effects of silver nanoparticles in mice following acute intratracheal instillations,环境科学污染res int。2021年1月; 28(2):2301-2314。DOI:10.1007 / S11356-020-10563-Z。EPUB 2020 SEP 3。
    Nygaard,U.C.,Vinje,N.E.,Samuelsen,M.,Andreassen,M.,Greseng,E.C.,Bolling,A. K.,。。。Bodin,J.(2015)。,Early life exposure to bisphenol A investigated in mouse models of airway allergy, food allergy and oral tolerance.,食品和化学毒理学:一个国际期刊发表于英国工业生物研究协会,83,17-25。DOI:10.1016 / J.FCT.2015.05.009 [DOI]
    Janecek, E., Beineke, A., Schnieder, T., & Strube, C. (2014).,Neurotoxocarosis: Marked preference of toxocara canis for the cerebrum and T. cati for the cerebellum in the paratenic model host mouse., Parasites & Vectors, 7, 194-3305-7-194. doi:10.1186/1756-3305-7-194 [doi]
    Aranda,J.,Garrido,M. E.,Fittipaldi,N.,Cortes,P.,Llagostera,M.,Gottschalk,M.,&Barbe,J.(2009)。,Protective capacities of cell surface-associated proteins of streptococcus suis mutants deficient in divalent cation-uptake regulators., Microbiology (Reading, England), 155(Pt 5), 1580-1587. doi:10.1099/mic.0.026278-0 [doi]
    Purcell,B. P.,Elser,J.A.,Mu,A.,Margulies,K。B.,&Burdick,J. A.(2012)。,SDF-1alpha趋化因子与可降解水凝胶透明质酸释放的协同作用,可将骨髓源性细胞定向心肌。,生物材料,33(31),7849-7857。DOI:10.1016 / J.Biomaterials.2012.07.005 [DOI]
    Veiga,J.P.,Cooper,P. A.,Pors,K.,Patterson,L.H.,Bibby,M. C.,&Shigyder,S。D.(2011),中空纤维测定法用于评价DNA损伤剂。,药理毒理学方法杂志,64(3),226-232。DOI:10.1016 / J.Vascn.2011.04.006 [DOI]