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    Aging

    棉铃,M.,德明,D.,Long,K.,Agnihothram,S.,Whitmore,A.,Ferris,M。,。。。律师,R. S.(2011)。,A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge, Journal of Virology, 85(23), 12201-12215. doi:10.1128/JVI.06048-11 [doi]
    Corsetti, G., Pasini, E., Romano, C., Calvani, R., Picca, A., Marzetti, E., . . . Dioguardi, F. S. (2018).,Body weight loss and tissue wasting in late middle-aged mice on slightly imbalanced Essential/Non-essential amino acids diet., Frontiers in Medicine, 5, 136. doi:10.3389/fmed.2018.00136 [doi]
    罗克克斯,B.,巴亚斯,T.,佐尔尼泽,G。A、 ,哈格曼,B,谢汉,T,弗里曼,M。凯泽,M。G(2009年,急性呼吸窘迫综合征相关细胞因子的早期上调促进了严重急性呼吸综合征冠状病毒感染年龄 - 小鼠模型中的致死病, Journal of Virology, 83(14), 7062-7074. doi:10.1128/JVI.00127-09 [doi]
    Barone,R.,Macaluso,F.,Catanese,P.,Marino Gammazza,A.,Rizzuto,L.,Marozzi,P.,。。。Di Felice,V.(2013)。,耐力运动和共轭亚油酸(CLA)补充上调CYP17A1并刺激睾酮生物合成,Plos一个,8(11),E79686。DOI:10.1371 / journal.pone.0079686 [DOI]
    Clayton,E. H.,Garbow,J. R.,兼译团,P.V。(2011)。,磁共振弹性成像估计小鼠脑组织频率相关粘弹性参数,医学与生物学物理学,56(8),2391-2406。doi:10.1088/0031-9155/56/8/005 [内政部]
    Cayatte,C.,Snell Bennett,A.,Rajani,G. M.,Hostetler,L.,Maynard,S. K.,Lazzaro,M.,。。。Schneider-Ohrum,K。(2017)。,低免疫原性和有效性的呼吸器y syncytial virus fusion protein-based subunit vaccine candidates in aged versus young mice.,Plos一,12(11),E0188708。DOI:10.1371 / journal.pone.0188708 [DOI]
    Grizenkova,J.,Akhtar,S.,Brandner,S.,Collance,J.,&Lloyd,S. E.(2014),Micro胶囊CX3Cr1敲除降低小鼠中的朊病毒疾病孵育时间。BMC神经科学,15,44-2202-15-44。doi:10.1186/1471-2202-15-44 [内政部]

    抗体产生

    Rijal P, Wang BB, Tan TK, Schimanski L, Janesch P, Dong T, McCauley JW, Daniels RS, Townsend AR, Huang KA.,Broadly Inhibiting Antineuraminidase Monoclonal Antibodies Induced by Trivalent Influenza Vaccine and H7N9 Infection in Humans,j病毒。2020 Jan 31;94(4):e01182-19. doi: 10.1128/JVI.01182-19. Print 2020 Jan 31.
    McKitrick TR,Goth CK,Rosenberg CS,Nakahara H,Heimburg-Molinaro J,McQuillan Am,Falco R,Rivers NJ,Herrin Br,Cooper MD,Cummings Rd。,使用免疫射击液体的智能抗聚糖试剂的研制,公共生物。2020 2月28日; 3(1):91。DOI:10.1038 / S42003-020-0819-2。
    Boyoglu-Barnum S, Hutchinson GB, Boyington JC, Moin SM, Gillespie RA, Tsybovsky Y, Stephens T, Vaile JR, Lederhofer J, Corbett KS, Fisher BE, Yassine HM, Andrews SF, Crank MC, McDermott AB, Mascola JR, Graham BS, Kanekiyo M.,流感血凝素茎的甘草重新定位有助于保护性交叉群抗体反应的诱导,Nat Communce。2020 2月7日; 11(1):791。DOI:10.1038 / S41467-020-14579-4。

    Cardiovascular

    布鲁斯,A.C.,&Peirce,S. M.(2012)。,外源性凝血酶递送促进鼠旋转肌缺血模型中的抵押毛细血管动脉化和组织再灌注。,微循环(纽约,N.Y.:1994),19(2),143-154。DOI:10.1111 / J.1549-8719.2011.00138.X [DOI]
    Schiviz,A.,Magir,D.,Leidenmuhler,P.,Schuster,M.,Manditsch,E. M.,Hollriegl,W.和小组委员会在动物模型上。(2014)。,遗传背景对尾尖出血模型中出血表型的影响及标准化建议:距离SSC的沟通。《血栓与止血杂志》:JTH,12(11),1940-1942。doi:10.1111/jth.12700 [内政部]
    Kolosowska N, Gotkiewicz M, Dhungana H, Giudice L, Giugno R, Box D, Huuskonen MT, Korhonen P, Scoyni F, Kanninen KM, Ylä-Herttuala S, Turunen TA, Turunen MP, Koistinaho J, Malm T.,miR-669c的脑过度表达通过靶向MyD88并诱导替代的小胶质组/巨噬细胞激活来保护小鼠缺血性卒中模型, J Neuroinflammation. 2020 Jun 19;17(1):194. doi: 10.1186/s12974-020-01870-w.
    Stohr,R.,Mavilio,M.,Marino,A.,Casagrande,V.,Kappel,B.,Mollmann,J.。。。Federici,M。(2015),瘙痒调节SIRT6和SREBP2,以影响Apoe零小鼠中的脂质代谢和动脉粥样硬化。,科学报告,5,9023.Doi:10.1038 / srep09023 [Doi]
    De Hoog, V. C., Timmers, L., Van Duijvenvoorde, A., De Jager, S. C., Van Middelaar, B. J., Smeets, M. B., . . . De Kleijn, D. P. (2014),合成C5a受体的白细胞表达加剧了心肌再灌注损伤后的梗塞大小,心血管研究,103(4),521-529。DOI:10.1093 / CVR / CVU153 [DOI]
    特纳,J.K,M.,M.M.,Xu,J.L,&Tapp,R. I.(2008)。,BALB / CJ小鼠对Yersinia Pestis的抗性映射到染色体17的主要组织相容络合物。,感染和免疫,76(9),4092-4099。DOI:10.1128 / IAI.00488-08 [DOI]
    Antonioni A,Dimauro I,Fantini C,Barone R,Macaluso F,Di Felice V,Caporossi D.,αB-crystallin response to a pro-oxidant non-cytotoxic environment in murine cardiac cells: An "in vitro" and "in vivo" study,自由基生物。2020年5月20日;152:301-312.doi:10.1016/j.freeradbomed.2020.03.013。Epub 2020年3月26日。

    新冠肺炎

    Tan T K, Rijal P, Rahikainen R, Keeble A H, Schimanski L, Hussain S, Harvey R, et al.,使用SARS-COV-2穗蛋白受体结合结构域的截止物多聚化的Covid-19疫苗候选者诱导有效的中和抗体应答,Biorxiv 2020.08.31.275701;DOI:https://doi.org/10.1101/2020.08.31.275701
    Dinnon Kh第3,Leist SR,SchäferA,爱德华州Ce,Martinez Dr,Montgomery Sa,West A,Yount Bl Jr,Hou Yj,Adams Le,Gully Kl,Brown Aj,Huang E,Bryant Md,Choong Ic,Glenn JS,格罗斯基·勒,切山TP,律师卢比。SARS-COV-2的鼠标适应模型,以测试Covid-19对策, 自然。2020 Oct;586(7830):560-566. doi: 10.1038/s41586-020-2708-8. Epub 2020 Aug 27.
    Leist SR, Dinnon KH 3rd, Schäfer A, Tse LV, Okuda K, Hou YJ, West A, Edwards CE, Sanders W, Fritch EJ, Gully KL, Scobey T, Brown AJ, Sheahan TP, Moorman NJ, Boucher RC, Gralinski LE, Montgomery SA, Baric RS.,A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice, 细胞。2020 Nov 12;183(4):1070-1085.e12. doi: 10.1016/j.cell.2020.09.050. Epub 2020 Sep 23.
    Schäfer A, Muecksch F, Lorenzi JCC, Leist SR, Cipolla M, Bournazos S, Schmidt F, Maison RM, Gazumyan A, Martinez DR, Baric RS, Robbiani DF, Hatziioannou T, Ravetch JV, Bieniasz PD, Bowen RA, Nussenzweig MC, Sheahan TP.,Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo,J Exp Med。2021年3月1日;218(3):E202011993。doi:10.1084/jem.20201993。
    van Doremalen N, Lambe T, Spencer A, Belij-Rammerstorfer S, Purushotham JN, Port JR, Avanzato V, Bushmaker T, Flaxman A, Ulaszewska M, Feldmann F, Allen ER, Sharpe H, Schulz J, Holbrook M, Okumura A, Meade-White K, Pérez-Pérez L, Bissett C, Gilbride C, Williamson BN, Rosenke R, Long D, Ishwarbhai A, Kailath R, Rose L, Morris S, Powers C, Lovaglio J, Hanley PW, Scott D, Saturday G, de Wit E, Gilbert SC, Munster VJ.,ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques,Biorxiv。2020年5月13日:2020.05.13.093195。DOI:10.1101 / 2020.05.13.093195。预印刷品。
    Van Doremalen N,Lambe T,Spencer A,Belij-Rammerstorfer S,Purushotham Jn,Port JR,Avanzato VA,Bushmaker T,Flaxman A,Ulaszewska M,Feldmann F,Allen ER,Sharpe H,Schulz J,Holbrook M,Okumura A.,Meade-White K,Pérez-PérezL,爱德华兹NJ,Wright D,Bissett C,Gilbride C,Williamson BN,Rosenke R,Long D,Ishwarbhai A,Kailath R,Rose L,Morris S,Powers C,Lovaglio J,Hanley PW,Scott D,星期六G,De Wit E,Gilbert Sc,Munster VJ。,Chadox1 Ncov-19疫苗可防止SARS-COV-2在恒河猕猴中的肺炎, 自然。2020年10月; 586(7830):578-582。DOI:10.1038 / s41586-020-2608-y。EPUB 2020 7月30日。
    Menachery VD,Gralinski Le,Mitchell HD,Dinnon Kh 3,Leist SR,Yount Bl Jr,Mcanarney et,Graham Rl,Waters Km,律师卢比。,联合衰减为减毒活冠状病毒疫苗提供了策略,j病毒。2018年8月16日; 92(17):E00710-18。DOI:10.1128 / JVI.00710-18。印刷2018年9月1日。
    格雷厄姆SP,MCLEAN RK,Spencer AJ,Belij-Rammerstorfer S,Wright D,Ulaszewska M,Edwards Jc,Hayes JWP,Martini V,Thakur N,Conceicao C,Dietrich I,Shelton H,Waters R,Ludi A,Wilsden G,Ludi A,Wilsden G,Ludi A,Wilsden G,Browning C,Bialy D,Bhat S,Stevenson-Leggett P,Hollinghurst P,Gilebride C,Pulido D,Moffat K,Sharpe H,Allen E,Mioulet V,Chiu C,Newman J,Asfor As,Burman A,Crossley S,Huo J,Owens RJ,Carroll M,Hammond Ja,Tchilian E,Bailey D,Charleston B,Gilbert SC,Tuthill TJ,Lambe T.,用复制缺陷的病毒方法评价初级促进疫苗接种的免疫原性矢量化Covid-19疫苗候选Chadox1 Ncov-19,NPJ疫苗。2020年7月27日; 5:69。DOI:10.1038 / S41541-020-00221-3。ecollection 2020。
    李W,Schäfera,kulkarni ss,liu x,martinez博士,陈c,sun z,leiss sr,德利奇a,张l,ura ml,berezuk a,chittori s,Leopold k,mannar d,srivastava ss,zhu x,彼得森欧共体,曾康,梅勒斯JW,Falzarano D,Subramaniam S,律师Rs,Dimitrov DS。,High Potency of a Bivalent Human V(H) Domain in SARS-CoV-2 Animal Models, 细胞。2020年10月15日; 183(2):429-441.E16。DOI:10.1016 / J.Cell.2020.09.007。EPUB 2020 SEP 4。
    李W,Schäfera,kulkarni ss,liu x,martinez博士,陈c,sun z,leiss sr,德利奇a,张l,ura ml,berezuk a,chittori s,Leopold k,mannar d,srivastava ss,zhu x,彼得森欧共体,曾康,梅勒斯JW,Falzarano D,Subramaniam S,律师Rs,Dimitrov DS。,High Potency of a Bivalent Human V(H) Domain in SARS-CoV-2 Animal Models, 细胞。2020年10月15日; 183(2):429-441.E16。DOI:10.1016 / J.Cell.2020.09.007。EPUB 2020 SEP 4。
    Lainš?ek D, Fink T, Forstneri?, et al.,基于不同类型的SARS-COV-2穗蛋白的不同类型的纳米形型RBD结构域对疫苗候选的免疫反应,bioRxiv 2020.08.28.244269;内政部:https://doi.org/10.1101/2020.08.28.244269
    Capone S,Raggioli A,Gentile M等人,Immunogenicity of a new gorilla adenovirus vaccine candidate for COVID-19, bioRxiv 2020.10.22.349951; doi: https://doi.org/10.1101/2020.10.22.349951
    Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Nkolola JP, Schäfer A, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Martinez DR, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Shrihari S, Mueller BK, Meiler J, Chandrashekar A, Mercado NB, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, McCune BT, Keeler SP, Holtzman MJ, Barouch DH, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE Jr.,Potently neutralizing and protective human antibodies against SARS-CoV-2, 自然。2020 Aug;584(7821):443-449. doi: 10.1038/s41586-020-2548-6. Epub 2020 Jul 15.
    李W,陈C,德利奇A,马丁内斯博士,格拉林斯基·勒,孙Z,SchäferA,Kulkarni SS,刘X,leistSr,zhelev dv,zhang l,金yj,Peterson ec,Conard A,Mellors JW,Tseng CK,falzarano d,arric rs,dimitrov ds。,Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection, Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29832-29838. doi: 10.1073/pnas.2010197117. Epub 2020 Nov 2.

    一般性研究

    Kropp, K. A., Hsieh, W. Y., Isern, E., Forster, T., Krause, E., Brune, W., . . . Ghazal, P. (2015).,A temporal gate for viral enhancers to co-opt toll-like-receptor transcriptional activation pathways upon acute infection., PLoS Pathogens, 11(4), e1004737. doi:10.1371/journal.ppat.1004737 [doi]
    Barone, R., Rappa, F., Macaluso, F., Caruso Bavisotto, C., Sangiorgi, C., Di Paola, G., . . . Marino Gammazza, A. (2016),酒精性肝病:小鼠模型揭示了乳酸杆菌的保护。临床和转化胃肠病,7,e138。doi:10.1038/ctg.2015.66 [内政部]
    Pérez,Patricia;Marín,玛丽亚Q;Lázaro-Friasas,Adrián;Sorzano,Carlosóscars;莫罗迪加拉托;Gómez,卡门e;Esteban,Mariano;García-Arriaza,Juan;哦,An MVA Vector Expressing HIV-1 Envelope under the Control of a Potent Vaccinia Virus Promoter as a Promising Strategy in HIV/AIDS Vaccine Design,疫苗Vol.7,2019
    Rubio-Solsona,E.,Marti,S.,Vilchez,J.J.,Palau,F.,&Hoenicka,J.(2018)。,ANKK1 is found in myogenic precursors and muscle fibers subtypes with glycolytic metabolism,PloS One,13(5),e0197254。doi:10.1371/journal.pone.0197254 [内政部]
    桦树,加布里埃尔;斯奈德,切尔西;罗伯特约旦;Kobayashi,Tetsuya;迪克,瑞安;PUSCAU,VLAD;李,李;Ramirez,Ricardo;Willkom,Madeleine;莫里克,吉田; Delaney Iv, William E; Schmitz, Uli,类视黄醇类药物在体外与体内的抗HBV活性,抗病毒研究Vol.169,2019
    Jansen Van Vuren,P.,Tiemessen,C.T.,&Paweska,J.T.(2011)。,Anti-nucleocapsid protein immune responses counteract pathogenic effects of rift valley fever virus infection in mice., PloS One, 6(9), e25027. doi:10.1371/journal.pone.0025027 [doi]
    Heinla, I., Ahlgren, J., Vasar, E., & Voikar, V. (2018),Behavioural characterization of C57BL/6N and BALB/c female mice in social home cage - effect of mixed housing in complex environment.,生理和行为,188,32-41。DOI:S0031-9384(18)30032-5 [PII]
    Calabrese,G.,Giuffrida,R.,Forte,S.,Salvatorelli,L.,Fabbi,C.,Figopto,E.。。。古利诺,R。(2016)。,Bone augmentation after ectopic implantation of a cell-free collagen-hydroxyapatite scaffold in the mouse., Scientific Reports, 6, 36399. doi:10.1038/srep36399 [doi]
    苏维海米赫基;Hankaniemi,Minna M;Sioofy-Khojine,Amir-Babak;丽贝,olli h;Hyöty,Heikki;Hytönen,Vesa P;维斯卡里,蒂莫;Blazevic,Vesna,三种病毒衍生的纳米颗粒作为针对肠溶病原体的疫苗的组合;肠道病毒,诺罗病毒和轮状病毒。, Vaccine Vol.37, 2019
    Rancilio, N. J., Dahl, S., Athanasiadi, I., & Perez-Torres, C. J. (2017).,使用临床线性加速器和强度调制放射疗法设计,构造和体内可行性,用于使用临床线性加速器和强度调制放射治疗小鼠大脑辐射。,国际辐射生物学杂志,93(12),1321-1326。DOI:10.1080 / 09553002.2017.1387305 [DOI]
    匆忙,L.,Hulland,K。,博尔顿,S.,Yesilkaya,H.,McKechnie,K。,Andrew,P. W.(2014)。,较低气道的链球菌肺炎链球菌感染长期鼠模型的发展与鉴定。,感染和免疫,82(8),3289-3298。DOI:10.1128 / IAI.01623-14 [DOI]
    Desroches-Castan, Agnès; Tillet, Emmanuelle; Ricard, Nicolas; Ouarné, Marie; Mallet, Christine; Feige, Jean-Jacques; Bailly, Sabine,Differential Consequences of Bmp9 Deletion on Sinusoidal Endothelial Cell Differentiation and Liver Fibrosis in 129/Ola and C57BL/6 Mice., Cells Vol.8, 2019
    Brickman,T. J.,Hanawa,T.,Anderson,M.T.,Suhadolc,R. J.,&Armstrong,K。(2008)。,百日咳博德特氏菌ir的微分表达式on transport system genes during infection.,分子微生物学,70(1),3-14。DOI:10.1111 / J.1365-2958.2008.06333.x [DOI]
    Azcarate,I. G.,Marin-Garcia,P.,Kamali,A. N.,Perez-Benavente,S.,Puyet,A.,Diez,A.,&Bautista,J. M.(2014)。,Differential immune response associated to malaria outcome is detectable in peripheral blood following plasmodium yoelii infection in mice., PloS One, 9(1), e85664. doi:10.1371/journal.pone.0085664 [doi]
    Browne,C. A.,O'Brien,F. E.,Connor,T. J.,Dinan,T. G.,J.F。(2012)。,两种小鼠菌株海马的差异脂多糖诱导的免疫改变:应力的影响。, Neuroscience, 225, 237-248. doi:10.1016/j.neuroscience.2012.08.031 [doi]
    Stock, M., Kirchner, B., Waibler, D., Cowley, D. E., Pfaffl, M. W., & Kuehn, R. (2012),磁刺激对体外培养神经细胞基因表达谱的影响。, Neuroscience Letters, 526(2), 122-127. doi:10.1016/j.neulet.2012.08.024 [doi]
    Christie, R. D., Marcus, E. C., Wagner, A. M., & Besselsen, D. G. (2010).,Experimental infection of mice with hamster parvovirus: Evidence for interspecies transmission of mouse parvovirus 3.,比较医学,60(2),123-129。
    Romero, A., Gomez, O., Terrado, J., & Mesonero, J. E. (2009).,Glut8在小鼠肠中的表达:识别替代拼接变种, Journal of Cellular Biochemistry, 106(6), 1068-1078. doi:10.1002/jcb.22090 [doi]
    Plöhn,Svenja;水管,马蒂亚斯;Schlüter,anke;Michel,Lars;Diaz-Cano,Salvador;Hendgen-Cotta,Ulrike B;Banga,Jasvinder Paul;Bechrakis,Nikolaos E;汉森,威伯克;Eckstein,Anja; Berchner-Pfannschmidt, Utta;,Fingolimod Improves the Outcome of Experimental Graves Disease and Associated Orbitopathy by Modulating the Autoimmune Response to the Thyroid-Stimulating Hormone Receptor,甲状腺:美国甲状腺协会官方杂志Vol.29,2019
    Hankaniemi,Minna M;Stone, Virginia M; Andrejeff, Tanja; Heinimäki, Suvi; Sioofy-Khojine, Amir-Babak; Marjomäki, Varpu; Hyöty, Heikki; Blazevic, Vesna; Flodström-Tullberg, Malin; Hytönen, Vesa P; Laitinen, Olli H;,Formalin treatment increases the stability and immunogenicity of coxsackievirus B1 VLP vaccine.,抗病毒研究Vol.171,2019
    Levison,S. E.,Fisher,P.,Hankinson,J.,Zeef,L.,Eyre,S。,Ollier,W. E.,。。。Pennock,J.L.(2013)。,Genetic analysis of the trichuris muris-induced model of colitis reveals QTL overlap and a novel gene cluster for establishing colonic inflammation.。BMC Genomics, 14, 127-2164-14-127. doi:10.1186/1471-2164-14-127 [doi]
    Jonczyk, M. S., Simon, M., Kumar, S., Fernandes, V. E., Sylvius, N., Mallon, A. M., . . . Andrew, P. W. (2014),Genetic factors regulating lung vasculature and immune cell functions associate with resistance to pneumococcal infection,PloS One,9(3),e89831。doi:10.1371/journal.pone.0089831 [内政部]
    Masetti, G., Moshkelgosha, S., Kohling, H. L., Covelli, D., Banga, J. P., Berchner-Pfannschmidt, U., . . . INDIGO consortium. (2018).,在不同环境中建立的坟墓的实验小鼠模型中的肠道微生物可以调节疾病的临床介绍。, Microbiome, 6(1), 97-018-0478-4. doi:10.1186/s40168-018-0478-4 [doi]
    Fercoq,Frédéric;留下,Estelle;Frohberger,Stefan J;瓦里拉诺 - 莱姆塔特,土地利地区;HOERAUF,APIM;约翰·鲁西尼;Landmann,Frédéric;Hübner,Marc P;Carlin,Leo M;马丁,科拉里,IL-4 receptor dependent expansion of lung CD169+ macrophages in microfilaria-driven inflammation, PLoS neglected tropical diseases Vol.13, 2019
    De Heusch M,Steenwinckel V,Cochez PM,Louahed J,Warnier G,Lemaire MM,Renauld JC,Dumoutier L.,IL-9施加生物学功能对抗原经验丰富的鼠T细胞,并加剧了通过养老转移引起的结肠炎, Eur J Immunol. 2020 Jul;50(7):1034-1043. doi: 10.1002/eji.201948430. Epub 2020 Mar 18.
    Ruiz-Manzano,RocíoAlejandra;Hernández-Cervantes,Rosalía;DelRío-Araza,Víctor雨果;Palacios-Arreola,Margarita Isabel;纳瓦卡斯特罗,凯伦伊丽莎白;Morales-Montor,Jorge,小鼠模型中对慢性毒素Canis感染的免疫应答。, Parasite immunology Vol.41, 2019
    Tamminen,Kirsi;玛丽亚麦尔姆;维斯卡里,蒂莫;Blazevic,Vesna;,祖先的免疫交叉反应性和最近的大流行性诺罗病毒GII.4变体。, Viruses Vol.11, 2019
    Korhonen, P., Kanninen, K. M., Lehtonen, S., Lemarchant, S., Puttonen, K. A., Oksanen, M., . . . Malm, T. (2015),白细胞介素-33的免疫调节是通过调节炎症的中风保护,脑,行为和免疫,DOI:S0889-1591(15)00166-x [PII]
    Calabrese,G.,Gulino,R.,Giuffrida,R.,Forte,S.,Figoplo,E.,Fabbi,C.,。。。Parenti,R。(2017)。,体内评价细胞无胶原基支架的生物相容性和软骨潜力。,生理的前沿,8,984.Doi:10.3389 / fphes.2017.00984 [DOI]
    Brickman, T. J., Suhadolc, R. J., & Armstrong, S. K. (2015).,博尔德氏菌儿茶酚胺受体基因调控和功能的种间变异。, Infection and Immunity, 83(12), 4639-4652. doi:10.1128/IAI.00787-15 [doi]
    Spacova, I; Petrova, M I; Fremau, A; Pollaris, L; Vanoirbeek, J; Ceuppens, J L; Seys, S; Lebeer, S;,Intranasal administration of probiotic Lactobacillus rhamnosus GG prevents birch pollen-induced allergic asthma in a murine model. Allergy,过敏Vol.74,2019
    Kraan, H., Soema, P., Amorij, J. P., & Kersten, G. (2017).,Intranasal and sublingual delivery of inactivated polio vaccine.,疫苗,35(20),2647-2653。DOI:S0264-410x(17)30442-5 [PII]
    Spacova I,Van Beeck W,Seys S,Devos F,Vanoirobeek J,Vanderleyden J,Ceuppens J,Petrova M,Lebeer S.,Lactobacillus rhamnosus probiotic prevents airway function deterioration and promotes gut microbiome resilience in a murine asthma model,肠道微生物。2020年11月1日; 11(6):1729-1744。DOI:10.1080 / 19490976.2020.1766345。EPUB 2020 6月10日。
    Kraus,P.,Xing,X.,Lim,S.L.,Fun,M. E.,Sivakamasundari,V.,Yap,S. P.,。。。Lufkin,T.(2012),Lufkin, T. (2012). Mouse strain specific gene expression differences for illumina microarray expression profiling in embryos, BMC Research Notes, 5, 232-0500-5-232. doi:10.1186/1756-0500-5-232 [doi]
    玛利亚瓦乔;Eberhardt,Christiane Sigrid;奥斯特,Floriane;Mastelic-Gavillet,Beatris;Lemeille,Sylvain;克里斯滕森,丹尼斯;安德森,彼得;Lambert,Paul-Henri;Siegrist,Claire-Anne;母体抗体抑制新生儿和婴儿反应通过塑造生发中心内的早期B细胞曲目来疫苗接种,细胞报告Vol.28,2019年
    Samaniego,R.,Estecha,A.,Relloso,M.,Longo,N.,Escat,J.L.,Longo-Imedio,I.,。。。Sanchez-Mateos,P。(2013),在人黑色素瘤组织中招生,渗透和定位白细胞的间充质贡献。, The Journal of Investigative Dermatology, 133(9), 2255-2264. doi:10.1038/jid.2013.88 [doi]
    Matusiak,N.,Van Waarde,A.,Rozeveld,D.,Van Oosterhout,A. J.,Heijink,I. H.,Castelli,R.,。。。Elsinga,P. H.(2015)。,MicroPET evaluation of a hydroxamate-based MMP inhibitor, [F]FB-ML5, in a mouse model of cigarette smoke-induced acute airway inflammation., Molecular Imaging and Biology : MIB : The Official Publication of the Academy of Molecular Imaging, doi:10.1007/s11307-015-0847-3 [doi]
    Mlera, L., Meade-White, K., Saturday, G., Scott, D., & Bloom, M. E. (2017).,培养Powassan病毒感染在Peromyscus Leucopus,自然宿主。,Plos忽略了热带疾病,11(1),E0005346。DOI:10.1371 / journal.pntd.0005346 [DOI]
    Gouveia, K., & Hurst, J. L. (2017).,Optimising reliability of mouse performance in behavioural testing: The major role of non-aversive handling.,科学报告,7,44999.Doi:10.1038 / srep49999 [Doi]
    Kolosowska,Natalia;Keuters,Meike H;Wojciechowski,Sara;Keksa-goldsteine,velta;Laine,Mika;麦芽,塔拉;Goldsteins,Gundars;Koistinaho,贾里;德文达,弘南,IL-13的外周给药诱导抗炎微胶质/巨噬细胞反应,并在缺血性卒中提供神经保护。,神经治疗方法:美国实验神经治疗股份有关会杂志Vol.37,2019
    Draijer,C.,Boorsma,C. E.,Reker-Smit,C.,Post,E.,Poelstra,K。,&Melgert,B. N.(2016),PGE2治疗的巨噬细胞抑制小鼠中过敏性肺炎的发育。,白细胞生物学杂志,100(1),95-102。DOI:10.1189 / jlb.3mab1115-505r [doi]
    Santio,N. M.,Eerola,S.K。,Paatero,I.,Yli-Kauhaloma,J.,Anizon,F.,Moreau,P.,。。。Koskinen,P. J.(2015),PIM激酶促进前列腺癌异种移植物的迁移和转移性生长,PLO 1,10(6),E0130340。DOI:10.1371 / journal.pone.0130340 [DOI]
    Kirchner,J.,Hackbarth,H.,Stelzer,H. D. D.,&Tsai,P. P.(2012)。,Preferences of group-housed female mice regarding structure of softwood bedding.,实验动物,46(2),95-100。DOI:10.1258 / LA.2011.010173 [DOI]
    Grosso-Becerra, M. V., Santos-Medellin, C., Gonzalez-Valdez, A., Mendez, J. L., Delgado, G., Morales-Espinosa, R., . . . Soberon-Chavez, G. (2014),假单胞菌铜绿假单胞菌临床和环境分离株构成了一种高表型多样性的人口。, BMC Genomics, 15, 318-2164-15-318. doi:10.1186/1471-2164-15-318 [doi]
    罗兰,马里昂;M Dougall,Annette;Javaux,Justine;Lallemand,François;Machiels,Bénédicte;翡翠,菲律宾;脱像,本杰明G;,单核细胞的肝巨噬细胞的募集是独立于IL-4R ??但与血吸虫病中的常规巨噬细胞消融有关。, European journal of immunology Vol.49, 2019
    Hofmann, S., Hilbe, M., Fajardo, R. J., Hagenmuller, H., Nuss, K., Arras, M., . . . Meinel, L. (2013).,Remodeling of tissue-engineered bone structures in vivo.。欧洲药学医学与生物食品学杂志:官方arbeitsgemeinschaft fur Pharmazeutische verfahrenstechnik E.v,85(1),119-129。DOI:10.1016 / J.EJPB.2013.02.011 [DOI]
    Percie du Sert N, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Hurst V, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T, Würbel H.,Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0,plos biol。2020年7月14日; 18(7):E3000411。DOI:10.1371 / journal.pbio.3000411。Ecollection 2020 Jul。
    Wirz, A., Mandillo, S., D'Amato, F. R., Giuliani, A., & Riviello, M. C. (2015),在C57BL / 6J和BALB / C小鼠中对小鼠房屋的响应,使用和习惯。,实验动物/日本实验室动物科学协会,64(3),281-293。DOI:10.1538 / Expanim.14-0104 [DOI]
    玛丽亚麦尔姆;Diessner, André; Tamminen, Kirsi; Liebscher, Markus; Vesikari, Timo; Blazevic, Vesna;,Rotavirus vp6作为在尼累累的诺育尼亚人生成的二价诺病毒疫苗的佐剂。, Pharmaceutics Vol.11, 2019
    OhiaNwoko,O.,Haile,C。N、 ,&Kosten,T。答(2017).,Sex differences in the acute locomotor response to methamphetamine in BALB/c mice.《行为大脑研究》,327,94-97。doi:S0166-4328(16) 31259-1[pii]
    纳瓦卡斯特罗,凯伦伊丽莎白;Solleiro-Villavicencio,海伦娜;Río-araiza,Víctorhugo del;塞戈维亚 - 门多萨,玛丽安娜;Pérez-Torres,Armando;Morales-Montor,Jorge,小鼠Trichinella螺肠道肠道感染早期双酚的性质相关保护作用,Plos一卷第14卷,2019
    van den Berg, W. E., Lamballais, S., & Kushner, S. A. (2015).,老鼠中社会等级的性别特定机制。,神经咽蓟省医生:美国神经咽部学院的正式出版物,40(6),1364-1372。DOI:10.1038 / NPP.2014.319 [DOI]
    Hoverkamp,A.,Thijssen,S.,Van Vlies,N.,&Garssen,J.(2015)。,用Nongigosible低聚糖的特定混合物补充孕鼠减少了雄性后代过敏性哮喘的症状。, The Journal of Nutrition, 145(3), 640-646. doi:10.3945/jn.114.197707 [doi]
    克莱纳,G.,西西,F.,特里科,P。M、 ,Zacchigna,S.,Crovella,S.,&Marzuzzi,A(2013).,Systemic and neuronal inflammatory markers in a mouse model of mevalonate kinase deficiency: A strain-comparative study.,体内(雅典,希腊),27(6),715-722。DOI:27/6/715 [PII]
    Milani C,Farina F,Botto L,Massimino L,Lonati E,Donzelli E,Ballarini E,Creppa L,Marmiroli P,Bulbarelli A,Palesti P.,Systemic Exposure to Air Pollution Induces Oxidative Stress and Inflammation in Mouse Brain, Contributing to Neurodegeneration Onset,int j mol sci。2020年5月24日; 21(10):3699。DOI:10.3390 / IJMS21103699
    Neill,D. R.,Fernandes,V. E.,Wisby,L.,Haynes,A. R.,Ferreira,D. M.,Laher,A.,。。。安德鲁,P. W.(2012)。,T调节细胞控制小鼠中侵入性肺炎球菌的敏感性。, PLoS Pathogens, 8(4), e1002660. doi:10.1371/journal.ppat.1002660 [doi]
    Kemper, K., Rodermond, H., Colak, S., Grandela, C., & Medema, J. P. (2012).,Targeting colorectal cancer stem cells with inducible caspase-9, Apoptosis : An International Journal on Programmed Cell Death, 17(5), 528-537. doi:10.1007/s10495-011-0692-z [doi]
    Isern,E.,Gustems,M.,Messerle,M.,Borst,E.,Ghazal,P.,&Angulo,A.(2011)。,活化剂蛋白1在人巨细胞病毒主要直接 - 早期增强剂内的结合基序在功能上是冗余的,并且在急性感染期间以NF-{kappa} B源以合作方式作用。, Journal of Virology, 85(4), 1732-1746. doi:10.1128/JVI.01713-10 [doi]
    Neill, D. R., Saint, G. L., Bricio-Moreno, L., Fothergill, J. L., Southern, K. W., Winstanley, C., . . . Flanagan, B. F. (2014).,B淋巴细胞分化因子(BAFF)在CF和CF的肺部的呼吸道中表达,感染假单胞菌铜绿假单胞菌的小鼠肺部,plos一个,9(5),E95892。DOI:10.1371 / journal.pone.0095892 [DOI]
    Fernandes VE, Ercoli G, Bénard A, Brandl C, Fahnenstiel H, Müller-Winkler J, Weber GF, Denny P, Nitschke L, Andrew PW.,B细胞抑制受体CD22是脑膜炎肺炎链球菌感染的主要因素,PLoS病理。2020年4月23日;16(4):e1008464。doi:10.1371/journal.ppat.1008464。eCollection 2020年4月。
    Spencer, A. J., Longley, R. J., Gola, A., Ulaszewska, M., Lambe, T., & Hill, A. V. (2017).,The threshold of protection from liver-stage malaria relies on a fine balance between the number of infected hepatocytes and effector CD8(+) T cells present in the liver, Journal of Immunology (Baltimore, Md.: 1950), 198(5), 2006-2016. doi:10.4049/jimmunol.1601209 [doi]
    Wong,S. H.,Walker,J.A.,Jolin,H. E.,Drynan,L. F.,火腿,E.,Camelo,A.,。。。McKenzie,A. N.(2012)。,转录因子Roralpha对Nuocyte发育至关重要。, Nature Immunology, 13(3), 229-236. doi:10.1038/ni.2208 [doi]
    Craig,M.,Sadik,A. Y.,Golubeva,Y。,Tidhar,A.,&Slauch,J. M.(2013),Twin-arginine translocation system (tat) mutants of salmonella are attenuated due to envelope defects, not respiratory defects., Molecular Microbiology, 89(5), 887-902. doi:10.1111/mmi.12318 [doi]
    Tsai,P.P.,Nagelschmidt,N.,Kirchner,J.,Stelzer,H. D.,&Hackbarth,H.(2012)。,Validation of an automatic system (DoubleCage) for detecting the location of animals during preference tests., Laboratory Animals, 46(1), 81-84. doi:10.1258/la.2011.011072 [doi]
    Yu,I. T.,Park,J. Y.,Kim,S. H.,Lee,J. S.,Kim,Y. S.,H.,H.(2009),通过与H4乙酰化相关的散文因子诱导散对因子促进神经元分化,神经药物,56(2),473-480。DOI:10.1016 / J.Neuropharm.2008.09.019 [DOI]

    传染病

    Tan T K, Rijal P, Rahikainen R, Keeble A H, Schimanski L, Hussain S, Harvey R, et al.,使用SARS-COV-2穗蛋白受体结合结构域的截止物多聚化的Covid-19疫苗候选者诱导有效的中和抗体应答,Biorxiv 2020.08.31.275701;DOI:https://doi.org/10.1101/2020.08.31.275701
    Dinnon Kh第3,Leist SR,SchäferA,爱德华州Ce,Martinez Dr,Montgomery Sa,West A,Yount Bl Jr,Hou Yj,Adams Le,Gully Kl,Brown Aj,Huang E,Bryant Md,Choong Ic,Glenn JS,格罗斯基·勒,切山TP,律师卢比。SARS-COV-2的鼠标适应模型,以测试Covid-19对策, 自然。2020 Oct;586(7830):560-566. doi: 10.1038/s41586-020-2708-8. Epub 2020 Aug 27.
    Leist SR, Dinnon KH 3rd, Schäfer A, Tse LV, Okuda K, Hou YJ, West A, Edwards CE, Sanders W, Fritch EJ, Gully KL, Scobey T, Brown AJ, Sheahan TP, Moorman NJ, Boucher RC, Gralinski LE, Montgomery SA, Baric RS.,A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice, 细胞。2020 Nov 12;183(4):1070-1085.e12. doi: 10.1016/j.cell.2020.09.050. Epub 2020 Sep 23.
    Schäfer A, Muecksch F, Lorenzi JCC, Leist SR, Cipolla M, Bournazos S, Schmidt F, Maison RM, Gazumyan A, Martinez DR, Baric RS, Robbiani DF, Hatziioannou T, Ravetch JV, Bieniasz PD, Bowen RA, Nussenzweig MC, Sheahan TP.,Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo,J Exp Med。2021年3月1日;218(3):E202011993。doi:10.1084/jem.20201993。
    Van Doremalen N,Lambe T,Spencer A,Belij-Rammerstorfer S,Purushotham Jn,Port JR,Avanzato VA,Bushmaker T,Flaxman A,Ulaszewska M,Feldmann F,Allen ER,Sharpe H,Schulz J,Holbrook M,Okumura A.,Meade-White K,Pérez-PérezL,爱德华兹NJ,Wright D,Bissett C,Gilbride C,Williamson BN,Rosenke R,Long D,Ishwarbhai A,Kailath R,Rose L,Morris S,Powers C,Lovaglio J,Hanley PW,Scott D,星期六G,De Wit E,Gilbert Sc,Munster VJ。,Chadox1 Ncov-19疫苗可防止SARS-COV-2在恒河猕猴中的肺炎, 自然。2020年10月; 586(7830):578-582。DOI:10.1038 / s41586-020-2608-y。EPUB 2020 7月30日。
    Menachery VD,Gralinski Le,Mitchell HD,Dinnon Kh 3,Leist SR,Yount Bl Jr,Mcanarney et,Graham Rl,Waters Km,律师卢比。,联合衰减为减毒活冠状病毒疫苗提供了策略,j病毒。2018年8月16日; 92(17):E00710-18。DOI:10.1128 / JVI.00710-18。印刷2018年9月1日。
    Peniche AG,Osorio Ey,Melby PC,Travi BL。,组胺H1受体拮抗剂偶氮物和FexofeNAine对皮肤Leishmania的功效疗效,plos opprop top。2020 8月10日; 14(8):E0008482。DOI:10.1371 / journal.pntd.0008482。Ecollection 2020 8月
    李W,Schäfera,kulkarni ss,liu x,martinez博士,陈c,sun z,leiss sr,德利奇a,张l,ura ml,berezuk a,chittori s,Leopold k,mannar d,srivastava ss,zhu x,彼得森欧共体,曾康,梅勒斯JW,Falzarano D,Subramaniam S,律师Rs,Dimitrov DS。,High Potency of a Bivalent Human V(H) Domain in SARS-CoV-2 Animal Models, 细胞。2020年10月15日; 183(2):429-441.E16。DOI:10.1016 / J.Cell.2020.09.007。EPUB 2020 SEP 4。
    Lainš?ek D, Fink T, Forstneri?, et al.,基于不同类型的SARS-COV-2穗蛋白的不同类型的纳米形型RBD结构域对疫苗候选的免疫反应,bioRxiv 2020.08.28.244269;内政部:https://doi.org/10.1101/2020.08.28.244269
    Capone S,Raggioli A,Gentile M等人,Immunogenicity of a new gorilla adenovirus vaccine candidate for COVID-19, bioRxiv 2020.10.22.349951; doi: https://doi.org/10.1101/2020.10.22.349951
    Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Nkolola JP, Schäfer A, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Martinez DR, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Shrihari S, Mueller BK, Meiler J, Chandrashekar A, Mercado NB, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, McCune BT, Keeler SP, Holtzman MJ, Barouch DH, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE Jr.,Potently neutralizing and protective human antibodies against SARS-CoV-2, 自然。2020 Aug;584(7821):443-449. doi: 10.1038/s41586-020-2548-6. Epub 2020 Jul 15.
    李W,陈C,德利奇A,马丁内斯博士,格拉林斯基·勒,孙Z,SchäferA,Kulkarni SS,刘X,leistSr,zhelev dv,zhang l,金yj,Peterson ec,Conard A,Mellors JW,Tseng CK,falzarano d,arric rs,dimitrov ds。,Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection, Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29832-29838. doi: 10.1073/pnas.2010197117. Epub 2020 Nov 2.
    Peterson NC, Berlin AA.,Risk Assessment for Use of a Porcine Circovirus-Contaminated Reagent in a Barrier Maintained Rodent Colony,J Am Assoc Anim Sci。2020年9月1日; 59(5):575-579。DOI:10.30802 / AALAS-JAALAS-20-000012。EPUB 2020 6月30日。
    Solana JC, Ramírez L, Cook EC, Hernández-García E, Sacristán S, Martín ME, Manuel González V, Reguera RM, Balaña-Fouce R, Fresno M, Requena JM, Iborra S, Soto M.,利什曼原虫HSP70-II突变株皮下免疫可降低BALB/c小鼠内脏利什曼病的严重性,疫苗(巴塞尔)。2020 3月23日; 8(1):141。DOI:10.3390 /疫苗80141。

    单克隆抗体

    Coutant,F.,Sanchez David,R. Y.,Felix,T.,Boulay,A.,Calechurn,L.,Souque,P.,。。。Charneau,P。(2012)。,非含有的慢病毒载体的疫苗为疟疾提供了长期无菌保护。,Plos一个,7(11),E48644。DOI:10.1371 / journal.pone.0048644 [DOI]
    Reggiani,F.,Labanca,V.,Mancuso,P.,Rabascio,C.,Talarico,G.,Orecchioni,S。。。。Bertolini,F.(2017)。,Adipose progenitor cell secretion of GM-CSF and MMP9 promotes a stromal and immunological microenvironment that supports breast cancer progression,癌症研究,77(18),5169-5182。DOI:10.1158 / 0008-5472.CAN-17-0914 [DOI]
    Borges,O.,Silva,M.,De Sousa,A.,Borchard,G.,Junginger,H. E.,&Cordeiro-Da-Silva,A.(2008)。,藻酸盐涂覆的壳聚糖纳米粒子是乙型肝炎表面抗原的有效皮下佐剂。,国际免疫医药武装学,8(13-14),1773-1780。DOI:10.1016 / J.Intimp.2008.08.013 [DOI]
    Aranda, J., Garrido, M. E., Cortes, P., Llagostera, M., & Barbe, J. (2008).,三种阳离子条件下诱导三链球菌蛋白的保护能力分析。, Infection and Immunity, 76(4), 1590-1598. doi:10.1128/IAI.00987-07 [doi]
    罗伯茨,A.,拉米兰德,E。W、 ,Vogel,L.,Jackson,J。P、 ,围场,C。D、 ,Guardner,J。子带,K(2008).,用于SARS-COV感染的动物模型和疫苗。,病毒研究,133(1),20-32。DOI:S0168-1702(07)00113-X [PII]
    Dobbs,N.A.,Zhou,X.,Pulse,M.,Hodge,L. M.,Schoeb,T. R.,&Simecka,J.W。(2014),Antigen-pulsed bone marrow-derived and pulmonary dendritic cells promote Th2 cell responses and immunopathology in lungs during the pathogenesis of murine mycoplasma pneumonia.,免疫学杂志(巴尔的摩,MD:1950),193(3),1353-1363。DOI:10.4049 / Jimmunol.1301772 [Doi]
    Di尼罗、R。齐勒尔称,F。,御马,F。,Crovella S。, Stebel, M., Bestagno, M., . . . Sblattero, D. (2007),用于动物模型人类自身免疫疾病体内体内研究的施工,BMC生物技术,7,46。doi:1472-6750-7-46 [pii]项目
    Aranda,J.,Cortes,P.,Garrido,M. E.,Fittipaldi,N.,Llagostera,M.,Gottschalk,M.,&Barbe,J.(2009)。,Feob Transporter对链球菌毒力的贡献。国际微生物学是,西班牙微生物学会官方杂志,12(2),137-143。DOI:IM2306131 [PII]
    Kapur, R., Heitink-Polle, K. M., Porcelijn, L., Bentlage, A. E., Bruin, M. C., Visser, R., . . . Vidarsson, G. (2015).,C-reactive protein enhances IgG-mediated phagocyte responses and thrombocytopenia., Blood, 125(11), 1793-1802. doi:10.1182/blood-2014-05-579110 [doi]
    Harey,C.J.,Elsner,R. A.,Barthold,S. W.,&Baumgarth,N。(2012)。,延迟和转移标志着B细胞对勃艮第鲍力士感染的反应发展。,免疫学杂志(巴尔的摩,MD。:1950),188(11),5612-5622。DOI:10.4049 / Jimmunol.1103735 [Doi]
    Pent,B. D. D.,Hester,S. N.,Donovan,S. M.和Woods,J.A.(2012),Dietary whole glucan particles do not affect antibody or cell-mediated immune responses to influenza virus vaccination in mice.,免疫研究,41(3),275-289。DOI:10.3109 / 08820139.2011.628732 [DOI]
    Erova, T. E., Rosenzweig, J. A., Sha, J., Suarez, G., Sierra, J. C., Kirtley, M. L., . . . Chopra, A. K. (2013).,鉴赏外膜蛋白抗原作为新一代重组瘟疫疫苗的候选者的保护潜力评价。,临床和疫苗免疫学:CVI,20(2),227-238。DOI:10.1128 / CVI.00597-12 [DOI]
    veCeric-aler,Z.,Erman,A.,Cerar,A.,Motaln,H.,Kolosa,K。,Lah Turnsek,T.,。。。Perse,M。(2016)。,提高脐带干细胞移植对抗静电细胞球蛋白预处理的小鼠顺铂诱导肾损伤的改善,干细胞国际,2016,3585362.Doi:10.1155 / 2016/3585362 [Doi]
    Cabrera,M.,Pewe,L.L.L.,Harty,J.T.,&Fresftt,U.(2013),In vivo CD8+ T cell dynamics in the liver of plasmodium yoelii immunized and infected mice,Plos一个,8(8),E70842。DOI:10.1371 / journal.pone.0070842 [DOI]
    Aranda,J.,Teixido,L.,Fittipaldi,N.,Cortes,P.,Llagostera,M.,Gottschalk,M.,&Barbe,J.(2012)。,编码锌结合脂蛋白103的基因的失活损害了链球菌的感染性。,加拿大兽医研究杂志= Revue Canadienne de Recherche Veterinaire,76(1),72-76。
    De Witte,C.,Taminiau,B.,Flahou,B.,Hautekiet,V.,Daube,G.,Ducatelle,R.,&Haesbrouck,F。(2018),饲料琥珀霉素用药诱导抗炎作用,并防止椎管细胞损失,而不会影响小鼠胃中的肠道肠道殖民化。, Veterinary Research, 49(1), 35-018-0530-1. doi:10.1186/s13567-018-0530-1 [doi]
    Terwisscha van Scheltinga, A. G., van Dam, G. M., Nagengast, W. B., Ntziachristos, V., Hollema, H., Herek, J. L., . . . de Vries, E. G. (2011).,术中近红外荧光肿瘤成像与血管内皮生长因子和人表皮生长因子受体2靶向抗体。, Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 52(11), 1778-1785. doi:10.2967/jnumed.111.092833 [doi]
    Mastelic Gavillet,B.,Eberhardt,C. S.,奥斯特,F.,Castellino,F.,Seubert,A。,Tregoning,J. S.,。。。Siegrist,C. A.(2015),MF59通过促进T卵泡辅助细胞,从而在成人和早期生命中的发芽中心反应介导其B细胞辅助性。, Journal of Immunology (Baltimore, Md.: 1950), 194(10), 4836-4845. doi:10.4049/jimmunol.1402071 [doi]
    Kemper,K.,Prasetyanti,P. R.,De Lau,W.,罗德美德,H.,Clevers,H.,&Medema,J.P.(2012)。,对Lgr5的单克隆抗体鉴定人结肠直肠癌干细胞,干细胞(Dayton,Ohio),30(11),2378-2386。DOI:10.1002 / Stew.1233 [DOI]
    Bubeck Wardenburg,J.,Palazzolo-Ballance,A. M.,Otto,M.,Schneewind,O.,&Deleo,F. R.(2008)。,Panton-valentinene白毛蛋白不是群体相关甲氧西蛋白抗金黄色葡萄球菌病的鼠模型中的毒力决定因素。,传染病杂志,198(8),1166-1170。DOI:10.1086 / 592053 [DOI]
    Cray,C.,贝塞尔森,D. G.,Hart,J.L.,Yoon,D.,Rodriguez,M.,Zaias,J.,&Altman,N.H。(2010年)。,急性期蛋白和蛋白质电泳在实验和天然感染小鼠中监测急性炎症过程的定量,比较医学,60(4),263-271。
    odeh,A. N.,&Simecka,J. W.(2016)。,调节CD4 + CD25 + T细胞抑制小鼠支原体肺炎的炎症疾病,促进IL-17和IFN-Gamma反应。,PLO 1,11(5),E0155648。DOI:10.1371 / journal.pone.0155648 [DOI]
    Jahagirar,R.,attwell,S.,Marusic,S.,Bendele,A.,Shenoy,N.,Mclure,K。G.,。。。Kulikowski,E。(2017)。,RVX-297, a BET bromodomain inhibitor, has therapeutic effects in preclinical models of acute inflammation and autoimmune disease., Molecular Pharmacology, 92(6), 694-706. doi:10.1124/mol.117.110379 [doi]
    Elhaik Goldman,S.,Dotan,S.,Talias,A.,Lilo,A.,Azriel,S.,Malka,I.,。。。Mizrachi Nebenzahl,Y.(2016)。,蛋白疫苗候选菌株肺炎链球菌果糖-1,6-二磷酸醛缩酶(streptoccuseuccuseuccuseumonicus,果糖-1,6-二磷酸醛缩酶)诱导Th1/Th2/Th17型细胞因子反应。,国际分子医学杂志,37(4),1127-1138。DOI:10.3892 / IJMM.2016.2512 [DOI]
    Rockx, B., Corti, D., Donaldson, E., Sheahan, T., Stadler, K., Lanzavecchia, A., & Baric, R. (2008),有效交叉中和人单克隆抗体保护对抗致命性致命性和人畜共患急性呼吸综合征冠状病毒攻击的结构基础,病毒学杂志,82(7),3220-3235。DOI:10.1128 / JVI.02377-07 [DOI]
    Hernandez, J. L., Padilla, L., Dakhel, S., Coll, T., Hervas, R., Adan, J., . . . Messeguer, R. (2013).,Therapeutic targeting of tumor growth and angiogenesis with a novel anti-S100A4 monoclonal antibody.,Plos一个,8(9),E72480。DOI:10.1371 / journal.pone.0072480 [DOI]
    Kuck,L. R.,Byrne-Nash,R.,Gillis,J.,Bueter,K。,Couzens,L.K.,Eichelberger,M. C. C.,&Rowlen,K. L.(2018)。,VaxArray for hemagglutinin and neuraminidase potency testing of influenza vaccines., Vaccine, 36(21), 2937-2945. doi:S0264-410X(18)30545-0 [pii]

    Oncology

    Karp NA, Wilson Z, Stalker E, Mooney L, Lazic SE, Zhang B, Hardaker E.,多批次设计,提供有效性的稳健估计并减少动物使用——一个同源肿瘤案例研究,SCI代表。2020年4月10日; 10(1):6178。DOI:10.1038 / S41598-020-62509-7。
    Forte, B. L., Slosky, L. M., Zhang, H., Arnold, M. R., Staatz, W. D., Hay, M., . . . Vanderah, T. W. (2016).,血管紧张素 - (1-7)/ MAS受体作为癌症诱导的骨疼痛的抗闭合症剂。, Pain, 157(12), 2709-2721. doi:10.1097/j.pain.0000000000000690 [doi]
    Bonavita E, Bromley CP, Jonsson G, Pelly VS, Sahoo S, Walwyn-Brown K, Mensurado S, Moeini A, Flanagan E, Bell CR, Chiang SC, Chikkanna-Gowda CP, Rogers N, Silva-Santos B, Jaillon S, Mantovani A, Reis E Sousa C, Guerra N, Davis DM, Zelenay S.,Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade, Immunity. 2020 Dec 15;53(6):1215-1229.e8. doi: 10.1016/j.immuni.2020.10.020. Epub 2020 Nov 20.
    怒族ñez Rivera A,Fournier PGJ,Arelano DL,RodriguezHernandez AG,Vazquez Duhalt R,Cadena Nava路。,用于生物医学目的的Brome马赛克病毒样颗粒作为siRNA纳米载体, Beilstein J Nanotechnol. 2020 Feb 20;11:372-382. doi: 10.3762/bjnano.11.28. eCollection 2020.
    Arroyo-Crespo, Juan J; Armiñán, Ana; Charbonnier, David; Deladriere, Coralie; Palomino-Schätzlein, Martina; Lamas-Domingo, Rubén; Forteza, Jerónimo; Pineda-Lucena, Antonio; Vicent, María J,Characterization of triple-negative breast cancer preclinical models provides functional evidence of metastatic progression.,国际癌症杂志Vol.145,2019
    TeijeiraÁ,Garasa S,Gato M,Alfaro C,Migueliz I,Cirella A,De Andrea C,Ochoa MC,Otano I,Etxeberria I,Andueza MP,Nieto CP,Resano L,Azpilikueta A,Allegretti M,De Pizzol M,De Pizzol M,Ponz-sarvisém,rouzaut a,Sanmamed Mf,Schalper K,Carleton M,Mellado M,Rodriguez-Ruiz Me,Berraondo P,Perez-Gracia JL,Melero I.,CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity, Immunity. 2020 May 19;52(5):856-871.e8. doi: 10.1016/j.immuni.2020.03.001. Epub 2020 Apr 13.
    法尔沃P、OreChioni S、Hillje R、Ravane A、Mancuso P、Camisaschi C、Luzi L、Pelicci P、Bertolini F。,Cyclophosphamide and vinorelbine activate stem-like CD8+ T cells and improve anti-PD-1 efficacy in triple-negative breast cancer, Cancer Res. 2020 Dec 2:canres.1818.2020. doi: 10.1158/0008-5472.CAN-20-1818. Online ahead of print.
    Shamni, Ofer; Grievink, Hilbert; Itamar, Batel; Mishani, Eyal; Abourbeh, Galith;,EAGFR突变阳性NSCLC宠物成像的ERLOTINIB氟化类似物的研制,分子成像和生物学Vol.21,2019
    Subs Fv,邱Sq,yim Jj,Schrödercp,Timmer-Bosscha H,Bensen Es,Santini JT JR,De Vries Ege,Bogyo M,Van Dam Gm。,Fluorescent image-guided surgery in breast cancer by intravenous application of a quenched fluorescence activity-based probe for cysteine cathepsins in a syngeneic mouse model,ejnmmi res。2020年9月29日; 10(1):111。DOI:10.1186 / s13550-020-00688-0
    Rivera-Huerta, M., Lizarraga-Grimes, V. L., Castro-Torres, I. G., Tinoco-Mendez, M., Macias-Rosales, L., Sanchez-Bartez, F., . . . Gracia-Mora, M. I. (2017).,Functional effects of prebiotic fructans in colon cancer and calcium metabolism in animal models., BioMed Research International, 2017, 9758982. doi:10.1155/2017/9758982 [doi]
    Sanchez-Gonzalez,B.,Garcia-Vazquez,F. J.,Farfan-Morales,J. E.,&Jimenez-Zamudio,L. A.(2015)。,Increased NHC cells in the peritoneal cavity of plasmacytoma susceptible BALB/c mouse.,炎症的介质,2015,313140. DOI:10.1155 / 2015/313140 [DOI]
    Kranjc Brezar S,Mraak V,Bosnjak M,Savarin M,Sersa G,Cemazar M.,质粒DNA的肿瘤瘤基因电转样编码ShRNA对黑色素瘤细胞粘附分子通过抗衰血效应和免疫应答的激活来放射抗性肿瘤,疫苗(巴塞尔)。2020 3月19日; 8(1):135。DOI:10.3390 /疫苗8010135。
    Alessandri,Giulio;Coccè,瓦伦蒂娜;牧师,法比奥;Paroni,丽塔;Dei Cas,米歇尔;弗朗切斯科·埃特雷利;Pollo,Bianca;Gatti,Laura;颤音,卡洛;Berenzi,angiola; Parati, Eugenio; Brini, Anna Teresa; Bondiolotti, Gianpietro; Ponzoni, Mirco; Pessina, Augusto,Microfragmented human fat tissue is a natural scaffold for drug delivery: Potential application in cancer chemotherapy., Journal of controlled release : official journal of the Controlled Release Society Vol.302, 2019
    Bach-Griera M, Campo-Pérez V, Barbosa S, Traserra S, Guallar-Garrido S, Moya-Andérico L, Herrero-Abadía P, Luquin M, Rabanal RM, Torrents E, Julián E.,Mycolicibacterium Brumae是一种安全和无毒的癌症治疗免疫调节剂,疫苗(巴塞尔)。2020年4月25日; 8(2):198。DOI:10.3390 /疫苗8020198。
    Raineri D, Dianzani C, Cappellano G, Maione F, Baldanzi G, Iacobucci I, Clemente N, Baldone G, Boggio E, Gigliotti CL, Boldorini R, Rojo JM, Monti M, Birolo L, Dianzani U, Chiocchetti A.,Osteopontin结合icosl促进肿瘤转移,公共生物。2020年10月26日; 3(1):615。DOI:10.1038 / S42003-020-01333-1。
    Di Tano M,Raucci F,Vernieri C,Caffa I,Buono R,Fanti M,Brandhorst S,Curigliano G,Necioni A,De Brud F,Longo VD。,禁食饮食与维生素C对抗KRAS突变癌的协同效应,Nat Communce。2020年5月11日; 11(1):2332。DOI:10.1038 / S41467-020-16243-3。
    Pfitzer,丽莎;克里斯蒂娜•莫泽;Gegenfurtner,弗洛rian; Arner, Anja; Foerster, Florian; Atzberger, Carina; Zisis, Themistoklis; Kubisch-Dohmen, Rebekka; Busse, Johanna; Smith, Rebecca,靶向肌动蛋白抑制多柔比星诱导的DNA损伤的修复:一种新的组合治疗治疗方法。, Cell death & disease Vol.10, 2019
    Drescher F, Juárez P, Arellano DL, Serafín-Higuera N, Olvera-Rodriguez F, Jiménez S, Licea-Navarro AF, Fournier PG.,TIE2 Induces Breast Cancer Cell Dormancy and Inhibits the Development of Osteolytic Bone Metastases, Cancers (Basel). 2020 Apr 3;12(4):868. doi: 10.3390/cancers12040868.
    阮,o . N。格林,C,施耐德,l·S。曹,Y. K., Atzberger, C., Bartel, K., . . . Vollmar, A. M. (2017),双孔通道功能对于侵袭性癌细胞迁移至关重要。, Cancer Research, 77(6), 1427-1438. doi:10.1158/0008-5472.CAN-16-0852 [doi]
    Allen KL,Cann J,Zhao W,Peterson N,Lazzaro M,Zhong H,Wu H,Dall'Acqua Wf,Borrok MJ,Damschroder MM,Tsui P,Li Q.,Upregulation of annexin A1 protein expression in the intratumoral vasculature of human non-small-cell lung carcinoma and rodent tumor models,plos一个。2020年6月4日; 15(6):E0234268。DOI:10.1371 / journal.pone.0234268。ecollection 2020。

    Pharmacology

    Narra, H. P., Shubitz, L. F., Mandel, M. A., Trinh, H. T., Griffin, K., Buntzman, A. S., . . . Orbach, M. J. (2016),氟氯酰亚胺POSADASII CPS1缺失突变体是无毒的,免受致死感染的小鼠。,感染和免疫,84(10),3007-3016。DOI:10.1128 / IAI.00633-16 [DOI]
    Hirschberg,H.,Van Kuijk,S.,Loch,J.,Jiskoot,W.,Bouwstra,J.,Kersten,G.,&Amorij,J.P.(2012)。,囊泡制剂和微针阵列的组合方法,用于对乙型肝炎病毒的经皮免疫免疫。,欧洲医药科学杂志:欧洲医药科学联合会官方杂志,46(1-2),1-7。DOI:10.1016 / J.EJPS.2012.01.013 [DOI]
    棉铃,M.,德明,D.,Long,K.,Agnihothram,S.,Whitmore,A.,Ferris,M。,。。。律师,R. S.(2011)。,A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge., Journal of Virology, 85(23), 12201-12215. doi:10.1128/JVI.06048-11 [doi]
    Cestari,I.,Kalidas,S.,Monnerat,S.,Anupama,A.,Phillips,M. A.,&Stuart,K。(2013)。,一种多氨基酰基tRNA合成酶复合物,可增强非洲锥虫tRNA氨基酰化。,分子和细胞生物学,33(24),4872-4888。DOI:10.1128 / MCB.00711-13 [DOI]
    Sweeney, F. F., O'Leary, O. F., & Cryan, J. F. (2014).,Activation but not blockade of GABAB receptors during early-life alters anxiety in adulthood in BALB/c mice., Neuropharmacology, 81, 303-310. doi:10.1016/j.neuropharm.2013.08.039 [doi]
    Ferrini E,MeCozzi L,Corsi L,Ragionieri L,Donofrio G,Stellari FF。,阿尔法松和德Xmedetomidine作为气体麻醉用于博来霉素诱导的肺纤维化鼠模型的微型CT肺成像的替代品, Front Vet Sci. 2020 Oct 8;7:588592. doi: 10.3389/fvets.2020.588592. eCollection 2020.
    Movellan,J.,Urban,P.,Moles,E.,De La Fuente,J.M.,Sierra,T.,Serrano,J.L,&Fernandez-Busquets,X.(2014)。,Amphiphilic dendritic derivatives as nanocarriers for the targeted delivery of antimalarial drugs.,生物材料,35(27),7940-7950。DOI:10.1016 / J.Biomaterials.2014.05.061 [DOI]
    NovoA,E. M.,Camacho,N.,Tor,A.,Wilkinson,B.,Moss,S.,S.,Marin-Garcia,P.,。。。Ribas de Pouplana,L.(2014)。,天然氨基酰基-TRNA合成酶抑制剂在体内清除疟疾的类似物。《美利坚合众国国家科学院学报》,111(51),E508-17。doi:10.1073/pnas.1405994111 [内政部]
    Savignac,H. M.,Kiely,B.,Dinan,T.G.,&Cryan,J.F。(2014)。,双歧杆菌对BALB / C小鼠的应力相关行为和生理学产生应变特异性效果。,神经科学生学和摩托车:欧洲胃肠运动会的官方杂志,26(11),1615-1627。DOI:10.1111 / NMO.12427 [DOI]
    Savignac, H. M., Tramullas, M., Kiely, B., Dinan, T. G., & Cryan, J. F. (2015).,双歧杆菌调节焦虑鼠标菌株中的认知过程,行为脑研究,287,59-72。DOI:10.1016 / J.BBR.2015.02.044 [DOI]
    Schnaider L,Toprakcioglu Z,EZRA A,Liu X,Bychenko D,Levin A,Gazit E,Kangle TPJ。,Biocompatible Hybrid Organic/Inorganic Microhydrogels Promote Bacterial Adherence and Eradication in Vitro and in Vivo, Nano Lett. 2020 Mar 11;20(3):1590-1597. doi: 10.1021/acs.nanolett.9b04290. Epub 2020 Feb 17.
    Felice, D., O'Leary, O. F., Pizzo, R. C., & Cryan, J. F. (2012).,GABA(B)受体的阻断增加了腹侧的神经发生,但不是背部成年海马:与抗抑郁作用的相关性。, Neuropharmacology, 63(8), 1380-1388. doi:10.1016/j.neuropharm.2012.06.066 [doi]
    Roux,C. M.,Rolan,H.G.G.G.G.,Santos,R.L.,Beremand,P. D.,Thomas,T.L.,Adams,L.G。,&Tsolis,R. M.(2007),布鲁氏菌需要功能型IV型分泌系统,以引发小鼠的天生免疫应答。,细胞微生物学,9(7),1851-1869。DOI:CMI922 [PII]
    Zogaj, X., Chakraborty, S., Liu, J., Thanassi, D. G., & Klose, K. E. (2008).,标题吐兰法兰西菌亚种的特征。novicidaⅣ型菌毛,微生物学(英国阅读),154(Pt 7),2139-2150。doi:10.1099/mic.0.2008/018077-0 [内政部]
    Liu, Y., Muir, B. W., Waddington, L. J., Hinton, T. M., Moffat, B. A., Hao, X., . . . Hughes, T. C. (2015).,胶体稳定的磁性碳纳米管在小鼠肝肿瘤中提供MRI对比度。, Biomacromolecules, 16(3), 790-797. doi:10.1021/bm501706x [doi]
    Oh, D. H., Lee, I. Y., Choi, M., Kim, S. H., & Son, H. (2012).,海马神经祖细胞促红细胞生成素(EPO)和氨基甲蛋白促红细胞生成素(CEPO)诱导的神经菌素过多的比较。, The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology, 16(4), 281-285. doi:10.4196/kjpp.2012.16.4.281 [doi]
    PérezP,MarínMQ,Lázaro-FriíasA,SorzanoCós,GómezCE,Esteban M,García-Arriaza J.,疫苗A40R基因缺失提高HIV-1疫苗候选MVA-B的免疫原性,疫苗(巴塞尔)。2020 2月6; 8(1):70。DOI:10.3390 /疫苗8010070。
    van der veen el,Subs Fv,Cleeren F,博姆斯G,Elsinga Ph,Hospers Gap,Lub-de Hooge Mn,De Vries Ege,De Vries EFJ,Antunes If.,白细胞介素-2-衍生的放射性机构对小鼠T细胞宠物成像的开发和评价,J Nucl Med。2020 SEP; 61(9):1355-1360。DOI:10.2967 / JNUMED.119.238782。EPUB 2020 2月28日。
    Azcarate,I. G.,Marin-Garcia,P.,Perez-Benavente,S.,Diez,A.,Puyet,A.,&Bautista,J. M.(2015),Early and late B cell immune responses in lethal and self-cured rodent malaria., Immunobiology, 220(5), 684-691. doi:10.1016/j.imbio.2014.11.010 [doi]
    Bjorn, C., Noppa, L., Naslund Salomonsson, E., Johansson, A. L., Nilsson, E., Mahlapuu, M., & Hakansson, J. (2015).,新型抗微生物肽PXL150在感染烧伤伤口小鼠模型中的功效和安全性。,国际抗微生物剂,45(5),519-524。DOI:10.1016 / J.IJANTIMICAG.2014.12.015 [DOI]
    Kamali, A. N., Marin-Garcia, P., Azcarate, I. G., Puyet, A., Diez, A., & Bautista, J. M. (2015).,基于抗体亲和力分离的疟原虫抗原的实验免疫。《免疫学研究杂志》,2015,723946。doi:10.1155/2015/723946 [内政部]
    Sweeney,F.F.F.,O'Leary,O. F.,&Cryan,J.F。(2013)。,Gabab受体配体在Balb / c小鼠中没有修饰条件恐惧反应。, Behavioural Brain Research, 256, 151-156. doi:10.1016/j.bbr.2013.07.035 [doi]
    Delviks-Frankenberry,K.,Paprotka,T.,Cingoz,O.,Wallt,S.,Hu,W.S.,W.S.,Coffin,J. M.,&Pathak,V. K.(2013)。,Generation of multiple replication-competent retroviruses through recombination between PreXMRV-1 and PreXMRV-2.,病毒学杂志,87(21),11525-11537。DOI:10.1128 / JVI.01787-13 [DOI]
    菲尔特贾,泡菜JC,Rusk Am,Haynes Ba,Sharp Ja,Deutsch Si。,Glycine transporter type 1 (GlyT1) inhibition improves conspecific-provoked immobility in BALB/c mice: Analysis of corticosterone response and glucocorticoid gene expression in cortex and hippocampus, Prog Neuropsychopharmacol Biol Psychiatry. 2020 Apr 20;99:109869. doi: 10.1016/j.pnpbp.2020.109869. Epub 2020 Jan 18.
    O'Connor,R.M.,Pusceddu,M.M.,O'Leary,O. F.,萨维尼克,H. M.,Bravo,J.A。,El Yacoubi,M。,。。。Cryan,J. F.(2013)。,Hippocampal group III mGlu receptor mRNA levels are not altered in specific mouse models of stress, depression and antidepressant action., Pharmacology, Biochemistry, and Behavior, 103(3), 561-567. doi:10.1016/j.pbb.2012.09.017 [doi]
    Borges,O.,Cordeiro-da-Silva,A.,Tavares,J.,Santarem,N.,De Sousa,A.,Borchard,G.,&Junginger,H. E.(2008),乙型肝炎表面抗原的鼻腔递送免疫应答,并在藻酸盐涂覆的壳聚糖纳米粒子中CPG ODN的CPG ODN。,欧洲药学学报和生物食品术学报:官方arbeitsgemeinschaft毛皮Pharmazeutische Verfahrenstechnik E.v,69(2),405-416。DOI:10.1016 / J.EJPB.2008.01.019 [DOI]
    Brickman, T. J., & Armstrong, S. K. (2007).,阿尔卡里替素施工电影利用对波尔特菌百日咳体内生长的影响。,感染和免疫,75(11),5305-5312。DOI:IAI.00849-07 [PII]
    Salomons,A. R.,Arndt,S.,&Ohl,F。(2012)。,Impact of anxiety profiles on cognitive performance in BALB/c and 129P2 mice., Cognitive, Affective & Behavioral Neuroscience, 12(4), 794-803. doi:10.3758/s13415-012-0109-7 [doi]
    Terwisscha van Scheltinga,A.G。,Lub-de Hooge,M. N.,Hinner,M.J.,Verheijen,R. B.,Allersdorfer,A.,Hulsmeyer,M。。。。Olwill,S. A.(2014),体内可视化Met肿瘤表达和抗氨基生物分布与梅特特异性抗氨基酸89ZR-PRS-110 PET示踪剂。, Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 55(4), 665-671. doi:10.2967/jnumed.113.124941 [doi]
    Savignac, H. M., Finger, B. C., Pizzo, R. C., O'Leary, O. F., Dinan, T. G., & Cryan, J. F. (2011),增加对慢性社会失败压力在天然焦急的鼠标菌株中的敏感性增加。,神经科学,192,524-536。DOI:10.1016 / J.NEUROSCICES.2011.04.054 [DOI]
    Gomez-Gallego,C.,Contado,M. C.,ILO,T.,Jaakkola,U. M.,Bernal,M.J.,Periago,M.J.,。。。Frias,R.(2012)。,Infant formula supplemented with polyamines alters the intestinal microbiota in neonatal BALB/cOlaHsd mice., The Journal of Nutritional Biochemistry, 23(11), 1508-1513. doi:10.1016/j.jnutbio.2011.10.003 [doi]
    Cestari,I.,Stuart,K。(2013年,抑制异琉酰-TRNA合成酶作为人非洲锥虫病的潜在治疗。, The Journal of Biological Chemistry, 288(20), 14256-14263. doi:10.1074/jbc.M112.447441 [doi]
    艾兹卡拉,我。G、 MarinGarcia,P.,Camacho,N.,PerezBenavente,S.,Pu尚未,A.,Diez,A。鲍蒂斯塔,J。M(2013).,抗生素Borrelidin的抗血液疟疾临床前治疗的见解。,英国药理学杂志,169(3),645-658。DOI:10.1111 / BPH.12156 [DOI]
    Marriott, H. M., Gascoyne, K. A., Gowda, R., Geary, I., Nicklin, M. J., Iannelli, F., . . . Dockrell, D. H. (2012).,Interleukin-1beta regulates CXCL8 release and influences disease outcome in response to streptococcus pneumoniae, defining intercellular cooperation between pulmonary epithelial cells and macrophages, Infection and Immunity, 80(3), 1140-1149. doi:10.1128/IAI.05697-11 [doi]
    Blockus S,Sake Sm,Wetzke M,Grethe C,Graalmann T,Pils M,Le Goffic R,Galloux M,Prochnow H,Rox K,Hüttels,Rupcic Z,Wiegmann B,Dijkman R,Rameix-Welti Ma,EléouëtJF,Duprex WP,Thiel V,Hansen G,BrönstrupM,Haid S,Pietschmann T.,Labyrinthopeptins作为呼吸道合胞病毒细胞进入的疾病抑制剂,抗病毒res。2020年5月; 177:104774。DOI:10.1016 / J.ANTIVIRAL.202020.104774。EPUB 2020 3月18日。
    Oude Munnink,T.H.,De Vries,E.G.,Vedelaar,S. R.,Timmer-Bosscha,H.,Schroder,C.P.,Brouwers,A. H.,&Lub-de Hooge,M. N.(2012)。,Lapatinib和17AAG减少89zr-Trastuzumab-F(AB')2在Skbr3肿瘤异种移植物中的摄取。, Molecular Pharmaceutics, 9(11), 2995-3002. doi:10.1021/mp3002182 [doi]
    O'Leary,O. F.,Zandy,S.,Dinan,T. G.,&Cryan,J. F.(2013)。,Lithium augmentation of the effects of desipramine in a mouse model of treatment-resistant depression: A role for hippocampal cell proliferation., Neuroscience, 228, 36-46. doi:10.1016/j.neuroscience.2012.09.072 [doi]
    O'Leary, O. F., O'Connor, R. M., & Cryan, J. F. (2012),Lithium-induced effects on adult hippocampal neurogenesis are topographically segregated along the dorso-ventral axis of stressed mice.,神经医科,62(1),247-255。DOI:10.1016 / J.Neuropharm.2011.07.015 [DOI]
    范德比尔特,A。R、 ,Terwisscha van Scheltinga,A。G、 Timmer Bosscha,H.,Schroder,C。P、 ,Pot,L.,Kosterink,J。G。雷纳,A。K(2012).,测量肿瘤VEGF-A水平,具有89 ZR-BEVACIZUMAB宠物作为早期生物标志物,用于卵巢癌异种移植模型中everolimus治疗的抗血管生成效果。, Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 18(22), 6306-6314. doi:10.1158/1078-0432.CCR-12-0406 [doi]
    Gottfries,J.,默尔,S.,&Michaelsson,E。(2012)。,Modelling of mouse experimental colitis by global property screens: A holistic approach to assess drug effects in inflammatory bowel disease., PloS One, 7(1), e30005. doi:10.1371/journal.pone.0030005 [doi]
    Bragonzi,A.(2010),Murine models of acute and chronic lung infection with cystic fibrosis pathogens,国际医学微生物学杂志:IJMM,300(8),584-593。DOI:10.1016 / J.ijmm.2010.08.012 [DOI]
    Muchnik, L., Adawi, A., Ohayon, A., Dotan, S., Malka, I., Azriel, S., . . . Nebenzahl, Y. M. (2013).,NADH氧化酶作为肺炎链球菌肺炎链球菌的粘附素,并引发小鼠的保护性免疫应答。,Plos一个,8(4),E61128。DOI:10.1371 / journal.pone.0061128 [DOI]
    Halbroth BR,Sebastian S,Salman Am,Ulaszewska M,Gola A,Longley RJ,Janse CJ,Khan Sm,Hill Av,Spencer AJ。,Preclinical Development and Assessment of Viral Vectors Expressing a Fusion Antigen of Plasmodium falciparum LSA1 and LSAP2 for Efficacy against Liver-Stage Malaria,感染免疫。2020年1月22日;88(2):e00573-19.doi:10.1128/IAI.00573-19.打印2020年1月22日。
    Flores-Villasenor,H.,Canizalez-Roman,A.,Velazquez-Roman,J.,Nazmi,K。,Bolscher,J.G。,&Leon-Sicairos,N。(2012)。,乳铁蛋白嵌合乳蛋白和牛乳铁蛋白在肠杆菌大肠杆菌O157小鼠模型中的保护作用:H7感染。, Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire, 90(3), 405-411. doi:10.1139/o11-089 [doi]
    Gomez-Gallego, C., Collado, M. C., Perez, G., Ilo, T., Jaakkola, U. M., Bernal, M. J., . . . Salminen, S. (2014).,Resembling breast milk: Influence of polyamine-supplemented formula on neonatal BALB/cOlaHsd mouse microbiota.,英国营养杂志,111(6),1050-1058。DOI:10.1017 / S0007114513003565 [DOI]
    Savignac,H. M.,Dinan,T. G.,&Cryan,J.F.(2011)。,小鼠对早期生活应激的抗性:遗传背景和应激持续时间的影响。,行为神经科学的前沿,5,13. Doi:10.3389 / Fnbeh.2011.00013 [DOI]
    England RM, Moss JI, Gunnarsson A, Parker JS, Ashford MB.,Synthesis and Characterization of Dendrimer-Based Polysarcosine Star Polymers: Well-Defined, Versatile Platforms Designed for Drug-Delivery Applications,生物大分子。2020年8月10日;21(8):3332-3341.doi:10.1021/acs.biomic.0c00768。Epub 2020年7月28日。
    莫拉莱斯,P.,Vara,D.,GomezCanas,M.,Zuniga,M。C、 ,OleaAzar,C.,Goya,P。杰格洛维奇,N(2013).,Synthetic cannabinoid quinones: Preparation, in vitro antiproliferative effects and in vivo prostate antitumor activity., European Journal of Medicinal Chemistry, 70, 111-119. doi:10.1016/j.ejmech.2013.09.043 [doi]
    Gonzalez,R.,弗林,G.,Aguilar-Melero,P.,Ranchal,I.,Linares,C。I.,Bello,R. I.,。。。Muntane,J.(2013)。,用一氧化氮供体策略靶向肝癌。,抗氧化剂和氧化还原信号,18(5),491-506。DOI:10.1089 / ARS.2011.4476 [DOI]
    Suurs FV, Lorenczewski G, Stienen S, Friedrich M, de Vries EGE, de Groot DJA, Lub-de Hooge MN.,CD3和EPCAM双特异性T细胞参与者的生物分布由CD3臂驱动,J Nucl Med。2020年11月;61(11):1594-1601.doi:10.2967/jnumed.120.241877。Epub 2020年4月13日。
    Aranda,J.,Garrido,M. E.,Fittipaldi,N.,Cortes,P.,Llagostera,M.,Gottschalk,M.,&Barbe,J.(2010)。,The cation-uptake regulators AdcR and fur are necessary for full virulence of streptococcus suis.,兽医微生物学,144(1-2),246-249。DOI:10.1016 / J.Vetmic.2009.12.037 [DOI]
    Huuskonen,M.T.,Tuo,Q.Z.,Loppi,S.,Dhungana,H.,Korhonen,P.,Mcinnes,L. E.,。。。Kanninen,K. M.(2017)。,通过调节炎性Milieu,铜BIS(硫代硫代噻吩)复合Cu(II)(ATSM)是对脑缺血的保护性。《神经治疗学:美国实验神经治疗学会杂志》,14(2),519-532。doi:10.1007/s13311-016-0504-9 [内政部]
    Savignac,H. M.,Hyland,N.P.,Dinan,T. G.,&Cryan,J.F。(2011),重复社会交互应激对应激敏感小鼠行为和生理参数的影响。《行为大脑研究》,216(2),576-584。doi:10.1016/j.bbr.2010.08.049 [内政部]
    巴拉多斯,A. M.,Yuan,H.,Van der Stok,J.,Le Quang,B.,Fernandes,H.,Chaterjea,A.,。。。De Boer,J.(2012)。,遗传因素对小鼠磷酸钙陶瓷骨诱导电位的影响。,生物材料,33(23),5696-5705。DOI:10.1016 / J.Biomaterials.2012.04.021 [DOI]
    Roper, J., O'Carroll, A. M., Young, W.,3rd, & Lolait, S. (2011).,The vasopressin Avpr1b receptor: Molecular and pharmacological studies, Stress (Amsterdam, Netherlands), 14(1), 98-115. doi:10.3109/10253890.2010.512376 [doi]
    Makdasi E,Amsili S,Aronin A,Prigozhina TB,Tzdaka K,Gozlan YM,Ben Gigi-Tamir L,Ben Gigi-Tamir L,Sagiv Jy,Shkedy F,Shani N,Tykocinski Ml,Dranitzki Elhalel M.,无毒,高效,靶向六聚体FASL:CTLA4-FASL的小鼠毒理学和药代动力学研究, Mol Cancer Ther. 2020 Feb;19(2):513-524. doi: 10.1158/1535-7163.MCT-19-0558. Epub 2019 Dec 23.
    城市,P.,Valle-Delgado,J. J.,Mauro,N.,Marques,J.,Manfredi,A.,Rottmann,M.,。。。Fernandez-Busquets,X.(2014)。,使用聚(酰胺胺)药物缀合物用于向疟原虫递送抗疟药,中国控释杂志:第177,84-95号控释会官方刊。DOI:10.1016 / J.JCONREL.2013.12.032 [DOI]
    Terwisscha Van Scheltinga,A.G.,Berghuis,P.,Nienhuis,H. H.,Timmer-Bosscha,H.,Pot,L.,Gaykema,S. B.,。。。Schroder,C. P.(2014)。,Visualising dual downregulation of insulin-like growth factor receptor-1 and vascular endothelial growth factor-A by heat shock protein 90 inhibition effect in triple negative breast cancer.,欧洲癌症杂志(牛津,英国:1990),50(14),2508-2516。DOI:10.1016 / J.EJCA.2014.06.008 [DOI]
    Liu, Y., Hughes, T. C., Muir, B. W., Waddington, L. J., Gengenbach, T. R., Easton, C. D., . . . Qiu, J. (2014).,水分散磁性碳纳米管作为T2加权MRI造影剂,生物材料,35(1),378-386。DOI:10.1016 / J.Biomaterials.2013.09.079 [DOI]

    teratology

    克雷格,M.,&Slauch,J. M.(2009),吞噬超氧化物特异性损害了抑制或杀死沙门氏菌的绝经靶标。, PloS One, 4(3), e4975. doi:10.1371/journal.pone.0004975 [doi]
    Montalban-Soler,L.,Alarcon-Martinez,L.,Jimenez-Lopez,M.,Salinas-Navarro,M.,Galindo-Romero,C.,Bezerra de Sa,F.,。。。Villegas-Perez,M. P.(2012)。,在白化小鼠中损伤后视网膜补偿​​变化。, Molecular Vision, 18, 675-693.
    Kawedia, J. D., Janke, L., Funk, A. J., Ramsey, L. B., Liu, C., Jenkins, D., . . . Relling, M. V. (2012).,小鼠模型中存活和骨瘦如柴的特异性差异。,比较医学,62(6),466-471。
    Williams,L.K.,Csaki,L. S.,Cantor,R. M.,Reue,K.,&Lawson,G. W.(2012)。,C57BL / 6小鼠中的溃疡性皮炎表现出与正常伤口愈合一致的氧化应激反应, Comparative Medicine, 62(3), 166-171.

    毒理学

    Kienhuis,A. S.,Slob,W.,Gremmer,E. R.,Vermeulen,J.P.,&Ezendam,J.(2015)。,剂量 - 响应建模方法表明,混合物暴露于皮肤敏化剂异屈酚和肉桂的影响与剂量添加而不是协同作用, Toxicological Sciences : An Official Journal of the Society of Toxicology, 147(1), 68-74. doi:10.1093/toxsci/kfv109 [doi]
    Ezendam,J.,vermeulen,J.P.P.,De Klerk,A.,De Jong,W.H.,沃尔·莱戈伦,H.(2012)。,定量评估皮肤敏化剂在诱导期的效能的方法。,毒理学,299(1),20-24。DOI:10.1016 / J.Tox.2012.05.002 [DOI]
    Kavanagh, H., & Mahon, B. P. (2011).,异基因间充质干细胞通过诱导小鼠调节性T细胞,预防过敏性气道炎症。, Allergy, 66(4), 523-531. doi:10.1111/j.1398-9995.2010.02509.x [doi]
    刘,C.,Janke,L.J.,Kawedia,J. D.,Ramsey,L. B.,Cai,X.,Mattano,L. A.,Jr,。。。撕裂,M。V.(2016)。,天冬酰胺酶增强糖皮质激素诱导的小鼠模型中的骨折。,plos一个,11(3),e0151433。DOI:10.1371 / journal.pone.0151433 [DOI]
    Rosáriof,duarte,如果,pinto rjb,santos c,hoet phm,oliveira h.,急性腹腔内滴注后小鼠银纳米粒子的生物分布和肺代谢效应,环境科学污染res int。2021年1月; 28(2):2301-2314。DOI:10.1007 / S11356-020-10563-Z。EPUB 2020 SEP 3。
    Nygaard, U. C., Vinje, N. E., Samuelsen, M., Andreassen, M., Groeng, E. C., Bolling, A. K., . . . Bodin, J. (2015).,早期生命暴露于双酚A调查的气道过敏,食物过敏和口腔耐受性。, Food and Chemical Toxicology : An International Journal Published for the British Industrial Biological Research Association, 83, 17-25. doi:10.1016/j.fct.2015.05.009 [doi]
    Janecek,E.,Beineke,A.,Schnieder,T.,&Strube,C。(2014)。,Neurotoxocarosis: Marked preference of toxocara canis for the cerebrum and T. cati for the cerebellum in the paratenic model host mouse., Parasites & Vectors, 7, 194-3305-7-194. doi:10.1186/1756-3305-7-194 [doi]
    Aranda,J.,Garrido,M. E.,Fittipaldi,N.,Cortes,P.,Llagostera,M.,Gottschalk,M.,&Barbe,J.(2009)。,Protective capacities of cell surface-associated proteins of streptococcus suis mutants deficient in divalent cation-uptake regulators.,微生物学(阅读,英格兰),155(PT 5),1580-1587。DOI:10.1099 / MIC.0.026278-0 [DOI]
    Purcell,B. P.,Elser,J.A.,Mu,A.,Margulies,K。B.,&Burdick,J. A.(2012)。,SDF-1alpha趋化因子与可降解水凝胶透明质酸释放的协同作用,可将骨髓源性细胞定向心肌。, Biomaterials, 33(31), 7849-7857. doi:10.1016/j.biomaterials.2012.07.005 [doi]
    Veiga,J.P.,Cooper,P. A.,Pors,K.,Patterson,L.H.,Bibby,M. C.,&Shigyder,S。D.(2011),中空纤维测定法用于评价DNA损伤剂。, Journal of Pharmacological and Toxicological Methods, 64(3), 226-232. doi:10.1016/j.vascn.2011.04.006 [doi]